Clinical trials
Spinal Surgery clinical trials
Below are recruiting spinal surgery clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06491030RecruitingPhase 4
Brace use after spinal fusion for adults with spine curves
This trial tests whether wearing a back brace after surgery helps prevent problems at the top of a spinal fusion. It is for adults aged 30-75 having their first spine fusion from near the middle of the back down to the tailbone or pelvis.
Carmel, IndianaAges 30–75 - NCT05860673Recruiting
Minimally invasive vs standard surgery for adolescent scoliosis
This study compares a less invasive surgical approach with the usual back surgery for adolescent idiopathic scoliosis (a sideways spine curve that starts in the teen years). It aims to see which approach works better and is easier to recover from.
BolognaAges 12–25 - NCT06101108Recruiting
Early heart screening in back surgery patients
This trial checks people having back surgery for spinal stenosis to see if they have an early sign of heart amyloidosis (a protein buildup in the heart). The goal is to find this condition early so it can be treated before it causes problems.
BrugesAges 60 years+ - NCT05611775Recruiting
Spinal surgery patients tracked for daily activity after surgery
This trial follows adults who are getting a multi-level spinal deformity correction surgery with special pelvic attachment. It looks at how well you return to real-life function and activity after surgery using follow-up visits at Mayo Clinic.
Rochester, MinnesotaAges 18 years+ - NCT07586189Recruiting
Comparing two anesthesia methods for spine surgery
This study compares two different ways doctors can put patients to sleep for spine surgery and measures how the patient's heart and blood pressure respond. The goal is to see which method is safer and more stable during surgery.
IstanbulAges 18 years+ - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT07217873RecruitingPhase 2/Phase 3
IV iron for teens with scoliosis and low iron
This trial tests whether giving intravenous (IV) iron before spine surgery helps teens with scoliosis who have low iron stores. The goal is to see if it can reduce the need for blood transfusions during surgery.
New York, New YorkAges 10–19 - NCT02610855Enrolling by invitation
Study of activity and muscle function in children with scoliosis
This study looks at how children’s activity levels and muscle performance change in different scoliosis treatments (surgery, bracing, or healthy peers). It uses motion sensors and an ultrasound-based test to better understand what treatments may do to the body’s muscles.
Rochester, MinnesotaAges 9–16 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT04888104Recruiting
Testing a spine implant to prevent failure near the top
This study looks at whether using a specific attachment system (VersaTie) with pedicle screws can help prevent problems near the top of a long spinal fusion. It compares outcomes in adults who are planning long posterior spine fusion surgery using this approach.
Phoenix, ArizonaAges 18 years+ - NCT07520487Recruiting
Ketamine Plus Spinal Anesthesia for Older Adults Undergoing Leg Surgery
This study tests whether adding ketamine (a type of anesthetic medication) to spinal anesthesia—numbing medication injected near the spine—can make the numbness last longer for older adults having leg surgery. The goal is to see if this combination improves pain control after surgery.
Cairo, Giza GovernorateAges 65 years+ - NCT05856539Recruiting
Numbing nerve block during minimally invasive low back surgery
This trial tests whether an “ESP block” (a numbing injection near the spine) can help control pain during minimally invasive low back fusion surgery. If you’re having this surgery, the goal is to improve comfort and reduce pain medicine needs.
New York, New YorkAges 18–80 - NCT04467944Recruiting
Lumbar fusion outcomes with arthritis in nearby spine segments
This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.
Beijing, Beijing MunicipalityAges 18–80 - NCT04855838Recruiting
Study of swallowing problems after neck spine surgery
This study looks at how swallowing recovers after surgery on the front of the neck spine after a trauma. Some people may also be followed more closely if a swallowing test shows a problem a few weeks after surgery.
UmeåAges 18 years+ - NCT05306665Recruiting
Preventing pain after spine surgery
This study looks at ways to reduce pain after certain spine surgeries. If you’re having one of these procedures, you may be invited to try a pain-prevention approach and help researchers understand what works best.
Chestnut Hill, MassachusettsAges 22 years+ - NCT05963815Recruiting
Spine surgery follow-up using online patient-reported questionnaires
This study looks at recovery after planned (elective) surgery for common lower-back (“lumbar”) spine problems like slipped discs, disc bulges, and narrowing of the spinal canal. You may be asked to complete online questionnaires, and the study uses your answers to understand symptoms and outcomes after surgery.
Rotterdam, South HollandAges 18–80 - NCT07348419Recruiting
Pain blocks after single-level lumbar disc surgery
This study compares two types of pain-blocking injections (Quadro-Iliac vs Thoracolumbar Interfascial Plane Block) to see which provides better pain relief after a single-level lumbar disc surgery. If you are having this surgery, the trial may help you have less pain and use fewer pain medicines afterwards.
SamsunAges 18–70 - NCT07561827RecruitingPhase 3
Nerve Block for Pain After Spine Surgery in Teens
This trial tests whether a numbing injection around the spine muscles (erector spinae plane block) reduces pain and the need for strong pain medications after back surgery for scoliosis in teenagers. The goal is to help young patients recover more comfortably.
San Francisco, CaliforniaAges 10–18 - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT05638191Recruiting
Nerve transfer surgery for arm grasp after neck spinal cord injury
This study looks at whether nerve transfer surgery can help restore hand grasp function after a neck (cervical) spinal cord injury. You may be eligible if your injury is recent and you meet specific strength patterns and can commit to rehabilitation after surgery.
Vancouver, British ColumbiaAges 18–70 - NCT07047469Recruiting
Ultrasound-guided spinal anesthesia in orthopedic surgery
This study compares two ways of giving spinal anesthesia (midline vs. paramedian) using ultrasound guidance in adults having orthopedic surgery. The goal is to see which approach is safer and more effective.
SohagAges 18–50 - NCT05527145Recruiting
Non-surgical spacer for spinal stenosis causing leg pain
This trial tests a minimally invasive (“through the skin”) procedure that places a small spacer between back bones to relieve lumbar spinal stenosis symptoms like leg pain when walking. It may help people who still need surgery based on their symptoms and MRI findings but may be treated without open surgery.
RomeAges 50–85 - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for spinal surgery?
- Yes. Clin2 currently lists 132 recruiting spinal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.