Clinical trials
Serious Illness clinical trials
Below are recruiting serious illness clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05491538Recruiting
Work skills training for Veterans living with serious mental illness
This study tests whether a social-skills training program designed for work goals is doable and helpful for Veterans with serious mental illness. It focuses on improving work-related coping and interactions while you receive supported services through the VA.
Minneapolis, MinnesotaAges 18 years+ - NCT05674617Recruiting
PTSD treatment for Veterans with serious mental illness
This trial tests a PTSD treatment approach for Veterans who also have a serious mental illness, aiming to improve day-to-day functioning. It includes Veterans who receive outpatient mental health care through the VA and have confirmed PTSD in the last month.
Baltimore, MarylandAges 18 years+ - NCT05703711Recruiting
MHealth plus nurse care for mental health in West Africa
This trial tests whether combining phone-based support (mHealth) with regular nurse-delivered care can improve outcomes for people with serious mental illness. You might benefit if you’re currently in an inpatient prayer camp and living with psychosis, mania, or depression.
AccraAges 18 years+ - NCT05962879Recruiting
Program for teens with early psychosis-like experiences
This trial tests a new mental health program for teenagers who are having at least one psychosis-like experience and may be at risk for serious mental illness. It may help by offering structured support for both teens and their parents.
Boston, MassachusettsAges 14–19 - NCT05537376Recruiting
Peer-led suicide prevention support for veterans with serious mental illness
This study tests a suicide-prevention program delivered by trained peer specialists (other people with similar lived experience) to help veterans who are currently having suicidal thoughts. It aims to add ongoing support and improve safety and recovery for veterans with serious mental health conditions.
San Diego, CaliforniaAges 18 years+ - NCT06641726Recruiting
Global database linking genetics and health records for mental illness
This trial is building a research database that combines genetic information and long-term health data to improve personalized treatment for serious mental illness. You may be eligible if you have been diagnosed or treated for depression, bipolar disorder, schizophrenia, or dementia.
Oxford, OxfordAges 18–110 - NCT07312760Recruiting
Talking therapy for existential distress in advanced cancer
This trial compares a short-term psychodynamic therapy (ORPHYS) with usual care for people with advanced cancer who are struggling with existential distress, such as loss of hope, fear of death, or loneliness. It aims to see if this therapy can help improve emotional well-being.
DüsseldorfAges 18 years+ - NCT07518446Recruiting
Health Screening for Adults Starting Psychiatric Care
This study checks the physical health of adults beginning treatment for serious mental illnesses like schizophrenia or depression at two Danish clinics. It aims to catch health problems early that people with these conditions often experience.
CopenhagenAges 18 years+ - NCT07264062Enrolling by invitation
MetSense pilot study for serious mental illness
This pilot study is testing a program for people with serious mental illness like schizophrenia or bipolar disorder. It aims to see if adding a special monitoring tool helps manage treatment better.
Pleasanton, CaliforniaAges 18 years+ - NCT07134751Recruiting
Febrile Infants Swedish Study
This study looks at babies 60 days or younger who have a fever of 100.4°F or higher. It aims to better understand and manage fevers in young infants.
GothenburgAges Up to 2 months
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Common questions
- Are there clinical trials for serious illness?
- Yes. Clin2 currently lists 34 recruiting serious illness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a serious illness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a serious illness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.