Clinical trials
Structural Heart Disease clinical trials
Below are recruiting structural heart disease clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT06977139Recruiting
Structural Heart Disease Registry Study in Lubeck
This study collects information from people with structural heart disease to learn more about their condition and treatments. It does not test a new drug or procedure—just observes your regular care.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06462989Enrolling by invitation
AI ECG for quick heart problem detection
This trial uses an AI tool called DeepECG to analyze ECG (heart electrical activity) recordings to quickly identify hidden heart problems. It helps doctors spot structural heart disease faster and guide you to the right care.
Montreal, QuebecAges 18 years+ - NCT05573997Recruiting
Testing new ultrasound measures of heart muscle function in heart failure
This study looks at whether a special kind of heart ultrasound can better measure how well the heart muscle works in people admitted with heart failure. It may help doctors understand heart function using clearer ultrasound “biomarkers” soon after hospital admission.
Thessaloniki, Central MacedoniaAges 18 years+ - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06260059RecruitingPhase 4
Jardiance for adults with congenital heart disease and reduced heart function
This study tests a medicine called Jardiance (an SGLT2 inhibitor) to see if it helps improve heart function in adults with congenital heart disease who have recently experienced a drop in their heart pumping ability. Participants will take the medication alongside standard heart failure treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06433401Recruiting
Structured transition care for teens with heart disease
This study tests a structured transition care model to help teenagers with congenital heart disease move from pediatric to adult care. It aims to make the process smoother and improve your health outcomes.
Ankara, Ankara YenimahalleAges 16–20 - NCT06590467Recruiting
Abbott heart device registry study
This registry is a large, ongoing study that collects information about Abbott heart devices used in routine care. It helps doctors learn how well these devices work and how patients are doing over time, without changing your treatment plan.
New Brunswick, New JerseyAges Any age - NCT06494163Recruiting
Exercise Training for Women With Heart Disease
This study compares two types of exercise training (high-intensity interval training vs. moderate-intensity continuous training) to see which is better for women with heart disease. You would be assigned randomly to one of the two exercise programs, and the study would last about 6 months.
Ottawa, OntarioAges 18 years+ - NCT06937983Recruiting
Mapping to guide heart rhythm treatment
This study tests a new way of mapping damaged heart muscle to improve the precision of a procedure called catheter ablation, which treats dangerously fast heart rhythms. It may help people with heart disease who need this procedure.
Coventry, West MidlandsAges 18 years+ - NCT07112391Recruiting
Pressure volume loop study for valve disease
This trial uses a special heart test called pressure volume loop assessment to better understand how well your heart pumps when you have severe valve disease. It aims to find patterns that may help doctors treat you more effectively. You may join if you have certain types of severe heart valve problems.
Nantes, Loire AtlantiqueAges 18 years+ - NCT07367893Recruiting
Exercise echocardiogram registry for heart disease
This study is creating a registry (a database) of patients who have an exercise echocardiogram, which is a stress test that uses ultrasound to look at your heart during exercise. It aims to better understand and diagnose different types of heart disease.
Yongin, Gyeonggi-doAges 18 years+ - NCT07033676Enrolling by invitation
Study of a blood marker for heart damage from high blood pressure
This trial looks at a substance in your blood called miR-455-5p to see if it can help doctors understand heart changes caused by high blood pressure. It involves people who have had high blood pressure for over a year and may have some heart symptoms.
Shenzhen, GuangdongAges 18 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT06015191Recruiting
Remote heart rehab for teens with congenital heart disease
This trial tests a home-based cardiac rehab program for adolescents with certain types of congenital heart disease. It aims to help you exercise safely and improve your fitness using online coaching and monitoring.
Kansas City, MissouriAges 12–19 - NCT07154355Recruiting
Community exercise for heart and lung patients
This study tests whether a community exercise program can improve health in people with heart or lung problems. It may help if you are not already doing regular, structured exercise.
Guangzhou, GuangdongAges 18–85 - NCT05552352Recruiting
VR training to help people prepare for aortic valve procedure
This trial tests whether virtual reality (VR) support helps patients feel more informed and prepared for an elective heart valve procedure (TAVI). It’s meant for people who already plan to have a valve replacement through the groin using a catheter, with pain medicines rather than full anesthesia.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06749951Recruiting
Talk therapy for insomnia in heart disease patients
This study tests whether cognitive behavioral therapy (a type of talk therapy focused on changing thoughts and habits) can help people with coronary heart disease who also have trouble sleeping. You will learn skills to improve your sleep and your overall heart health.
Drammen, BuskerudAges 18–75 - NCT06690684Enrolling by invitation
Finding new blood markers for heart disease
This study is looking for people who have had a heart attack or have heart failure to discover new markers in your blood that could help doctors better understand and treat heart disease. By collecting samples and health data, researchers hope to find clues that improve care for future patients.
Shanghai, Jing 'an DistrictAges 30 years+ - NCT07759427Recruiting
Using a new mapping method to guide treatment for fast heartbeats after a heart attack
This study tests a new way to find the exact spot in the heart that causes rapid heartbeats, so doctors can treat it more precisely with a procedure called catheter ablation.
BrightonAges 18 years+ - NCT07149701Recruiting
Ventricular Tachycardia patient registry study
This study is for adults with ventricular tachycardia (a fast heart rhythm) who also have structural heart disease. It will track your health over time to learn more about how this condition is managed.
BeijingAges 18 years+ - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT06360939Recruiting
Radiation or ablation for ventricular tachycardia in heart disease
This trial compares two treatments—radiation therapy or catheter ablation—for people with structural heart disease who have a type of fast heart rhythm called ventricular tachycardia. It aims to see which approach works better to prevent repeat episodes.
WestmeadAges 18 years+
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Common questions
- Are there clinical trials for structural heart disease?
- Yes. Clin2 currently lists 77 recruiting structural heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a structural heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a structural heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.