Clinical trials
Soft Tissue Injuries clinical trials
Below are recruiting soft tissue injuries clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04757337RecruitingPhase 3
Oral chemotherapy comparison for older advanced soft-tissue cancer
This trial compares two chemotherapy medicines—oral cyclophosphamide versus doxorubicin—in people age 65 and older with advanced soft-tissue sarcoma that can’t be cured with surgery or radiation. It aims to see which treatment works better and is more tolerable for this age group.
ToulouseAges 65 years+ - NCT05679284Recruiting
Study for retained needle fragments in people who inject drugs
This observational study looks at whether small pieces of drug-injection needles remain in injection sites. You may help by answering a questionnaire and getting X-ray images, which could improve how care and safety are handled for people who inject drugs.
TampereAges 18 years+ - NCT07293702Recruiting
IASTM therapy for shoulder pain from impingement
This study tests a hands-on therapy called IASTM (instrument-assisted soft tissue mobilization) to see if it can reduce pain, improve movement, and help your shoulder feel more stable. It is for people with subacromial impingement syndrome, a common cause of shoulder pain.
IstanbulAges 40–60 - NCT07611864Recruiting
Patient Experience with Oxygen Therapy for Radiation Injury
This study asks patients who have received hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) to help doctors understand how well it works for healing soft tissue damage caused by radiation therapy. Your feedback helps improve care for future patients.
StockholmAges 18 years+ - NCT07444619RecruitingPhase 1
Combination drugs for returning soft tissue sarcoma in young people
This trial tests if combining four drugs (pazopanib, trabectedin, ipilimumab, and nivolumab) can help treat soft tissue sarcomas that have come back. It is for children and young adults up to age 30.
Houston, TexasAges 1–30 - NCT06506838RecruitingPhase 4
Anlotinib, chemo, and radiation before sarcoma surgery
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06603714Enrolling by invitation
Soft tissue massage at different muscle lengths study
This trial tests how soft tissue mobilization affects muscles when stretched compared to relaxed. It may help improve flexibility or recovery in healthy people.
Izola, PrimorskaAges 18–25 - NCT06062927Recruiting
Genes and scans predict response to immunotherapy and targeted therapy for advanced sarcoma
This trial is testing whether a combination of two drugs—a targeted therapy (surufatinib) and an immunotherapy (envafolimab)—can help people with advanced soft tissue sarcoma that has spread or cannot be removed by surgery. Researchers will also use a person's genetic information and scans to see if they can predict who will benefit the most.
Beijing, Beijing MunicipalityAges 18–75 - NCT06637007RecruitingPhase 2
Chidamide plus AK112 for advanced sarcoma after first treatment
This trial tests two new drugs (chidamide and AK112) together for people with advanced bone or soft tissue sarcoma that has not responded to standard first-line treatment. The goal is to see if this combination can shrink tumors or slow their growth.
Taiyuan, ShanxiAges 18–75 - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT05448807RecruitingPhase 3
Phentolamine to reverse numbing from dental local anesthesia in kids
This trial studies whether phentolamine can quickly undo (reverse) the numbness from local anesthesia used during dental procedures in children. It may help kids feel normally sooner and safely use their mouth (like speaking and drinking) after treatment.
Cairo, El ManialAges 5–7 - NCT06848582Recruiting
NK cell therapy for high-risk pediatric soft tissue sarcoma
This trial tests whether giving immune cells called NK cells from donated umbilical cord blood can help children and teens with high-risk or returning soft tissue sarcoma. The goal is to see if it is safe and effective when other treatments have been tried.
Guangzhou, GuangdongAges Up to 18 years - NCT05243966Recruiting
Registry for soft tissue repair using a special matrix
This study is a registry that collects information from people who had soft tissue repair using a specific matrix and/or morcell material. It may help researchers understand how this approach performs in real-world care and patient outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT07576192Recruiting
Massage treatments for heel pain in pregnant women
This study compares two hands-on massage techniques to relieve plantar fasciitis (heel pain) in pregnant women during the second trimester. The goal is to find the most effective, safe way to reduce pain without medication.
Lahore, Punjab ProvinceAges 18–40 - NCT06981637RecruitingPhase 2
PLD vs. observation for advanced soft tissue sarcoma
This trial tests whether a type of chemotherapy called pegylated liposomal doxorubicin (PLD) can help keep advanced soft tissue sarcoma from growing after successful first treatment with standard anthracycline-based chemo. You may be eligible if you've completed 4-8 cycles of that initial chemo and your disease is controlled (shrank or stable).
Kaohsiung CityAges 18 years+ - NCT07090356Recruiting
Soft tissue therapy versus stretching for athletes with piriformis syndrome
This study compares two techniques—instrument-assisted soft tissue mobilization and PNF stretching—to see which works better for reducing pain and improving movement in athletes with piriformis syndrome. It may help if you are an athlete with ongoing buttock or hip pain that makes sitting uncomfortable.
Lahore, Punjab ProvinceAges 18–35 - NCT07260630Enrolling by invitation
Hamstring tightness relief study
This trial tests different massage-type techniques to see which helps tight hamstrings best. If you are between 18 and 30 and have stiff hamstrings, this may help find a quick, drug-free solution.
Ankara, AnkaraAges 18–30 - NCT03896464Recruiting
Quadriceps tendon vs hamstring tendon for ACL surgery in teens
This trial compares using a quadriceps tendon graft versus a hamstring graft during ACL reconstruction in children and teens whose growth plates are still open. It aims to see which graft works better after ACL injury while accounting for ongoing bone growth.
Hamilton, OntarioAges 10–18 - NCT07047846Recruiting
Bowen technique vs. soft tissue therapy for frozen shoulder pain
This study compares two massage-like treatments (Bowen technique and dynamic soft tissue mobilization) to see which better reduces pain, improves movement, and helps daily function in people with frozen shoulder. It only includes diabetic patients with specific stages of frozen shoulder.
Lahore, Punjab ProvinceAges 50–80 - NCT06598644Recruiting
Comparing two gentle neck pain treatments
This study tests two hands-on treatments for long-lasting neck pain: a gentle gliding movement called Sustained Natural Apophyseal Glide (SNAG) and a soft-tissue release technique called Instrument Assisted Soft Tissue Mobilization (IASTM). If you have had neck pain for more than 3 months, this trial may help find which method works better for you.
Rawalpindi, Punjab ProvinceAges 20–45 - NCT07605650Recruiting
Fascia Release Technique for Forward Head Posture
This study tests whether adding a specialized soft-tissue technique (IASTM) to standard physical therapy helps improve forward head posture better than therapy alone. Forward head posture is when your head juts forward, which can cause neck pain and stiffness.
Giza, Giza GovernorateAges 18–30 - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT04589741RecruitingPhase 2
Toripalimab plus CAV/IE for advanced soft-tissue bone cancers
This Phase 2 study tests toripalimab (an immune therapy) combined with CAV/IE chemotherapy for certain advanced or non-surgically removable sarcomas. It may help shrink tumors and slow disease when standard treatments have failed or don’t exist.
GuangzhouAges 14–70
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Common questions
- Are there clinical trials for soft tissue injuries?
- Yes. Clin2 currently lists 30 recruiting soft tissue injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.