Clinical trials
Safety and Tolerability in Healthy Volunteers clinical trials
Below are recruiting safety and tolerability in healthy volunteers clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06859333RecruitingPhase 1
Safety study of Ingavirin Forte in healthy volunteers
This trial tests how safe and tolerable different doses of Ingavirin Forte are in healthy people. It helps find the right dose for future studies.
MoscowAges 18–45 - NCT05648214RecruitingPhase 1/Phase 2
Testing a new liver medicine in people with fatty liver
This early-phase study tests whether ALN-PNP is safe and well tolerated, first in healthy adults and then in adults with MASLD (fatty liver disease). If you have MASLD, it may help researchers learn whether this medicine is a promising option for treating liver fat buildup.
Glendale, CaliforniaAges 18–75 - NCT06867393RecruitingPhase 1
Safety study of HL-003 in healthy volunteers
This trial tests a new medicine called HL-003 in healthy people to see if it is safe and how the body processes it. You may join if you are generally healthy, between 18 and 50 years old, and meet specific health and lifestyle requirements.
Suzhou, JiangsuAges 18–50 - NCT00004577Recruiting
New Brain Imaging Methods Research Study
This research study tests new ways to take detailed pictures of your brain using MRI (a safe imaging machine). You'll help researchers develop better imaging methods by lying still in the scanner for up to 2 hours.
Bethesda, MarylandAges 18–120 - NCT06786676RecruitingPhase 1
Safety study of AS-S603 in healthy volunteers
This trial tests a new drug called AS-S603 in healthy volunteers to see if it is safe and how the body processes it. It is an early-phase study for people of Korean or Caucasian background.
SeoulAges 19–85 - NCT07407543RecruitingPhase 1
Study of SRN001 in healthy Korean and Caucasian men
This trial tests a new drug called SRN001 in healthy men to see how safe it is and how the body processes it. It may help find the right dose for future studies.
SeoulAges 19–60 - NCT07254481RecruitingPhase 1
Safety study of VB19055 in healthy volunteers
This trial tests a new drug (VB19055) in healthy volunteers to see how safe it is and how the body processes it. Participants will be watched closely and may help find the right dose for future studies.
HangzhouAges 18–50 - NCT07099118RecruitingPhase 1
Safety and tolerability of HEC169584 in healthy people
This early-stage study checks if a new medicine called HEC169584 is safe for people and how it moves through the body. It looks for healthy volunteers to take part.
Beijing, Beijing MunicipalityAges 18–45 - NCT06782958Enrolling by invitationPhase 1
Safety study of FHND1002 granules in healthy adults
This trial tests a new medication called FHND1002 in healthy adults aged 18 to 45. The goal is to check its safety, how well the body tolerates it, and how it is processed. It is one of the first tests in humans.
Lanzhou, GansuAges 18–45 - NCT06620679Recruiting
Brain inflammation and stress in healthy men
This study explores how inflammation in the body affects the brain's response to stress. Healthy men will have brain scans and stress tests to understand this link better.
Leuven, Flemish BrabantAges 18–45 - NCT07758985RecruitingPhase 1
Testing a pill's safety and effect on mosquitoes in healthy adults
This study tests a new pill called lotilaner for safety and how well it works to kill mosquitoes that carry malaria. It is for healthy adults in Mali and may help future malaria prevention efforts.
BamakoAges 18–55 - NCT07016802RecruitingPhase 1
Study of GenSci134 for growth hormone deficiency
This trial tests a new growth hormone treatment called GenSci134 in healthy adults and adults with growth hormone deficiency (AGHD). The goal is to see if it is safe and effective for people who need growth hormone replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT06466525RecruitingPhase 1
Testing LBT-3627 for safety in healthy adults and people with Parkinson's
This study tests an investigational drug called LBT-3627 to see if it is safe and how the body processes it. It includes healthy volunteers and people with Parkinson's disease, and may help determine if the drug could be a future treatment.
