Clinical trials
Sepsis and Septic Shock clinical trials
Below are recruiting sepsis and septic shock clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05491941Recruiting
Testing ways to improve care for sepsis patients
This trial looks at how to best put proven sepsis care steps into practice in the emergency department. It may help you or other patients receive faster, more consistent treatment for sepsis.
Providence, Rhode IslandAges 18 years+ - NCT02936232Recruiting
Registry for severe sepsis and septic shock
This registry collects medical information from adults who have suspected or proven serious infection causing body organ problems. It helps researchers better understand what happens in severe sepsis and septic shock and may guide future care.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT06226441Recruiting
Aminoglycoside antibiotics for sepsis with low kidney function
This study tests how well aminoglycoside antibiotics work in people with sepsis who also have low kidney function. It may help find the best way to treat serious infections in patients with kidney problems.
Larissa, ThessalyAges 18 years+ - NCT04448951Recruiting
Study of immune response in early sepsis or septic shock
This trial looks at how the immune system behaves in the first day after septic shock begins. It may help researchers find better ways to support the body’s immune balance during sepsis, but you must be enrolled very quickly.
Pilsen, Česká RepublikaAges 18 years+ - NCT07774962Recruiting
Comparing fingertip refill time and blood oxygen use in septic shock
This study looks at two ways to check blood flow and oxygen use in people with septic shock, a severe infection-related condition. It aims to see if a simple bedside test (fingertip refill) and a blood measure (oxygen extraction ratio) agree, which could help guide treatment.
IstanbulAges 18 years+ - NCT04513288Recruiting
Immunonutrition with L-citrulline for ICU sepsis patients
This trial tests whether adding L-citrulline to tube feeding (enteral nutrition) can improve outcomes for people in the ICU with sepsis or septic shock. It may help support the body’s immune response while you’re critically ill.
Rennes, Brittany RegionAges 18 years+ - NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT07716956Recruiting
Magnesium therapy for severe septic shock
This trial tests whether raising magnesium levels in the blood to a normal upper range can help reduce the need for strong blood pressure medications in people with severe septic shock. It might help stabilize blood pressure and improve recovery.
Alexandria, Alexandria GovernorateAges 18 years+ - NCT07706413Recruiting
Plasma exchange for children with severe sepsis
This trial tests whether removing harmful substances from the blood (plasma exchange) can help children with severe infections that cause organ failure or very low blood pressure. If your child is in the hospital with severe sepsis or septic shock and is between 1 month and 18 years old, this treatment might be an option.
Shibīn al Kawm, Menoufia GovernorateAges 1 month–18 years - NCT07616817Enrolling by invitation
Expert Panel Study on Ultrasound Assessment of Septic Shock
This study gathers expert opinions from critical care doctors and specialists around the world who use bedside ultrasound (a portable imaging tool) to diagnose and categorize septic shock (a life-threatening infection condition). The goal is to develop standardized approaches to identifying different types of septic shock using ultrasound.
Albany, New YorkAges Any age - NCT07597122Recruiting
Blood markers study in septic shock patients
This research study measures special blood markers (microRNAs) in patients with septic shock or critical illness to understand how the body responds to severe infection. Results may help doctors better diagnose and treat sepsis in the future.
BernAges 18 years+ - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT07582926Recruiting
Cortisol Levels and Outcomes in Critically Ill Infection Patients
This study examines how the body's stress hormone (cortisol) relates to survival in patients with severe blood infections in the ICU. Understanding this relationship may help doctors better predict and manage outcomes in critically ill patients.
AnkaraAges 18 years+ - NCT06670963RecruitingPhase 4
Epoetin alfa and iron for anemia in sepsis
This trial tests whether a combination of epoetin alfa (a medicine that boosts red blood cell production) and iron derisomaltose (an iron supplement) can safely treat anemia in people with sepsis or septic shock. It may help improve your energy and recovery.
KatowiceAges 18 years+ - NCT07539883Recruiting
Septic Shock Treatment With Special Kidney-Filter Devices
This study looks back at how a special kidney filter called oXiris helped patients in the ICU who had septic shock (a life-threatening blood infection) and kidney failure. Researchers want to understand if this filter improved survival and recovery compared to standard treatment.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07516236Recruiting
Using blood oxygen levels to guide fluid treatment in septic shock
This trial is studying whether a measure of oxygen in your blood (called SvO2) can help doctors decide if giving you more fluids will help improve your blood pressure during septic shock. The goal is to make fluid treatment more precise and avoid giving too much fluid.
MenoufAges 18 years+ - NCT06786364Recruiting
Measuring blood flow waves in sepsis patients
This study uses a special light sensor to measure blood flow waves in patients with septic shock. The goal is to see if these waves can help doctors understand how severe the shock is.
Mexico City, CuauhtemocAges 18 years+ - NCT07451886RecruitingPhase 2
Fludrocortisone for septic shock
This study tests whether adding a steroid called fludrocortisone to standard care helps people with septic shock (a dangerous drop in blood pressure from infection) get better faster. If you are in the ICU, on a breathing machine, and need strong medication for your blood pressure, you may be eligible.
Hong KongAges 18 years+ - NCT07388628Recruiting
Observing ARTICE® treatment in the ICU
This study is collecting real-world data on ARTICE® treatment for adults in the ICU. It helps doctors understand how this treatment works in daily practice.
MagdeburgAges 18 years+ - NCT06545838Recruiting
Testing renin levels to predict septic shock severity
This trial checks if a blood test measuring renin (a kidney hormone) can help predict how severe septic shock will be and how well patients recover. It looks for early clues in ICU patients with sepsis.
MoscowAges 18 years+ - NCT05726825Recruiting
Add-on plasma exchange for new septic shock
This study tests whether adding plasma exchange (a blood-cleaning treatment) to usual care can improve outcomes for people with new septic shock. If you qualify, you may receive this treatment soon after septic shock is diagnosed to help your body recover.
InnsbruckAges 18–80 - NCT06898723RecruitingPhase 4
Shenfu injection to prevent heart problems in sepsis
This trial tests whether Shenfu injection can help prevent heart muscle damage in people with septic shock. If you have septic shock, you may be able to join this study to see if this treatment helps protect your heart.
Wuhu, AnhuiAges 18 years+ - NCT06072430RecruitingPhase 3
Testing a new fluid for septic shock with low blood pressure
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
Chandler, ArizonaAges 18 years+ - NCT07203833Recruiting
Vasorin test for shock diagnosis and outlook
This study looks at a protein called vasorin in the blood to see if it can help diagnose and predict outcomes in people with severe shock in the ICU. It compares patients with septic shock (caused by infection) to those with shock from other causes.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for sepsis and septic shock?
- Yes. Clin2 currently lists 87 recruiting sepsis and septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis and septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis and septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.