Clinical trials
Spinal Surgery clinical trials
Below are recruiting spinal surgery clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07135817Recruiting
Pre-surgery radiation for spinal tumors
This trial tests whether giving focused radiation before surgery can improve treatment for spinal tumors that have spread from other cancers. It may help people who need surgery for a spinal tumor and have a life expectancy of more than 6 months.
GöttingenAges 18 years+ - NCT03492372Enrolling by invitation
Study of molecular changes in removed spinal tissue
This study looks at what’s happening at the molecular level in spinal tissue that is normally removed during surgery. It may help researchers better understand spinal conditions and improve future treatments, using tissue provided as part of routine care.
Rochester, MinnesotaAges 1–80 - NCT05269212Recruiting
Help people with ongoing back pain return to work
This study looks at how to help people with long-lasting spinal pain (PSPS-Type II) get back to work. It may help by testing a plan for managing persistent pain so work becomes more doable.
GhentAges 18–60 - NCT05010148RecruitingPhase 3
IV lidocaine after spinal fusion to reduce delirium and pain
This trial tests whether giving lidocaine through a vein after elective spinal fusion surgery can help prevent confusion (delirium) and reduce pain. It may help people recover more comfortably and think more clearly after surgery.
San Francisco, CaliforniaAges 60 years+ - NCT06591442Enrolling by invitation
Spinal Fusion Recovery in Older Adults
This study is looking at how older adults recover after spinal fusion surgery, a type of back surgery that connects bones in the spine. The goal is to find factors that help people heal faster and feel better afterward.
Wuhan, HubeiAges 60 years+ - NCT06120426Recruiting
Surgery types and radiation for spinal tumors that have spread
This study compares two types of spinal surgery combined with radiation for people whose cancer has spread to the spine in a limited way (no more than 5 spots). It aims to find which approach better controls pain, tumor growth, and spinal stability.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07636135Recruiting
Early rehabilitation timing after neck spine surgery
This study tests whether starting physical therapy sooner after neck spine surgery for degenerative myelopathy (a condition where the spinal cord is compressed) helps patients recover strength, balance, and walking ability faster. You'll do 8 weeks of in-person rehabilitation in Edmonton, Alberta.
Edmonton, AlbertaAges 18 years+ - NCT05091112Recruiting
Study of nerves during low back surgery
This study looks at tiny nerves in the low back during planned lumbar spine surgery. It may help researchers better understand nerve pathways that contribute to low back pain and nerve-related symptoms.
Aberdeen, ScotlandAges 18 years+ - NCT06736106Recruiting
Spine surgery recovery markers study
This trial looks at how certain markers of bone and muscle health might predict complications after spinal surgery. It could help doctors better understand which patients are at risk and improve recovery.
BolognaAges 18 years+ - NCT03187535Recruiting
TEAS treatment to prevent nausea after spinal surgery
This trial studies whether TEAS (a noninvasive electrical stimulation you receive during surgery) can reduce nausea and vomiting after spinal surgery. You might benefit if you’re at risk of “PONV” (post-surgery nausea and vomiting) and can safely take part in an acupoint-based stimulation study.
Columbus, OhioAges 18 years+ - NCT05795478Recruiting
Oxycodone plus pregabalin for long-term pain after spinal surgery
This trial studies whether taking oxycodone together with pregabalin (both pain medicines) can reduce chronic pain that can linger after spinal surgery. If you qualify, you may be asked to rate your pain and complete questionnaires during recovery.
BeijingAges 18 years+ - NCT05959603RecruitingPhase 3
Vancomycin powder during spinal surgery to prevent infection
This Phase 3 trial tests whether placing vancomycin powder in the wound during spinal fusion surgery can lower the chance of a surgical site infection. You might qualify if you’re having a specific type of spinal surgery and meet safety criteria.
Petah TikvaAges 18–90 - NCT06284174Recruiting
Comparing two antiseptics for spinal surgery wound soaking
This trial compares two common antiseptics (povidone-iodine and chlorhexidine gluconate) to see which better reduces germs in spinal surgery wounds during the operation. If you are having lumbar spine surgery, this study may help determine the best way to prevent infections.
Tainan, TaiwanAges 18 years+ - NCT06357234RecruitingPhase 2
Aprepitant to prevent nausea after child scoliosis surgery
This trial tests if a drug called Aprepitant, given before surgery, can better prevent nausea and vomiting after scoliosis repair in children. It is for children aged 8 to 18 who are having spinal fusion surgery for a certain type of scoliosis.
Halifax, Nova ScotiaAges 8–19 - NCT07197710Recruiting
Imagined acupuncture for pain after spine surgery
This trial tests if imagining acupuncture, guided by a video, can help reduce pain after spinal surgery. It is for adults having their first spine surgery on one or two bones.
Boston, MassachusettsAges 18 years+ - NCT07421752Recruiting
Robot accuracy test in spinal surgery
This trial tests how accurately a robotic system helps place screws in the spine during surgery. It may benefit people who need spinal surgery that involves inserting pedicle screws.
AmiensAges 5 years+ - NCT07354412Enrolling by invitation
Can cannabis affect anesthesia and inflammation in spine surgery?
This study looks at how using cannabis before or during lumbar spine surgery might affect anesthesia and inflammation. It compares patients who have used cannabis to those who have not, to see if there are differences in pain, recovery, or side effects.
Columbia, MissouriAges 18 years+ - NCT07207187Enrolling by invitation
Long-term outcomes of the Karma fixation system
This study looks at how patients are doing one year or more after spinal surgery with the Karma Fixation System. It may help doctors understand the long-term safety and effectiveness of this treatment.
Gilbert, ArizonaAges 18 years+ - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT07661589Recruiting
Blood transfusion risks and cell saver in children's scoliosis surgery
This trial looks at how often blood transfusions are needed during scoliosis surgery in children and whether using a device that recycles lost blood (cell saver) can reduce that need.
TunisAges Up to 17 years - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT06818396Recruiting
Pain relief for hip surgery: comparing two methods
This study compares two ways to manage pain during hip surgery: a nerve block in the groin area versus a spinal medication. The goal is to find which approach offers better pain control with fewer side effects.
CairoAges 21 years+
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Common questions
- Are there clinical trials for spinal surgery?
- Yes. Clin2 currently lists 132 recruiting spinal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.