Clinical trials
Supplementation clinical trials
Below are recruiting supplementation clinical trials, each written for real people, not researchers. We’re tracking 692 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT07216755Recruiting
Breathing training and nitrate for altitude exercise
This study tests whether breathing training and a natural nitrate supplement (from beets) can improve how well you exercise in conditions that simulate high altitude. You'll do cycling workouts while we measure your performance.
Daytona Beach, FloridaAges 18–40 - NCT07241221Recruiting
Myo-inositol supplement for diabetes in pregnancy
This study tests whether taking a supplement called myo-inositol (a natural vitamin-like substance) during pregnancy can help manage blood sugar in women with type 2 diabetes. It may improve outcomes for you and your baby.
Singapore, SingaporeAges 21–45 - NCT07251244Recruiting
Supplement and exercise for immune health in older adults
This trial tests whether a combination of a supplement and moderate exercise can help keep your immune system strong and healthy as you age. It is for older adults who are independent and generally healthy.
Valencia, ValenciaAges 65 years+ - NCT07252778RecruitingPhase 2/Phase 3
Probiotics for endurance athletes
This trial tests if taking a probiotic supplement for a short time can help athletes who do endurance sports like rowing. If you are a healthy athlete on a national team, this study might help you understand how probiotics affect performance.
Poznan, WielkopolskaAges 16–50 - NCT07380022Recruiting
Iron and zinc supplements for adults with chronic diseases
This study tests whether two dietary supplements can improve iron and zinc levels in adults with Crohn's disease, ulcerative colitis, hypertension, anemia, or multiple sclerosis. It aims to see if patients find them easy to take and if they help the body absorb these minerals better.
Trikala, ThessalyAges 18 years+ - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT07583407Recruiting
How kava and kratom affect the body when taken alone or together
This study measures how your body processes kava and kratom—two plant-based products—when you take them separately or mixed together. The researchers want to understand their safety and how they interact in the body.
Guelph, OntarioAges 21–55 - NCT07600008RecruitingEarly Phase 1
Probiotics as a supplement for reflux disease management
This early-stage trial tests whether a probiotic supplement can help support treatment of reflux disease (GERD) in patients already taking a standard reflux medication. Researchers want to see if adding probiotics might improve symptoms or overall digestive health.
OlomoucAges 40–55 - NCT07625202Recruiting
Creatine Supplements During GLP-1 Weight-Loss Therapy
This trial tests whether adding creatine (a natural muscle-building supplement) helps preserve muscle and strength while taking GLP-1 medications like Ozempic or Wegovy. These medications help with weight loss but can sometimes cause muscle loss, so researchers want to see if creatine prevents that.
Saskatoon, SK - SaskatchewanAges 18 years+ - NCT07000500Enrolling by invitation
Nutritional supplement for memory decline in older adults
This trial tests whether a nutritional supplement can help slow or improve memory loss in older adults who have mild cognitive decline (noticeable changes in thinking skills that are not yet dementia). You will take a daily supplement and attend regular check-ups.
Vila Nova de Famalicão, Braga DistrictAges 65 years+ - NCT05097365Enrolling by invitation
Testing a methyl-donor supplement to study lupus metabolism
This study looks at whether a “methyl-donor” nutrient supplement changes metabolism (methylation) in people with lupus who are also in the childbearing age range and have low-to-moderate disease activity. It may help researchers understand why lupus acts differently in some people and how diet-related pathways could affect symptoms.
São PauloAges 18–45 - NCT07777328Recruiting
5-HTP for ADHD traits and eye movements in adults
This study looks at how a supplement called 5-HTP (a natural amino acid) affects attention and eye movements in adults. You will receive either 5-HTP or a placebo to see if it changes ADHD-like traits.
Sheffield, South YorkshireAges 18–65 - NCT07774520RecruitingPhase 2
Lower dose of lazertinib plus magnesium to prevent nerve damage in advanced lung cancer
This trial tests a lower starting dose of the targeted therapy drug lazertinib combined with magnesium supplements to prevent a common side effect (peripheral neuropathy) in people with advanced lung cancer caused by certain EGFR mutations. The goal is to see if this approach keeps the drug effective while reducing nerve damage symptoms like numbness or tingling.
Seoul, Gang-nam GuAges 19 years+ - NCT07766980Recruiting
Nutritional supplement for quality of life in Duchenne muscular dystrophy
This study tests whether a daily nutritional supplement called VM100 can improve quality of life for people with Duchenne muscular dystrophy. If you are 8 or older and your medications have been stable for at least 3 months, you may be able to participate.
Gainesville, FloridaAges 6 years+ - NCT07768423Recruiting
Omega-3 supplements and red blood cell health in soccer players
This study looks at how taking omega-3 supplements (from fish oil) affects the red blood cells of soccer players. It might help improve their overall health and performance.
Katowice, Mikolowska 72aAges 16–35 - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT07115563Recruiting
Amino acid supplement test for Parkinson's disease
This trial tests if taking daily amino acid supplements helps people with Parkinson's disease. You need to be on stable Parkinson's medication for at least 3 months.
Farmington, ConnecticutAges 50–90 - NCT07760493Enrolling by invitation
Zinc supplements before and after colon surgery in children
This study is testing whether giving children zinc supplements around the time of colon surgery helps them recover faster and have fewer problems. It may help their body heal better after the operation.
Alexandria, Alexandria GovernorateAges 1 month–18 years - NCT07156552Recruiting
Protein and exercise to prevent muscle loss after weight loss surgery
This trial tests whether taking extra protein and doing resistance training helps people keep their muscle mass after bariatric surgery (stomach reduction or gastric bypass). If you're scheduled for this surgery and can follow the program, you may be able to join.
AmsterdamAges 18 years+ - NCT07341399Enrolling by invitation
Amino acid supplement study for spinal deformity surgery
This trial tests whether taking essential amino acid supplements before and after surgery can help adults recovering from spinal deformity correction. It is for patients who are scheduled for surgery at UAMS and will attend physical therapy in Little Rock.
Little Rock, ArkansasAges 40–65 - NCT07755943Recruiting
Long-term supplement use and biological age
This study looks at whether taking Shaklee supplements for more than a year is linked to a younger biological age and better metabolic health. If you're 40 or older and have been using these supplements long-term, your participation could help understand their potential benefits.
Addison, IllinoisAges 40 years+ - NCT06837246Recruiting
Nutritional supplement study for cognitive health in adults
This study tests whether a nutritional supplement taken as 3 capsules daily for 12 weeks can improve cognitive function. It is designed for generally healthy adults who do not have certain medical conditions or take certain medications.
Addison, IllinoisAges 25–65 - NCT07753174Recruiting
Omega-3 supplement study for healthy adults
This study tests a supplement containing omega-3 fats to see how it affects levels of DHA and EPA in your blood. If you're a healthy adult, you might join to help learn if this supplement can boost these important fats.
Las Vegas, NevadaAges 18–65
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Common questions
- Are there clinical trials for supplementation?
- Yes. Clin2 currently lists 692 recruiting supplementation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a supplementation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a supplementation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.