Clinical trials · California
Seizures clinical trials in California
We’re tracking 17 recruiting seizures studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05121324RecruitingPhase 3
Tested higher-dose seizure medicine for children during EMS care
This trial studies the best dose of a seizure medicine for children who are actively seizing while emergency medical teams are treating them. It may help EMS crews give safer, more effective treatment during transport.
Los Angeles, CaliforniaAges 6 months–13 years - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Palo Alto, CaliforniaAges 18 years+ - NCT06952764Enrolling by invitation
ECLIPSE: Tracking epilepsy cycles to predict seizures
This trial tests if tracking your brain activity with an implanted device can help predict when seizures might happen. It is for adults who have seizures despite medication and already have the RNS System implanted.
San Francisco, CaliforniaAges 18 years+ - NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Downey, CaliforniaAges 12 years+ - NCT07563881RecruitingPhase 3
Testing RAP-219 for Focal Seizure Control in Adults
This study tests whether a new medication called RAP-219 can help adults with focal seizures (seizures that start in one area of the brain) control their seizures better. You would take this medication alongside your current seizure drugs for about 12 weeks.
Palmdale, CaliforniaAges 18–75 - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Downey, CaliforniaAges 12 years+ - NCT05851391RecruitingPhase 2
Test drug treatment to stop hard-to-control seizures after cardiac arrest
This Phase 2 trial tests a medication strategy to stop “refractory status epilepticus,” a severe seizure condition that can happen after a cardiac arrest. It may help by reducing ongoing seizure activity after return of circulation in the ICU.
San Francisco, CaliforniaAges 18 years+ - NCT05219617RecruitingPhase 3
Carisbamate for frequent drop seizures in Lennox-Gastaut
This Phase 3 study tests whether carisbamate can reduce drop seizures in people with Lennox-Gastaut syndrome (LGS). It also checks whether the treatment is safe when added to existing seizure medicines.
Palo Alto, CaliforniaAges 4–55 - NCT05667142RecruitingPhase 3
Testing an add-on drug for hard-to-control generalized convulsive seizures
This Phase 3 trial tests XEN1101 added to your current seizure medicines for people with primary generalized tonic-clonic seizures. It’s for seizures that have not fully stopped even after trying at least two appropriate medicines.
Los Angeles, CaliforniaAges 12 years+ - NCT05716100RecruitingPhase 3
Study drug for focal epilepsy that isn’t controlled on current meds
This trial tests XEN1101 compared with a placebo (inactive pill) in people with focal-onset seizures that haven’t been fully controlled despite trying at least two anti-seizure medicines. If you qualify, you may help researchers see whether the study drug reduces seizure frequency and improves control.
Orange, CaliforniaAges 18 years+ - NCT07233239RecruitingPhase 1
CBD liquid for focal epilepsy seizures
This trial tests a new cannabidiol (CBD) liquid medicine for people with focal epilepsy (seizures that start in one part of the brain). It looks at whether the medication can help reduce seizures when added to your current seizure medications.
La Jolla, CaliforniaAges 12–75 - NCT06401707RecruitingPhase 2
Seizure prevention after cardiac arrest
This study tests a seizure-prevention medicine called perampanel for people whose hearts stopped beating (cardiac arrest) and are now in the ICU. The goal is to see if it helps prevent seizures that can happen after such an event.
San Francisco, CaliforniaAges 18 years+ - NCT06265103Recruiting
Epilepsy learning healthcare system registry
This is a registry study that collects information from people being treated for epilepsy at participating healthcare centers. The goal is to improve care by learning from real-world patient data.
Los Angeles, CaliforniaAges Any age - NCT05718817Enrolling by invitationPhase 3
Long-term study of XEN1101 for people with epilepsy
This study gives XEN1101 in an open-label way (everyone knows they’re getting the drug) to people who finished earlier epilepsy studies. It aims to see how the treatment continues to work and whether it’s safe over the long term.
Los Angeles, CaliforniaAges 12 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Palo Alto, CaliforniaAges 18–66 - NCT07226908Enrolling by invitation
Brain electrode study for epilepsy and memory
This study places electrodes in the brain to learn how seizures spread and how memory works. It may help people with temporal lobe epilepsy understand their condition better and improve future treatments.
Stanford, CaliforniaAges 18–65
Seizures trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting seizures studies listed above.
- University of California, Irvine Medical Center / UC Irvine Health · 3 studies
- Brain Science Research Institute · 2 studies
- Children's Hospital Los Angeles · 2 studies
- Ep0162 50118 · 2 studies
- Ep0162 50716 · 2 studies
- Long Beach City Hospital · 2 studies
- Site 50722 · 2 studies
- Stanford University · 2 studies
What taking part in a seizures study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Seizures trials in other states
Common questions
- Are there seizures clinical trials in California?
- Yes. We're currently tracking 17 recruiting seizures studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a seizures study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a seizures trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New seizures studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.