Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 306 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07288567RecruitingPhase 3
KarXT for teens with schizophrenia
This trial tests if a new medicine, KarXT, can safely and effectively treat schizophrenia in adolescents. It may help teenagers who have active symptoms like hallucinations or disorganized thinking.
Anaheim, CaliforniaAges 13–17 - NCT06882538Recruiting
Mindfulness program for schizophrenia patients
This study tests if a one-on-one mindfulness-based psychoeducation program can help reduce internalized stigma and promote healthy lifestyle behaviors in people with schizophrenia. It aims to provide a supportive approach to improve well-being.
Kastamonu, CentralAges 18 years+ - NCT07273175Enrolling by invitation
Can brain stimulation improve thinking in schizophrenia?
This study tests if a safe, non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve cognitive functions like memory and attention in people with schizophrenia. If you are between 18 and 65, have a schizophrenia diagnosis, and are mentally stable, you may be eligible.
Lodz, Łódź VoivodeshipAges 18–65 - NCT07265180Recruiting
Oxytocin and group therapy for schizophrenia
This trial tests whether adding oxytocin (a hormone that helps with social bonding) to group therapy can improve symptoms and social functioning in people with schizophrenia. It compares two different doses of oxytocin to see which works better.
Berlin, State of BerlinAges 18–75 - NCT07234708Recruiting
Feeling Safe Study for people with persecutory delusions
This study tests a psychological treatment for people with schizophrenia who feel unsafe because they believe others are trying to harm them. The goal is to help reduce these fears and improve daily life.
BarcelonaAges 18 years+ - NCT07227818RecruitingPhase 3
Testing NBI-1117568 to prevent schizophrenia relapse
This trial tests a new medicine, NBI-1117568, to see if it can help prevent a relapse of schizophrenia symptoms. It is for adults who have been stable on other antipsychotics and want to avoid returning to the hospital for a psychiatric stay.
Garden Grove, CaliforniaAges 18–65 - NCT07225712RecruitingPhase 3
Long-term study of an experimental drug for stable schizophrenia
This trial tests a new medication called SEP-363856 over a long period for people with schizophrenia who are currently stable. It looks at how well the drug works and its safety over time.
FukuokaAges 18 years+ - NCT06936397Recruiting
Cognitive therapy for schizophrenia: Brain changes and emotions
This trial tests a cognitive training program for people with schizophrenia to see if it improves thinking and emotional control, and how it affects brain activity measured by EEG.
IstanbulAges 18–55 - NCT02455193Recruiting
Exercise study for people with schizophrenia
This study looks at how exercise affects brain function in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can improve brain-related outcomes alongside standard treatment.
Aurora, ColoradoAges 21–70 - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT07191483RecruitingPhase 2
Study of KYN-5356 for cognitive problems in schizophrenia
This trial tests an investigational drug, KYN-5356, to see if it can improve thinking and memory problems in adults with schizophrenia. You may join if your schizophrenia is stable and you take only one antipsychotic medication.
Little Rock, ArkansasAges 18–55 - NCT07184619RecruitingPhase 3
Evenamide for hard-to-treat schizophrenia (add-on study)
This trial tests a new medication, evenamide, added to your current antipsychotic treatment. It looks to see if it can help people whose schizophrenia has not responded well to standard therapies.
Los Angeles, CaliforniaAges 18 years+ - NCT07177261Recruiting
Brain synchrony study for schizophrenia
This study looks at how brain activity syncs between people with schizophrenia and others. It aims to understand social interaction differences—potentially leading to better treatments.
Los Angeles, CaliforniaAges 18–65 - NCT07176468Recruiting
Personalized brain stimulation for schizophrenia in real-world settings
This study tests a personalized form of brain stimulation called iTBS for people with schizophrenia. It aims to see if it works in everyday clinical settings.
Hefei, AnhuiAges 18–60 - NCT07173192Enrolling by invitation
Empowerment program for schizophrenia caregivers
This trial tests a program designed to support relatives who care for someone with schizophrenia. It aims to help caregivers feel more confident and capable.
Istanbul, CevizlibağAges 18–65 - NCT07162467Enrolling by invitation
Exploring metabolism and thinking in schizophrenia
This trial looks at how a natural chemical pathway in the body might relate to thinking problems in people with schizophrenia. It compares healthy volunteers to people with schizophrenia to find biological clues.
TianjinAges 18–55 - NCT07145918RecruitingPhase 2
Study of an oral schizophrenia drug for adults
This trial tests an experimental oral drug (emraclidine) to see if it helps symptoms of schizophrenia and how it moves through the body. It looks at two groups of participants: those with stable symptoms and those having an acute flare-up.
Little Rock, ArkansasAges 18–65 - NCT07139171Recruiting
Plasma exosome role in thinking problems in first-episode schizophrenia
This study looks at tiny particles called exosomes in your blood and how small molecules inside them called microRNAs may affect thinking and memory in people with a first episode of schizophrenia. If you join, your blood will be used to help find new ways to understand and treat cognitive symptoms.
TianjinAges 18–65 - NCT07144592Recruiting
Solutions-focused therapy for schizophrenia adjustment
This study tests a talking therapy approach that focuses on solutions to help people with schizophrenia adjust better to daily life and stick with their treatment. It is offered through a Community Mental Health Center.
MuşAges 18–65 - NCT07121166Recruiting
Family therapy by video for schizophrenia
This trial tests a family therapy program delivered through video calls to help people with schizophrenia and their families. You would join group sessions with other families to learn ways to support each other and reduce stress.
Chai WanAges 18–64 - NCT07122895RecruitingPhase 2
NMDA enhancer for negative symptoms in schizophrenia
This study tests whether a medication that boosts brain NMDA receptors can improve negative symptoms in schizophrenia, and looks at differences between men and women. It is for people with stable schizophrenia who still have mostly flat mood or low motivation.
TaichungAges 20–65 - NCT07114874RecruitingPhase 3
A long-term study of a new drug for schizophrenia
This study tests a new medicine called NBI-1117568 for adults with schizophrenia over a longer period of time. Participants will stop their current antipsychotics and take this new drug to see how well it works and how safe it is.
Bryant, ArkansasAges 18–65 - NCT07105098RecruitingPhase 3
Study of a new drug for schizophrenia in hospitalized adults
This study tests an experimental drug (NBI-1117568) for people with schizophrenia who are currently in the hospital due to worsening symptoms. Participants stop their current antipsychotic and take the study drug to see if it can help control symptoms.
Little Rock, ArkansasAges 18–65 - NCT06386588Recruiting
Sound during sleep for brain health in schizophrenia
This study tests if playing sounds during sleep can improve brain function in people with schizophrenia. You will be asked to do a finger tapping task while we measure your brain activity with MRI.
Charlestown, MassachusettsAges 18–45
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 306 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.