Clozapine to prevent violence in schizophrenia
Treatments studied
Part of Mental health clinical trials.
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of schizophrenia or schizoaffective disorder confirmed by a structured interview
- You had a minor or serious act of violence in the last 6 months
- You can give informed consent and your clinician says you are medically stable for study treatment
- Your current treatment situation allows you to be eligible for either clozapine or usual care (with specific medication timing rules)
- You do not have major unstable medical or neurological conditions, especially serious bone-marrow problems
- You are not allergic or unable to take clozapine before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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