Melbourne, VictoriaAges 30–89 - NCT07483827RecruitingPhase 1
Testing CPV-104 safety in healthy people and C3G patients
This trial tests a new drug called CPV-104. First, healthy volunteers will receive a single dose to check safety. Then, people with C3 glomerulopathy (a rare kidney disease) will receive multiple doses to see if it helps and is safe.
ViennaAges 18 years+ - NCT07749768RecruitingPhase 1
Oral drug for ulcerative colitis safety study
This study tests an investigational oral drug for ulcerative colitis. It is an early-stage trial to check safety and how the drug is processed by the body in both healthy volunteers and patients with active ulcerative colitis.
Miami, FloridaAges 18–55 - NCT07371065Enrolling by invitationPhase 1
Testing a new drug's safety in healthy adults
This trial tests a new medicine called LY03021 in healthy volunteers to see how safe it is, how the body processes it, and if food changes its effects. It's for people who are generally healthy and not taking other medications.
ShanghaiAges 18–45 - NCT07760467RecruitingPhase 1
Study of an oral medication for safety in healthy adults
This study tests an investigational oral medication called TUL321 in healthy volunteers to see if it is safe and how the body handles it. It may help understand the drug's effects and is an early step in developing a new treatment.
Changsha, HunanAges 18–45 - NCT07507838RecruitingEarly Phase 1
Safety study of VV913 capsules in healthy male volunteers
This early-phase trial tests VV913 capsules in healthy men to see how safe they are and how the body processes the drug. It may help find the right dose for future studies.
Hefei, AnhuiAges 18–45 - NCT06948799RecruitingPhase 1
Safety study of STSP-0902 in healthy men
This study tests a new drug called STSP-0902 to see if it is safe in healthy men. It may help men with low sperm count or poor sperm movement, but the main goal is to check for side effects.
Beijing, Beijing MunicipalityAges 18–50 - NCT06674694RecruitingPhase 1
Testing brexpiprazole long-acting shot for schizophrenia
This study tests an injectable form of brexpiprazole that stays in the body for a long time. It aims to see if the shot is safe and tolerable for healthy volunteers and people with schizophrenia, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–65 - NCT07449572RecruitingPhase 1
Safety study of HT31-1 for healthy volunteers
This trial tests a new drug called HT31-1 to see if it's safe in healthy people. It looks at how the drug moves in your body and if it causes side effects. This is a first step before testing it in patients with ARDS (a serious lung condition).
Richmond, VirginiaAges 18–65 - NCT06565195RecruitingPhase 1
Study of an investigational drug for Parkinson's disease
This study tests an experimental drug called LY3962681 in two groups: healthy volunteers and people with Parkinson's disease. The goal is to see if the drug is safe and how the body handles it, which may lead to future treatments for Parkinson's.
Englewood, ColoradoAges 30–80 - NCT03721822RecruitingPhase 1
Imaging how smoking affects lung inflammation in adults
This Phase 1 study uses special lung imaging to measure inflammation after different types of smoking or vaping. It looks at differences between people and may help researchers understand how smoking-related lung irritation develops.
Philadelphia, PennsylvaniaAges 18–45 - NCT06714006RecruitingPhase 1
Testing safety of PYC-003 for ADPKD
This study is testing a new investigational medicine called PYC-003 for people with autosomal dominant polycystic kidney disease (ADPKD). It is one of the first studies in humans, so the main goal is to see if the medicine is safe and tolerable. The study is for people with a specific genetic cause (PKD1 mutation) and with certain kidney imaging types.
Southport, Gold CoastAges 18–65
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Common questions
- Are there clinical trials for safety and tolerability in healthy volunteers?
- Yes. Clin2 currently lists 74 recruiting safety and tolerability in healthy volunteers studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and tolerability in healthy volunteers trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and tolerability in healthy volunteers trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.