Clinical trials
Sarcoma clinical trials
Below are recruiting sarcoma clinical trials, each written for real people, not researchers. We’re tracking 402 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07650656RecruitingPhase 2
Fluorescence-Guided Surgery to Improve Sarcoma Tumor Removal
This trial tests a special dye and imaging technique to help surgeons see and remove sarcoma tumors more completely. The goal is to reduce the chance that cancer cells are accidentally left behind during surgery.
Duarte, CaliforniaAges Any age - NCT07642375Recruiting
Digital Tools to Manage Sarcoma Treatment Side Effects
This study tests whether a digital app or online tool can help you better manage symptoms and side effects from your sarcoma treatment. Researchers want to see if tracking your symptoms online improves how you feel during cancer care.
AthensAges 18 years+ - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07602777RecruitingPhase 1/Phase 2
Testing Risvutatug Rezetecan for Advanced Bone and Soft Tissue Sarcomas
This study tests a new cancer drug called risvutatug rezetecan for people with advanced sarcomas (bone or soft tissue cancers) that have stopped responding to prior treatments. The drug works by delivering a cancer-killing agent directly to tumor cells.
West Valley City, UtahAges Any age - NCT07467772RecruitingPhase 2
Elacestrant for estrogen receptor-positive uterine sarcoma
This trial tests whether elacestrant, a drug that blocks estrogen, can help people with certain types of uterine sarcoma that have strong estrogen receptors. It may slow or stop cancer growth in tumors that rely on estrogen.
Boston, MassachusettsAges 18 years+ - NCT07402577Recruiting
Pain and opioid use in young sarcoma survivors
This study looks at pain and opioid use in adolescents and young adults who have had sarcoma. It uses a smartphone app to track symptoms over 3 months to better understand cancer-related pain.
Buffalo, New YorkAges 12–70 - NCT03886311RecruitingPhase 2
Talimogene, nivolumab, and trabectedin for advanced sarcoma
This Phase 2 study tests a combination treatment for locally advanced or metastatic sarcoma that cannot be fully removed by surgery. It aims to shrink tumors and control disease by combining an injected cancer-killing medicine with two cancer-fighting drugs.
Santa Monica, CaliforniaAges 18 years+ - NCT07291297RecruitingPhase 2
Metformin plus standard therapy for soft tissue sarcoma
This trial tests adding metformin, a common diabetes drug, to the usual first cancer treatment for advanced soft tissue sarcoma. It may help the standard therapy work better.
Charlotte, North CarolinaAges 18 years+ - NCT06889532Recruiting
Wound care after sarcoma surgery: vacuum or standard dressing?
This study compares two wound care methods after surgery to remove a large sarcoma (a type of cancer) from the leg or groin. It tests whether a special vacuum dressing helps the wound heal better than standard care.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04758325Recruiting
Sarcoma biology and outcomes registry
This trial is a health registry that collects information about people with soft-tissue or bone sarcoma. It helps researchers understand how the disease behaves and what outcomes different treatments lead to.
Heidelberg, Baden-WurttembergAges 12 years+ - NCT07188532Recruiting
Personalized high-dose radiation for Ewing sarcoma
This trial tests a personalized radiation therapy that adjusts the dose based on your tumor. It aims to improve treatment for Ewing sarcoma while limiting side effects.
Phoenix, ArizonaAges 2 years+ - NCT07134192Recruiting
Using a dye to guide sarcoma surgery
This trial tests a special dye that helps surgeons see the edges of sarcoma tumors during surgery. It may help them remove all the cancer while saving healthy tissue.
Aarhus NAges 18 years+ - NCT07032285RecruitingPhase 2
Cirtuvivint for advanced soft-tissue sarcomas
This trial tests a new drug called Cirtuvivint for people with certain advanced soft-tissue sarcomas that have grown recently. It aims to see if the drug can stop or slow tumor growth.
