Clinical trials
Sepsis, Severe clinical trials
Below are recruiting sepsis, severe clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06481410Recruiting
Methylene blue for severe septic shock
This trial is testing whether a medication called methylene blue can help people with severe septic shock who are already on strong blood pressure support (norepinephrine). The goal is to see if it improves survival and reduces the need for other treatments.
Hangzhou, ZhejiangAges Any age - NCT05788861Recruiting
Study for children with severe strep skin or bloodstream infection
This trial is for people under 18 who have a confirmed invasive Group A strep infection, meaning strep bacteria found in places that are normally sterile (like the blood or deep tissues). It tests whether a specific study approach can help improve outcomes for children with these serious infections.
CréteilAges 1 day–17 years - NCT07063095RecruitingPhase 3
Testing two antibiotics combined for serious bacterial infections
This study tests whether combining two antibiotics (ceftazidime and fosfomycin) works better than ceftazidime alone for hospitalized adults with serious bacterial infections. If you have a severe infection thought to be caused by Gram-negative bacteria, this trial may offer a new treatment option.
Geneva, Canton of GenevaAges 18 years+ - NCT05181696Recruiting
Study of chest X-ray severity scores in ICU COVID-19 pneumonia
This study reviews past chest X-rays from people who were hospitalized in the ICU for COVID-19 pneumonia caused by SARS-CoV-2. It aims to see how well a chest X-ray severity scoring system reflects how sick the lungs were.
OsijekAges 18–90 - NCT07130799Recruiting
Monitoring immune response in severe abdominal infections with fungal risk
This trial monitors a marker of immune function (monocyte HLA-DR) in patients with severe abdominal infections that may lead to fungal infections. It aims to see if this marker can help guide treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT05565222RecruitingPhase 3
Testing two antibiotics as alternatives for ICU severe ESBL infections
This study compares two antibiotics—piperacillin-tazobactam or temocillin—to treat severe ICU infections caused by certain hard-to-treat gut bacteria (ESBL). It may help patients avoid the use of carbapenem antibiotics like meropenem when the bacteria are susceptible.
ParisAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+
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Common questions
- Are there clinical trials for sepsis, severe?
- Yes. Clin2 currently lists 32 recruiting sepsis, severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis, severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis, severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.