Clinical trials
Schizophrenia and Other Psychotic Disorders clinical trials
Below are recruiting schizophrenia and other psychotic disorders clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06978803Recruiting
Speech and brain study for early psychosis
This study looks at how people with early psychosis (within the first 5 years of treatment) talk during conversations. Researchers hope to learn more about speech patterns and brain activity related to psychosis.
Montreal, QuebecAges 18–60 - NCT07397975Recruiting
Using speech to predict relapse in psychosis
This study uses speech recordings from a smartphone app to see if changes in the way you talk can predict when someone might have a relapse of psychosis. It is for people who are currently stable or for healthy volunteers to compare.
KlecanyAges 18–65 - NCT06978881Enrolling by invitation
Brain activity study for stable schizophrenia
This study uses a brain scan called magnetoencephalography (MEG) to understand brain activity in people with schizophrenia. It may help researchers learn more about the condition and could lead to better treatments.
Montreal, QuebecAges 18–50 - NCT06745479Recruiting
Understanding decision-making in schizophrenia with brain scans
This study uses brain scans and real-life surveys to understand how people with or without schizophrenia make decisions. It may help researchers learn how the brain works differently in schizophrenia.
Piscataway, New JerseyAges 18–50 - NCT06882785RecruitingPhase 3
Testing KarXT for Japanese adults with schizophrenia
This trial tests a new medication called KarXT for people with schizophrenia who are currently having a psychotic episode. It is for Japanese adults who have had schizophrenia before and are not in their first episode.
Kōnan, Aichi-kenAges 18–65 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT05945602Recruiting
Using brain signals to guide cognitive rehab in psychosis
This study looks at brain-wave or related “brain signal” measurements to better guide cognitive rehabilitation (thinking and memory skills). It may help people with long-term psychotic disorders, and it also may include healthy comparison volunteers to understand the signals.
San Diego, CaliforniaAges 18–75 - NCT06336382Recruiting
Tau protein study in late-onset psychosis
This study looks at brain proteins called tau in people who develop psychosis later in life (after age 60). Researchers want to understand how these proteins relate to symptoms, which may help find better treatments.
Manhasset, New YorkAges 65–85 - NCT01980147Recruiting
Skills for Wellness program for youth coping with mental health risks
This trial tests a structured skills program to help children and teens (ages 9–21) cope with early mental health warning signs such as anxiety, mood swings, or unusual thoughts. It may help participants build practical coping tools and well-being.
Halifax, Nova ScotiaAges 9–21 - NCT07408934Enrolling by invitation
Group therapy for feeling safer with psychosis
This trial tests a group therapy program called the Feeling Safe Programme for people with psychosis. It aims to help you learn new ways to cope with your symptoms and feel safer. It meets once a week for 75 minutes.
Ottawa, OntarioAges 18 years+ - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT07119268Recruiting
Sleep quality study for college students
This study tests whether a sleep program can help college students who have trouble sleeping. You may qualify if you have poor sleep and some unusual experiences, but have never been diagnosed with a psychotic disorder.
Indianapolis, IndianaAges 18–65 - NCT05962216Recruiting
Real-world check of Rexulti for schizophrenia and depression
This study looks at how well brexpiprazole (Rexulti) works in everyday treatment, and how people feel and function over time. You may be eligible if you’re newly started on Rexulti and have a qualifying mental health diagnosis.
Hong KongAges 18–65 - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT07748091Recruiting
Brain wave and inflammation markers in shock therapy for depression
This study looks at brain wave patterns and markers of inflammation in people with depression that hasn't improved with other treatments and who are receiving electroconvulsive therapy (ECT, also known as shock therapy). The goal is to understand how these markers might relate to how well ECT works.
Istanbul, BakırköyAges 18–60 - NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07441928Recruiting
Smoking and brain connections in schizophrenia
This study looks at how smoking affects brain networks in people with schizophrenia. It uses brain scans to see differences between smokers and non-smokers.
Hong KongAges 18 years+ - NCT02670447Recruiting
Checking new support for a first psychosis, no prior medication
This trial looks at people having a first psychotic episode who have not yet taken anti-psychotic medicine. It aims to see whether an early support approach can help, before other treatments become necessary.
BronAges 18–35
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Common questions
- Are there clinical trials for schizophrenia and other psychotic disorders?
- Yes. Clin2 currently lists 90 recruiting schizophrenia and other psychotic disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia and other psychotic disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia and other psychotic disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.