Madrid, MadridAges 16–70 - NCT06943612Recruiting
Studying colon surgery in retroperitoneal sarcoma patients
This study looks at people with rare abdominal sarcomas who also had part of their colon removed during surgery. It aims to understand how these combined surgeries affect outcomes, helping doctors better care for future patients.
Mannheim, Baden-WurttembergAges 18 years+ - NCT06942442RecruitingPhase 2
Tebentafusp for advanced clear cell sarcoma
This trial tests if a drug called tebentafusp can help people with advanced clear cell sarcoma that cannot be removed by surgery or has spread. It is for people with a specific immune marker (HLA-A*02:01) whose disease has gotten worse.
Los Angeles, CaliforniaAges 18 years+ - NCT06941194Recruiting
Preventing wound problems after sarcoma surgery with a special bandage
This trial tests a special negative pressure bandage used after surgery to prevent wound complications in people with high-grade soft tissue sarcoma of the limbs who have had radiation therapy before their operation.
Padova, Italy/PadovaAges 18–99 - NCT06114004RecruitingPhase 2
Selinexor plus gemcitabine for advanced soft-tissue sarcoma
This trial tests a combination of two drugs, selinexor and gemcitabine, for people with a type of soft-tissue sarcoma (leiomyosarcoma or malignant peripheral nerve sheath tumor) that has spread or cannot be surgically removed and has gotten worse despite at least one prior treatment. The goal is to see if this combination can help shrink or slow the cancer.
Santa Cruz de Tenerife, Canary IslandsAges 18–80 - NCT06797999RecruitingPhase 1/Phase 2
Study of ADCE-D01 for soft tissue sarcoma
This trial tests a new drug called ADCE-D01 for people with soft tissue sarcoma that has spread or cannot be removed by surgery. The goal is to see if it is safe and effective.
Aurora, ColoradoAges 18 years+ - NCT06796543Recruiting
Radiation for young patients with sarcoma that has spread
This trial tests whether targeted radiation can help children and young adults with sarcoma that has spread to a few spots in the body. It's for those who are newly diagnosed (Stratum A) or whose sarcoma has come back or worsened (Stratum B).
Washington D.C., District of ColumbiaAges Up to 39 years - NCT06298916RecruitingPhase 1/Phase 2
Study of 64Cu-LNTH-1363S in Sarcoma or GI Cancer
This trial tests a new imaging agent, 64Cu-LNTH-1363S, to see if it can find certain sarcomas and gastrointestinal cancers. The goal is to help doctors better see where your cancer is and plan the best treatment. You may be eligible if you have a sarcoma or a GI cancer and are willing to have a tumor tissue sample taken.
Duarte, CaliforniaAges 15 years+ - NCT03978039Recruiting
Sarcoma patient registry for people treated in France
This trial builds a national database of people diagnosed with sarcoma in French cancer centers. It may help researchers better understand sarcoma types and care patterns, which can improve future treatment decisions.
BordeauxAges Any age - NCT06409013Recruiting
Dye-guided surgery for sarcoma removal
This study tests whether using a special dye during surgery helps doctors see and remove sarcoma tumors more completely. It may help improve the chances that no cancer is left behind.
Rochester, MinnesotaAges 18 years+ - NCT06211257Recruiting
Digital info vs standard leaflets for advanced sarcoma
This trial is testing a digital tool (like videos or online info) to help people with advanced sarcoma understand their treatment better. It compares the digital tool to standard printed leaflets to see which improves understanding and wellbeing.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT06156410RecruitingPhase 1
Cabozantinib and ifosfamide for relapsed sarcomas
This study tests a combination of two drugs, cabozantinib and ifosfamide, for sarcomas that have come back or not responded to treatment. The goal is to see if this combination can help shrink or control the cancer.
San Francisco, CaliforniaAges 5–40
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Common questions
- Are there clinical trials for sarcoma?
- Yes. Clin2 currently lists 402 recruiting sarcoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sarcoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sarcoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.