Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 306 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07074704Enrolling by invitation
Brain stimulation to improve symptoms and thinking in schizophrenia
This study tests whether a gentle electrical current applied to the scalp (transcranial alternating current stimulation, or tACS) can help reduce negative symptoms and improve thinking in people with long-term schizophrenia. It is for patients who have been hospitalized for over six months and are on stable medication.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07055204Recruiting
Music-based cognitive training for schizophrenia
This study tests a special music-based training program that uses rhythm, voice, and body movements to help with thinking and memory skills in people with schizophrenia. It might improve how your brain processes information.
BayonneAges 18–60 - NCT07060066Recruiting
TMS for depression in schizophrenia
This study tests whether a type of brain stimulation called TMS (transcranial magnetic stimulation) can help with depression in people who have schizophrenia. You would receive TMS sessions targeting areas of the brain linked to mood, and the goal is to see if this improves depression symptoms.
Houston, TexasAges 18–60 - NCT07045142RecruitingPhase 3
Metformin for blood sugar issues from statins in schizophrenia
This trial tests whether metformin can help prevent or manage blood sugar problems that may arise when people with schizophrenia take statins (cholesterol-lowering drugs). If you have schizophrenia, are on a stable medication routine, and have high cholesterol but not diabetes, this study might be an option.
Zhumadian, HenanAges 18–65 - NCT07010614Recruiting
Brain stimulation for memory in schizophrenia
This trial uses brain stimulation to target memory areas in people with schizophrenia or related conditions. It aims to see if this can help improve symptoms.
Stanford, CaliforniaAges 18–65 - NCT06888726Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests if a gentle electric current applied to your head can help with negative symptoms (like lack of motivation or emotion). You must have schizophrenia, take a common antipsychotic, and have some ongoing negative symptoms.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06963034RecruitingPhase 3
Study of a new medicine for adults with schizophrenia
This trial tests an investigational medicine called NBI-1117568 in adults with schizophrenia who are currently having a relapse or worsening of symptoms and need to stay in the hospital. The goal is to see if the medicine is safe and effective.
Bryant, ArkansasAges 18–65 - NCT06961968RecruitingPhase 3
Schizophrenia medication withdrawal study
This study tests whether patients with schizophrenia can safely stop or reduce their current medication without worsening symptoms. It is designed for people who need ongoing psychiatric care.
Rogers, ArkansasAges 18–65 - NCT06961916Recruiting
Brain stimulation to improve connections in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can improve brain connections in people with schizophrenia. It involves two types of MRI scans and several TMS sessions to see if it can help with thinking and symptoms.
Houston, TexasAges 18–60 - NCT06957808Recruiting
Diroximel fumarate brain health study for schizophrenia
This trial tests if a drug called diroximel fumarate can help increase a natural antioxidant (glutathione) in the brain for people with schizophrenia. It aims to see if lowering inflammation and boosting brain protection might improve symptoms.
London, Greater LondonAges 18–65 - NCT06911931Recruiting
Visual perception study in schizophrenia and bipolar disorder
This study looks at how people with schizophrenia or bipolar disorder see the world. By comparing their visual perception to people without these conditions, researchers hope to learn more about how the brain processes what we see.
Rochester, New YorkAges 18–65 - NCT06882785RecruitingPhase 3
Testing KarXT for Japanese adults with schizophrenia
This trial tests a new medication called KarXT for people with schizophrenia who are currently having a psychotic episode. It is for Japanese adults who have had schizophrenia before and are not in their first episode.
Kōnan, Aichi-kenAges 18–65 - NCT06821945RecruitingPhase 2
Olanzapine dosing study for schizophrenia
This trial tests a slower, lower-dose schedule of the drug olanzapine for people with schizophrenia. It aims to see if a gentler start is safer and works as well, especially for those who may need less medication due to other health conditions.
DaeguAges 19 years+ - NCT06745479Recruiting
Understanding decision-making in schizophrenia with brain scans
This study uses brain scans and real-life surveys to understand how people with or without schizophrenia make decisions. It may help researchers learn how the brain works differently in schizophrenia.
Piscataway, New JerseyAges 18–50 - NCT06740747Recruiting
Brain stimulation for schizophrenia symptoms
This study tests a new type of brain stimulation (called intermittent theta-burst stimulation) to see if it helps with symptoms like lack of motivation or trouble thinking clearly in people with schizophrenia. You will also have an MRI scan to see how the brain changes.
Hanover, Lower SaxonyAges 18–65 - NCT06740383Recruiting
Study of early psychosis and treatments
This study looks at people who have had psychosis for less than 4 years to understand how their symptoms change over time and how they respond to treatment. By using brain scans and other tests, researchers hope to find better ways to personalize care for early psychosis.
Hartford, ConnecticutAges 18–40 - NCT06674694RecruitingPhase 1
Testing brexpiprazole long-acting shot for schizophrenia
This study tests an injectable form of brexpiprazole that stays in the body for a long time. It aims to see if the shot is safe and tolerable for healthy volunteers and people with schizophrenia, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–65 - NCT05731414Recruiting
Testing behavior programs to improve outcomes in schizophrenia
This study looks at how a behavioral program (including remediation and behavior-based techniques) may improve outcomes for adults with schizophrenia-spectrum conditions. You may be eligible if you meet basic age/language needs and haven’t done certain therapies recently.
Scarborough Village, OntarioAges 18–65 - NCT06642675Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests whether a non-invasive brain stimulation technique called nTMS (repetitive transcranial magnetic stimulation) can help reduce negative symptoms of schizophrenia, like lack of motivation or social withdrawal. It's a possible treatment option for people with stable schizophrenia who still struggle with these symptoms.
Changsha, HunanAges Up to 60 years - NCT06641297Recruiting
Brain Wiring Study in Schizophrenia
This study uses MRI scans to look at brain changes in people with schizophrenia. It aims to understand how the brain's wiring (called white matter) changes over time.
Catonsville, MarylandAges 15–45 - NCT06613334Recruiting
Voice recordings to predict schizophrenia relapse
This study tests whether voice recordings can help predict when someone with schizophrenia might have a relapse. It is for people who are stable now and take certain medications.
Paris, ParisAges 18–60 - NCT06574360RecruitingPhase 2
Study of a dual-target drug for hard-to-treat schizophrenia
This trial tests an experimental combination treatment that targets two different brain receptors (sigma-1 and NMDA) to see if it can improve symptoms in people with schizophrenia that hasn't responded well to standard antipsychotics.
TaichungAges 18–65 - NCT04807530Recruiting
MRI brain study for people with schizophrenia symptoms
This study uses brain scans to look at how a specific brain area works in schizophrenia. If you qualify, it may help researchers better understand the brain changes linked to symptoms.
San Francisco, CaliforniaAges 18–64
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Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 306 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.