Clinical trials · Florida
Seizures clinical trials in Florida
We’re tracking 18 recruiting seizures studies with a site in Florida — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Gulf Breeze, FloridaAges 12 years+ - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Gulf Breeze, FloridaAges 18–75 - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Boca Raton, FloridaAges 12 years+ - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Maitland, FloridaAges 18–75 - NCT07287163Enrolling by invitationPhase 3
Long-term study of vormatrigine for epilepsy
This trial is for adults with epilepsy who have already taken vormatrigine in a previous study or through a special access program. It aims to collect ongoing safety and effectiveness information.
Miami, FloridaAges 18–85 - NCT05219617RecruitingPhase 3
Carisbamate for frequent drop seizures in Lennox-Gastaut
This Phase 3 study tests whether carisbamate can reduce drop seizures in people with Lennox-Gastaut syndrome (LGS). It also checks whether the treatment is safe when added to existing seizure medicines.
Wellington, FloridaAges 4–55 - NCT05667142RecruitingPhase 3
Testing an add-on drug for hard-to-control generalized convulsive seizures
This Phase 3 trial tests XEN1101 added to your current seizure medicines for people with primary generalized tonic-clonic seizures. It’s for seizures that have not fully stopped even after trying at least two appropriate medicines.
Jacksonville, FloridaAges 12 years+ - NCT05716100RecruitingPhase 3
Study drug for focal epilepsy that isn’t controlled on current meds
This trial tests XEN1101 compared with a placebo (inactive pill) in people with focal-onset seizures that haven’t been fully controlled despite trying at least two anti-seizure medicines. If you qualify, you may help researchers see whether the study drug reduces seizure frequency and improves control.
Jacksonville, FloridaAges 18 years+ - NCT06798896RecruitingPhase 2
SPN-817 for hard-to-control focal seizures
This study tests an investigational drug called SPN-817 to see if it can reduce focal seizures (seizures that start in one area of the brain) in adults whose seizures are not well controlled by current medications.
Port Charlotte, FloridaAges 18–70 - NCT06908356RecruitingPhase 2
Testing PRAX-628 for focal or tonic-clonic seizures
This study tests an experimental pill called PRAX-628 for adults whose seizures are not fully controlled by current medications. It aims to see if the drug is safe and effective at reducing seizures.
Miami Lakes, FloridaAges 18–75 - NCT07141329RecruitingPhase 2
Long-term study of SPN-817 for focal seizures
This study gives SPN-817 to people who completed a prior study of the same drug, to see if it stays safe and works well over a longer time. You may qualify if you already finished that study and have stable seizure medicine.
Port Charlotte, FloridaAges 18 years+ - NCT07233239RecruitingPhase 1
CBD liquid for focal epilepsy seizures
This trial tests a new cannabidiol (CBD) liquid medicine for people with focal epilepsy (seizures that start in one part of the brain). It looks at whether the medication can help reduce seizures when added to your current seizure medications.
Tampa, FloridaAges 12–75 - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT06027749Recruiting
Long-term home EEG monitoring for people with seizures
This study is testing a wearable EEG device that you can use at home for up to 30 days. It records brain activity to help doctors better understand your seizures. The goal is to see if this longer monitoring can capture more seizure events than standard short-term EEG tests.
Tampa, FloridaAges 18–70 - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Jacksonville, FloridaAges 12 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Miami, FloridaAges 18–66 - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT07445074Recruiting
AI phone app to help teens and young adults with epilepsy take their medicine
This study tests a mobile app that uses artificial intelligence to help people with epilepsy remember to take their anti-seizure medication. It is for teens and young adults (ages 14-24) living in Florida who are from underserved communities.
Orlando, FloridaAges 14–24
Where these studies are running in Florida
Institutions with a site for the recruiting seizures studies listed above.
- University of South Florida · 5 studies
- Mayo Clinic · 3 studies
- Medsol Clinical Research Center · 3 studies
- Serenity Research Center · 3 studies
- Encore Medical Research of Weston · 2 studies
- Ep016 · 2 studies
- Ep0162 · 2 studies
- Ep0162 50509 · 2 studies
What taking part in a seizures study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Seizures trials in other states
Common questions
- Are there seizures clinical trials in Florida?
- Yes. We're currently tracking 18 recruiting seizures studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a seizures study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New seizures studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.