Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 931 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT06413849Recruiting
Phone coaching with a picture-story book for dementia caregivers
This study tests if talking with a coach by phone and reading a story-based book can help family caregivers of people with dementia feel better. You'll get a free book and weekly coaching calls to help manage your mood.
Hong Kong SARAges 18 years+ - NCT06250582Recruiting
Can Virtual Reality Reduce Symptoms During Dialysis?
This study tests whether using virtual reality can help reduce symptoms (like fatigue, pain, or anxiety) during dialysis. You would use a VR headset during your regular dialysis sessions and report how you feel.
Zurich, Canton of ZurichAges 18 years+ - NCT06287970Recruiting
Testing a nerve stimulation device for chronic pelvic pain
This trial tests if a non-invasive nerve stimulation device (TaVNS) can reduce pain, urinary symptoms, and mood issues in men with moderate to severe chronic pelvic pain syndrome (CP/CPPS). It may offer a new drug-free option for symptom relief.
Beijing, Beijing MunicipalityAges 18–50 - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT07278973Recruiting
Dialysis study for people over 84 with kidney failure
This trial compares two types of dialysis (hemodiafiltration and standard hemodialysis) to see which works better for older adults with kidney failure. You may be eligible if you are over 84, have been on dialysis for at least 3 months, and are generally healthy enough to participate.
BretagneAges 85 years+ - NCT06653426Recruiting
The effect of NaBu on menstrual symptoms
This study tests whether taking a supplement called NaBu can help reduce menstrual symptoms. It may be an option if you have bothersome period symptoms like cramps or bloating.
Chicago, IllinoisAges 18 years+ - NCT06658041Recruiting
A step-by-step program for mild to moderate depression
This trial tests a structured support program for adults with mild to moderate depression. It uses a team-based approach in primary care to help you feel better step by step.
Hong Kong, HONG KONGAges 45–59 - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT07453823Recruiting
Synbiotic for gut health in overweight adults
This trial tests a combination supplement (a synbiotic) to see if it can improve gut function and gut bacteria in middle-aged and older adults who are overweight and have constipation. If eligible, you take the supplement daily and report how your digestion feels.
Cork, BlackpoolAges 50–70 - NCT07228806Recruiting
Telerehabilitation for pelvic floor health after childbirth
This trial tests whether physical therapy done remotely (telerehabilitation) can help strengthen the pelvic floor muscles after childbirth. It is for women who had their first baby and a vaginal delivery, and who are at least 6 weeks postpartum.
Ankara, YenimahalleAges 18–45 - NCT07063576RecruitingPhase 2/Phase 3
Baclofen for persistent heartburn or regurgitation
This trial tests whether the drug baclofen can help patients who still have acid reflux symptoms (heartburn or regurgitation) despite taking standard treatments like PPIs for 8 weeks. If you've tried PPIs and still have symptoms, this may be an option.
DhakaAges 18 years+ - NCT06716554Recruiting
Shatavari for menopausal symptoms in women
This study tests whether a natural herb called Shatavari can help with menopausal symptoms like hot flashes, sleep problems, and mood changes. It compares Shatavari to a placebo (a pill with no active ingredient) to see if it is safe and effective.
San Francisco, CaliforniaAges 45–55 - NCT07562386Recruiting
Prostate Surgery Outcomes and Patient Satisfaction Study
This study compares two surgical techniques for enlarged prostate (benign prostatic hyperplasia, or BPH) to see which one works better and how satisfied patients are afterward. If you have moderate prostate enlargement and urinary symptoms, this trial might help improve your treatment.
HamarAges Up to 80 years - NCT07196189Recruiting
Fecal transplant for eating disorders
This study tests whether a fecal microbiota transplant (transferring healthy donor stool into your gut) can help treat eating disorders like anorexia, bulimia, or binge eating disorder. It is for women ages 18 to 50 who have not had antibiotics in the last 3 months.
RouenAges 18–50 - NCT07580118Recruiting
Postbiotic Supplement Study for Female Athletes
This study tests whether a postbiotic supplement (a type of gut health product) can reduce digestive problems that female athletes experience during exercise and their menstrual cycle. You'll take the supplement for several months while tracking your symptoms and training.
Liverpool, MerseysideAges 18 years+ - NCT05784428Recruiting
Radiation “spot treatments” for a few metastatic or worsening spots
This trial compares giving stereotactic ablative radiotherapy as one larger treatment plan versus several smaller plans for people who have only a few cancer spots (or a few spots that are worsening). It may help control metastatic disease while aiming to protect surrounding healthy organs.
Kelowna, British ColumbiaAges 18 years+ - NCT06709534Recruiting
Exercise program for gynecologic cancer survivors
This study tests a personalized at-home exercise program designed for gynecologic cancer survivors who have finished treatment. The goal is to see if it can help you feel better and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT07556718RecruitingPhase 2
Amitriptyline for IBS-like Symptoms in Stable Crohn's Disease
This study tests whether a medication called amitriptyline can help reduce belly pain and bowel problems in people whose Crohn's disease is well-controlled. Amitriptyline is an older antidepressant that may help with pain and bowel symptoms even when inflammation is quiet.
Ann Arbor, MichiganAges 18–65 - NCT06075316Recruiting
Tracking recovery after chest surgery using patient check-ins
This study tests a simple way to track your recovery after major chest surgery by checking in with you through a phone call or online survey. You'll help doctors see how you're doing and improve care for future patients.
Chapel Hill, North CarolinaAges 18–99 - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17 - NCT07386249Recruiting
Wheat lipid cream for vaginal dryness in postmenopausal women
This trial tests a cream made from wheat polar lipids to see if it helps with vaginal dryness after menopause. It may offer a non-hormonal option for women with moderate to severe discomfort.
Louvain-la-Neuve, BelgiumAges 45–65 - NCT07083596Recruiting
Fermented milk drink for constipation relief in Filipino adults
This study tests if a special fermented milk drink can help relieve constipation symptoms like hard or lumpy stools. Researchers want to see if it works for adults who have constipation without a known medical cause.
Manila, ManilaAges 18–59 - NCT06419972Recruiting
Multimodal program for women in menopause transition
This study tests a program combining different therapies to help women during the menopause transition. It aims to improve symptoms and quality of life.
ValenciaAges 45–85
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 931 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.