Clinical trials
Schizoaffective Disorder clinical trials
Below are recruiting schizoaffective disorder clinical trials, each written for real people, not researchers. We’re tracking 43 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04580134RecruitingPhase 4
Clozapine study for people with a specific schizophrenia or bipolar type
This trial tests whether clozapine works better for people whose illness fits a specific “biotype-1” pattern. It may help reduce ongoing symptoms, but it also requires close safety monitoring.
Hartford, ConnecticutAges 18–60 - NCT06071858Recruiting
Enhanced coordinated care for early psychosis
This trial studies an enhanced version of coordinated specialty care (CSC) for people experiencing their first episode of psychosis. It aims to improve outcomes by providing more intensive support and coordination among different healthcare providers.
Belmont, MassachusettsAges Any age - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT01392885Recruiting
Brain health and exercise program for schizophrenia
This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.
Vancouver, British ColumbiaAges 19–45 - NCT07818668Recruiting
Brain stimulation for self-other boundaries in schizophrenia
This study tests a gentle brain stimulation method called transcranial alternating current stimulation (tACS) to see if it can help people with schizophrenia better tell the difference between themselves and others, which may reduce symptoms like hallucinations and delusions.
Hefei, AnhuiAges 18–50 - NCT07696000Recruiting
Nutrition therapy for inflammation in schizophrenia
This trial tests whether a structured medical nutrition plan can reduce inflammation in people with schizophrenia who are on stable antipsychotic medication. If you are hospitalized and able to eat normally, this study may help you understand how diet affects your health.
MedanAges 18–60 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT07058389Recruiting
Exercise in green spaces for schizophrenia symptoms
This study tests whether combining physical activity with being in green outdoor spaces can reduce the tough symptoms of schizophrenia, like feeling flat or unmotivated. It's designed for people whose negative symptoms are not going away.
Saint-Etienne, FranceAges 18–55 - NCT06745479Recruiting
Understanding decision-making in schizophrenia with brain scans
This study uses brain scans and real-life surveys to understand how people with or without schizophrenia make decisions. It may help researchers learn how the brain works differently in schizophrenia.
Piscataway, New JerseyAges 18–50 - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT06562608RecruitingPhase 4
Reducing Anticholinergic Medications in Schizophrenia
This trial is testing whether it is safe to slowly reduce or stop anticholinergic medications (benztropine or trihexyphenidyl) in people with schizophrenia. It aims to see if stopping these drugs can help with thinking and memory without causing worsening movement problems.
Pittsburgh, PennsylvaniaAges 40–70 - NCT06286202Recruiting
Cognitive skills program for schizophrenia recovery
This trial tests a community-based program called INSPIRE that uses mental exercises and social coaching to help people with schizophrenia or schizoaffective disorder improve their thinking skills and daily functioning. It is conducted in English and requires at least 10 years of English-language education.
SingaporeAges 21–60 - NCT05805397Recruiting
Motivation skills training for schizophrenia or schizoaffective disorder
This study tests whether “Motivation Skills Training” can help people with schizophrenia or schizoaffective disorder. It’s for people who are stable on treatment and can participate in English-speaking sessions.
New York, New YorkAges 18–65 - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT04226898RecruitingPhase 2
Synbiotic supplement to lessen schizophrenia symptoms
This Phase 2 trial tests whether a “synbiotic” supplement (a mix of probiotics and prebiotics) can reduce symptoms of schizophrenia or schizoaffective disorder. It may help by targeting gut-related immune and inflammation pathways that could affect brain symptoms.
Batlimore, MarylandAges 18–65 - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT01409109Recruiting
Study database for brain signal markers in psychosis
This study builds a database of brain-signal measurements to help find “biomarkers” that may point to schizophrenia or related mental illnesses. Depending on whether you have a mental health diagnosis or you’re healthy, the study will collect information and brain data to compare groups.
Dallas, TexasAges 18–60 - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70
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Common questions
- Are there clinical trials for schizoaffective disorder?
- Yes. Clin2 currently lists 43 recruiting schizoaffective disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizoaffective disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizoaffective disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.