Clinical trials
Soft Tissue clinical trials
Below are recruiting soft tissue clinical trials, each written for real people, not researchers. We’re tracking 294 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05944913Recruiting
Testing a special wound dressing after sarcoma tumor removal
This trial compares two types of wound dressings after surgery for soft-tissue sarcoma (STS) that has had radiation therapy. It aims to see whether one dressing helps your wound heal better after tumor removal.
Nantes, Pays de LoireAges 18 years+ - NCT06700070RecruitingEarly Phase 1
Testing a microdose drug in solid tumors before surgery
This study tests a tiny amount of an experimental drug (PBA-0111) injected directly into tumors that will be surgically removed later. The goal is to see how the drug affects the tumor tissue, which may help guide future treatments for solid tumors like head and neck cancer, certain sarcomas, or triple-negative breast cancer.
Shreveport, LouisianaAges 18 years+ - NCT06674538Enrolling by invitationPhase 1
Antibody trial for advanced solid tumors
This trial tests an antibody treatment for people with stage IV cancer that has not responded to previous treatment. It aims to find a new option for patients with several types of advanced solid tumors.
Hershey, PennsylvaniaAges 18 years+ - NCT06674811Recruiting
Childhood cancer surgery recovery study
This study looks at how children and young adults recover after surgery for solid tumors. It also includes their caregivers to understand how resilience affects recovery.
Rochester, MinnesotaAges 3–25 - NCT06664775RecruitingPhase 3
Comparing two bleeding-control patches during open surgery
This study tests a special patch called TachoSil against a standard surgical pad (Surgicel) to see which works better for controlling minor oozing during open abdominal, chest, or pelvic surgeries. It may be an option if you are having certain types of surgery and have a small area of mild bleeding that needs help to stop.
Torrance, CaliforniaAges 1 month+ - NCT06645808RecruitingEarly Phase 1
PET imaging study for various solid tumors
This study uses a special PET scan to see if a new imaging agent can help find and monitor certain solid tumors. It is for people with colon, rectal, sarcoma, breast, lung, head and neck, esophageal, stomach, pancreas, bladder cancers, or glioblastoma who have had standard treatment before surgery.
Groningen, Provincie GroningenAges 18 years+ - NCT06643468Enrolling by invitation
ALB-PRF with bone grafts for immediate dental implants
This trial tests whether using a special protein-rich blood product (ALB-PRF) with two different types of putty-like bone grafts helps improve the success of dental implants placed right after a tooth is removed in the front upper jaw. It may help people who need a tooth replaced in the 'smile zone' and have good oral health.
Al MansurahAges 20–60 - NCT06599957Recruiting
Light-based drug delivery for sarcoma treatment
This trial tests a new light-based drug delivery system to treat sarcomas. It looks at how well this platform works during surgery or biopsy for patients with soft tissue or bone sarcomas.
Bologna, Emilia-RomagnaAges 2–85 - NCT06246656Recruiting
Maxillary expansion with a custom 3D-printed appliance
This trial tests a computer-designed device to widen the upper jaw. It may help people with a narrow upper jaw or a crossbite (when upper teeth sit inside lower teeth).
Vienna, State of ViennaAges 12–26 - NCT06408441Recruiting
EHE registry for rare adult cancers
This study collects information from European hospitals on people with epithelioid hemangioendothelioma (EHE), a rare tumor that grows in blood vessels. Joining this registry helps doctors learn more about the disease and improve care for others.
Graz, GrazAges 18 years+ - NCT06409013Recruiting
Dye-guided surgery for sarcoma removal
This study tests whether using a special dye during surgery helps doctors see and remove sarcoma tumors more completely. It may help improve the chances that no cancer is left behind.
Rochester, MinnesotaAges 18 years+ - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Sarasota, FloridaAges Any age - NCT06343831Recruiting
Measuring fat transfer results for breast reconstruction
This trial uses MRI scans to measure how well a patient's own fat stays after breast or chest wall reconstruction. The goal is to improve our understanding of fat transfer procedures.
