Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 940 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests a medication called fezolinetant to see if it reduces hot flashes in men undergoing hormone therapy for prostate cancer. If you experience frequent hot flashes, this treatment might help alleviate them.
Boston, MassachusettsAges 40 years+ - NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT07646509Recruiting
Mobile app to reduce physical symptoms from stress
This study tests a smartphone app designed to help people with somatic symptom disorder—a condition where stress and emotional distress cause ongoing physical symptoms that don't have a clear medical explanation. The app sends you check-ins and guidance throughout your day to help reduce these symptoms.
Vienna, State of ViennaAges 18–65 - NCT07415564Recruiting
Support program for advanced cancer patients and their caregivers
This trial offers coaching and symptom management support for people with advanced breast, GI, or melanoma cancer and their caregivers. The goal is to improve quality of life for both.
Tucson, ArizonaAges 18 years+ - NCT06163014Recruiting
Managing persistent symptoms with online help and GP support
This trial tests a program that combines online tools with help from your GP to manage symptoms that have lasted a while. It aims to see if this approach helps people feel better and understand their symptoms.
AarhusAges 18–65 - NCT06396312Recruiting
Predicting lithium response in difficult depression
This study looks at how to predict which people with hard-to-treat depression will benefit from adding lithium to their antidepressant. If you have treatment-resistant depression and are considering lithium, this trial may help find the best treatment for you.
Munich, BavariaAges 18 years+ - NCT07281300Recruiting
Mindfulness for breathing distress in lung cancer
This trial tests a mindfulness-based program to help lung cancer patients manage breathing difficulty and other symptoms. It aims to reduce distress and improve daily life.
Hong KongAges 18 years+ - NCT02421705Recruiting
Brain-gut sensitivity study in IBS and inflammatory bowel disease
This study checks how sensitive your gut is to normal stimuli in people with IBS, ulcerative colitis, Crohn’s disease, and in healthy volunteers. Results may help researchers understand why some people feel more abdominal discomfort and how that connects to inflammatory bowel conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT06648928Enrolling by invitation
App for reducing PTSD in Florida 9/11 responders
This study is testing a mobile app called PTSD Coach, along with support from a clinician, to help World Trade Center responders in Florida reduce symptoms of post-traumatic stress. It may be a good fit if you have some PTSD symptoms but not severe alcohol or drug use, and you are not already receiving PTSD treatment.
Miami, FloridaAges Any age - NCT06127004Recruiting
Metacognitive training for negative symptoms
This study tests a training program designed to help people with schizophrenia or related conditions better manage challenging thoughts and feelings. It may be a good fit if you have trouble with motivation, social withdrawal, or low energy (negative symptoms).
Multiple LocationsAges 18 years+ - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT05748210Recruiting
App to help children’s cancer after-treatment symptoms
This study tests a smartphone/tablet app that helps children who have finished cancer treatment and their caregivers manage early symptoms that may come back after treatment. It may help families track symptoms and get supportive guidance during the early survivorship period.
Hong KongAges 9–16 - NCT05958316Recruiting
Tool to help teens and young adults manage cancer symptoms
This study tests a practical check-in tool that helps adolescents and young adults track and manage symptoms from cancer or cancer treatment. It may help you better handle symptoms day to day during ongoing treatment.
Kansas City, MissouriAges 15–29 - NCT06012903Recruiting
Bladder symptoms and school performance in children
This study looks at how lower urinary tract symptoms (like frequent bathroom trips or accidents) affect children's daily life and schoolwork. It aims to understand these challenges from the child's, parent's, and teacher's point of view.
Ghent, East FlandersAges 5–12 - NCT06257134Recruiting
Monitoring symptoms to improve quality of life in dialysis patients
This trial tests if regularly tracking symptoms through an electronic system can improve quality of life for people on dialysis. It aims to help patients and their care teams better manage symptoms.
GradignanAges 18 years+ - NCT06278532Recruiting
Validating psychosis assessment tools in Lithuanian
This trial tests whether three psychiatric questionnaires work well for people with schizophrenia or related disorders. If you are between 18 and 65 and have one of these diagnoses, joining may help improve care for others like you.
KaunasAges 18–65 - NCT06311110Recruiting
Toilet training and bladder issues in children with DCD
This study looks at how Developmental Coordination Disorder (DCD) affects toilet training, bladder, and bowel function in children. It compares children with DCD to those with typical development to identify differences and problems.
Ghent, East FlandersAges 5–8 - NCT06582173Recruiting
Mapping healthcare paths for teens with physical symptoms linked to stress
This study maps how 12–25 year olds with somatic symptom disorder (physical symptoms caused by stress or emotions) get diagnosed and treated. It aims to improve care by understanding the best ways to evaluate and support these young people and their families.
Paris, IDFAges 12 years+ - NCT06975280Recruiting
PTSD therapy for unaccompanied refugee teens in Greece
This study tests a talking therapy (Trauma-Focused Cognitive Behavioral Therapy) to help unaccompanied refugee minors aged 15-18 who have PTSD or stress symptoms from trauma. It aims to see if the therapy reduces distress and helps them feel better.
AthensAges 15–18 - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT07476469Recruiting
Nerve stimulation for anhedonia and anxiety
This study tests whether a gentle nerve stimulation device (tVNS) placed on your ear can help reduce symptoms of anhedonia (loss of pleasure) and anxiety. You will also have brain scans (MRI) to see how the treatment affects your brain.
BonnAges 18–40 - NCT07617922RecruitingPhase 2
Melatonin and solifenacin for ureteral stent discomfort
This study tests whether two medications—melatonin (a sleep aid) and solifenacin (a bladder-control medicine)—can reduce uncomfortable symptoms from a temporary plastic tube (ureteral stent) placed in your urinary system during kidney stone treatment. The goal is to find out if these drugs help you feel better while the stent is in place.
Banī Suwayf, BeniSuefAges 18–60 - NCT06649201Recruiting
Study of vaginal health after stem cell transplant
This study looks at how stem cell transplants affect the vagina, especially if you develop a condition called graft-versus-host disease (GVHD). Researchers will examine the vagina and test its natural germs (microbiome) to better understand and possibly improve treatment.
Cleveland, OhioAges 18–70 - NCT07769931Recruiting
Pecha Kucha learning for chemotherapy side effects
This study tests a teaching session about managing chemotherapy symptoms and improving quality of life. It is designed to help you feel more in control of your treatment side effects.
IstanbulAges 18 years+
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 940 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.