Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06236048Recruiting
Brain energy and glutamate in schizophrenia
This study uses brain scans (MRI and PET) to look at energy use and a brain chemical called glutamate in people with schizophrenia. It compares healthy volunteers to those with well-controlled schizophrenia and those with hard-to-treat schizophrenia to understand the biology better.
LondonAges 18–65 - NCT07696000Recruiting
Nutrition therapy for inflammation in schizophrenia
This trial tests whether a structured medical nutrition plan can reduce inflammation in people with schizophrenia who are on stable antipsychotic medication. If you are hospitalized and able to eat normally, this study may help you understand how diet affects your health.
MedanAges 18–60 - NCT06562608RecruitingPhase 4
Reducing Anticholinergic Medications in Schizophrenia
This trial is testing whether it is safe to slowly reduce or stop anticholinergic medications (benztropine or trihexyphenidyl) in people with schizophrenia. It aims to see if stopping these drugs can help with thinking and memory without causing worsening movement problems.
Pittsburgh, PennsylvaniaAges 40–70 - NCT06340789RecruitingPhase 2
Sodium Benzoate Added to Antipsychotics for Resistant Schizophrenia
This study tests whether adding a supplement called sodium benzoate to your current antipsychotic medication can improve symptoms in schizophrenia that hasn't responded well to standard treatments. Researchers will measure brain chemistry changes and symptom improvement over time.
Chiayi CityAges 20–55 - NCT06341517Recruiting
Brain circuit therapy for schizophrenia
This trial tests a noninvasive brain stimulation treatment (TMS) to improve symptoms of schizophrenia. It aims to target brain circuits that may be out of balance.
GenevaAges 18–65 - NCT06345963Recruiting
Brain stimulation to improve connectivity in schizophrenia
This study tests if brain stimulation can improve how different brain regions communicate in people with schizophrenia. It may help improve thinking and daily function.
Houston, TexasAges 18–60 - NCT06351514RecruitingPhase 3
Accelerated brain stimulation for negative symptoms of schizophrenia
This trial tests a faster form of brain stimulation called accelerated intermittent theta burst stimulation to help with persistent negative symptoms of schizophrenia. Negative symptoms include things like lack of motivation, reduced emotion, or social withdrawal.
SingaporeAges 21–65 - NCT06361160Recruiting
Brain stimulation for treatment-resistant voices in schizophrenia
This trial tests a brain stimulation treatment (rTMS) to help reduce the frequency and intensity of voices people with schizophrenia hear. It is for individuals who continue to hear voices frequently despite trying multiple medications.
ParisAges 18 years+ - NCT06361407Recruiting
Understanding predictions in schizophrenia
This study looks at how people with schizophrenia process sensory information and make predictions. It aims to understand disruptions in these processes to improve future treatments.
MarseilleAges 18–60 - NCT06386588Recruiting
Sound during sleep for brain health in schizophrenia
This study tests if playing sounds during sleep can improve brain function in people with schizophrenia. You will be asked to do a finger tapping task while we measure your brain activity with MRI.
Charlestown, MassachusettsAges 18–45 - NCT06431009Recruiting
Danish schizophrenia study for recent first episodes
This study follows people who have recently been diagnosed with a first episode of schizophrenia, schizoaffective disorder, or are at ultra-high risk for psychosis. Researchers want to learn more about how these conditions develop over time to improve early care and treatment.
AarhusAges 15 years+ - NCT06470516Recruiting
Brain stimulation for cognitive issues in schizophrenia
This study tests a type of brain stimulation called high-definition transcranial alternating current stimulation (hi-tACS) to see if it can improve thinking and memory in people with schizophrenia. If you are a right-handed adult with stable schizophrenia, you may be able to join.
Hanzhou, ZhejiangAges 18 years+ - NCT06482554RecruitingPhase 3
Lumateperone for Apathy in Psychotic Disorders
This trial tests a medication called lumateperone to see if it can improve apathy (lack of motivation) in people who have psychotic symptoms from schizophrenia or related disorders. It may help if you are already on a stable treatment but still struggle with apathy.
Shreveport, LouisianaAges 18–65 - NCT06482918Recruiting
Cognitive training for schizophrenia: testing brain flexibility
This trial tests a cognitive remediation program to see if it can improve thinking skills in people with schizophrenia. It also looks at how the brain changes with this training.
Santiago, RMAges 18–59 - NCT06484387Recruiting
Studying social interaction in schizophrenia
This trial looks at how people with schizophrenia and healthy volunteers synchronize during conversations. It aims to understand social difficulties in schizophrenia.
MontpellierAges 18–60 - NCT06494124Recruiting
Brain stimulation for schizophrenia symptoms
This study compares two types of mild brain stimulation—tACS and tDCS—to see if they can help reduce symptoms of schizophrenia. It is for people who have had moderate to severe symptoms for at least two years and are on stable medications.
Bhubaneswar, OdishaAges 18–60 - NCT06502964RecruitingPhase 2
ALTO-101 study for schizophrenia cognitive symptoms
This study tests an experimental medication called ALTO-101 for people with schizophrenia who also have cognitive impairment (memory or thinking problems). It aims to see if the drug can improve these symptoms while you continue your current antipsychotic treatment.
Garden Grove, CaliforniaAges 21–55 - NCT06573320Recruiting
Exercise for schizophrenia patients on clozapine
This trial tests whether a regular exercise program can help improve symptoms, thinking, and quality of life for people with schizophrenia who take a specific medication called clozapine.
IstanbulAges 18–65 - NCT06574360RecruitingPhase 2
Study of a dual-target drug for hard-to-treat schizophrenia
This trial tests an experimental combination treatment that targets two different brain receptors (sigma-1 and NMDA) to see if it can improve symptoms in people with schizophrenia that hasn't responded well to standard antipsychotics.
TaichungAges 18–65 - NCT06599372Recruiting
TMS for resistant voices in schizophrenia
This trial tests if a non-invasive brain stimulation method called transcranial magnetic stimulation (TMS) can reduce stubborn auditory hallucinations (hearing voices) in people with schizophrenia who haven't improved enough with medication.
Neuilly-sur-MarneAges 18 years+ - NCT06613334Recruiting
Voice recordings to predict schizophrenia relapse
This study tests whether voice recordings can help predict when someone with schizophrenia might have a relapse. It is for people who are stable now and take certain medications.
Paris, ParisAges 18–60 - NCT06617104Recruiting
Nervous system and energy study for schizophrenia
This study looks at how the nervous system and energy pathways in your body work in people with schizophrenia. It aims to find differences that could help improve future treatments.
TaipeiAges 18–65 - NCT06641297Recruiting
Brain Wiring Study in Schizophrenia
This study uses MRI scans to look at brain changes in people with schizophrenia. It aims to understand how the brain's wiring (called white matter) changes over time.
Catonsville, MarylandAges 15–45 - NCT06642675Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests whether a non-invasive brain stimulation technique called nTMS (repetitive transcranial magnetic stimulation) can help reduce negative symptoms of schizophrenia, like lack of motivation or social withdrawal. It's a possible treatment option for people with stable schizophrenia who still struggle with these symptoms.
Changsha, HunanAges Up to 60 years
Hear when a new Schizophrenia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 317 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.