Chicago, IllinoisAges 18 years+ - NCT06327477RecruitingPhase 1/Phase 2
A new type of radiation for newly diagnosed retroperitoneal sarcoma
This trial tests a new way of giving radiation called proton spatially fractionated radiotherapy (P-SFRT) combined with standard radiation for people with a type of sarcoma in the back of the belly. The goal is to see if this combination can treat the tumor more effectively.
Chicago, IllinoisAges 18 years+ - NCT06333314RecruitingPhase 2
Dostarlimab for advanced dMMR/MSI cancers (not colorectal or endometrial)
This trial tests a drug called dostarlimab for people with certain advanced cancers that have a specific genetic feature (dMMR/MSI-H). The goal is to see if it helps shrink or control the cancer in people who haven't had other treatments yet.
AngersAges 18 years+ - NCT03751566Recruiting
Acupuncture to ease short-term side effects of head and neck radiation
This trial studies whether adding acupuncture to standard radiation care can reduce short-term side effects from radiation for head and neck tumors. You might qualify if you are having treatment with the goal of cure or after-surgery prevention and can reliably complete symptom/side-effect tracking.
BrnoAges 18 years+ - NCT06211257Recruiting
Digital info vs standard leaflets for advanced sarcoma
This trial is testing a digital tool (like videos or online info) to help people with advanced sarcoma understand their treatment better. It compares the digital tool to standard printed leaflets to see which improves understanding and wellbeing.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT05296564RecruitingPhase 1/Phase 2
TCR cell therapy for NY-ESO-1 positive metastatic cancers
This study tests a customized immune-cell treatment made from your own T cells to attack cancers that have NY-ESO-1. It may help shrink tumors in people with metastatic or hard-to-treat cancer when other treatments have not worked.
JerusalemAges 18–70 - NCT06171750RecruitingPhase 1
Study of ANK-101 for advanced solid tumors
This trial tests a new drug, ANK-101, injected directly into tumors to help fight advanced solid tumors that have spread or can't be treated with standard therapies. It may be an option if you have a tumor that can be reached for injection.
Bethesda, MarylandAges 18 years+ - NCT06129903Recruiting
Early psychiatric help for people with sarcoma
This study tests if getting a psychiatric consultation soon after a sarcoma diagnosis can improve mental health and quality of life. If you have a new sarcoma and need surgery at MSK, you may be able to join.
Basking Ridge, New JerseyAges 18 years+ - NCT05880667RecruitingPhase 1
Adaptive focused radiation for belly and pelvic cancer spread
This Phase 1 study tests an “adaptive” form of focused radiation (SBRT) for cancers that have spread in the abdomen or pelvis. It aims to treat metastatic tumor spots safely while adjusting the plan as needed during treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06073067Recruiting
GRID therapy for extremity soft tissue sarcoma
This trial tests a special type of radiation called GRID therapy for soft tissue sarcomas in the arm or leg. It may be an option for people who have not had radiation to that area before and whose tumor was not completely removed by surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT05950594RecruitingPhase 2
MRI and blood tests study in soft tissue sarcoma
This Phase 2 trial looks at how two test approaches (an MRI-based scan and blood tests) work in people with a larger, grade 2 or 3 soft tissue sarcoma. It may help researchers learn better ways to measure the disease and guide care.
Toronto, OntarioAges 18–100 - NCT05926700RecruitingPhase 2
Testing cadonilimab plus anlotinib for advanced soft tissue sarcoma
This Phase 2 study tests two medicines (cadonilimab and anlotinib) in people with advanced soft tissue sarcoma whose cancer grew after standard first treatment. It aims to see whether the combination can shrink tumors and improve safety.
HangzhouAges 18 years+
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Common questions
- Are there clinical trials for soft tissue?
- Yes. Clin2 currently lists 294 recruiting soft tissue studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a soft tissue trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a soft tissue trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.