Clinical trials
TAVI clinical trials
Below are recruiting tavi clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06833762Recruiting
Predicting improvement after TAVI using exercise tests
This trial looks at whether a simple exercise test (called CPET) can help predict how much your heart function will improve after TAVI, a procedure to replace a narrowed heart valve. If you're scheduled for TAVI through your leg artery and are 18 or older, you might be able to join.
BarcelonaAges 18 years+ - NCT05283356RecruitingPhase 4
Ticagrelor or aspirin after heart valve replacement
This trial compares two blood thinners (ticagrelor and aspirin) to see which one works better at preventing blood clots after a less-invasive heart valve replacement (TAVI). It is for people with severe aortic stenosis who also have diabetes, heart disease, or artery disease.
Vigo, PontevedraAges 18 years+ - NCT07456280Recruiting
Early discharge after TAVI using heart monitoring
This study tests if patients who have mild heart electrical changes after TAVI can be sent home early with a portable heart monitor instead of staying in the hospital. It aims to see if this approach is safe and effective.
BarcelonaAges 18 years+ - NCT03192774Recruiting
Prospective heart valve treatment registry for TAVI patients
This study is a real-world registry that collects information from people who receive TAVI, a procedure to treat a damaged heart valve. It may help doctors understand outcomes and improve care, even though it isn’t testing a new drug.
Bad SegebergAges 18–100 - NCT04029844Recruiting
Transcatheter valve replacement for older adults with severe aortic stenosis
This study tests a new “through-a-vein” heart valve procedure for people age 75+ with severe aortic valve narrowing that causes symptoms. It aims to see if the new valve can be safely implanted and improve outcomes in higher-surgery-risk patients.
LilleAges 75 years+ - NCT05015452Recruiting
Registry for people who get TAVI
This is a patient registry that collects information from people who receive TAVI, a procedure used to treat certain heart valve problems. It may help doctors better understand who benefits and how patients do over time.
LeipzigAges 18 years+ - NCT05133843Recruiting
Test heart blood-flow measurements before and after TAVI
This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.
LeipzigAges 18 years+ - NCT05235555Recruiting
TAVI registry for people with severe aortic valve disease
This registry follows people with severe aortic valve narrowing (and sometimes a worn-out valve) who are considered good candidates for TAVI, a valve-replacement procedure. It helps doctors better understand outcomes and care over time.
NaplesAges 55–100 - NCT05758662Recruiting
PET-CT and heart ultrasound study valve changes after TAVI
This study looks at whether certain valve blood clots (called “subclinical leaflet thrombosis”) and different valve types are linked to valve aging over time. It uses a special PET-CT scan and an echocardiogram to measure changes in the heart valve about five years after TAVI.
CopenhagenAges 18 years+ - NCT05909748Recruiting
First-in-human test of a new TAVR valve for severe aortic narrowing
This trial tests a new heart valve replacement (TAVR) system in people with severe, symptomatic aortic stenosis. If you qualify, it may offer a less invasive option compared with open-heart valve surgery, while also helping researchers understand safety and early effectiveness.
Petah TikvaAges 18–120 - NCT05966675Recruiting
Special heart pacing after TAVI to help protect heart function
This trial looks at a physiologic (more natural) heart pacing approach to prevent weakening of the heart’s main pumping chamber after TAVI. It enrolls people who recently had TAVI and now meet standard reasons for needing a permanent pacemaker.
KatowiceAges 18 years+ - NCT06007222RecruitingPhase 4
No blood thinners after TAVI: a trial for heart valve patients
This trial is for people who have had a TAVI procedure to replace a narrowed heart valve, and it tests whether it is safe to skip blood thinners afterward. The goal is to find the best way to protect your health without unnecessary medication.
Shinjuku, TokyoAges 20 years+ - NCT06049654Recruiting
Comparing Allegra and Sapien valves for valve-in-valve procedure
This trial tests two different replacement heart valves (Allegra and Sapien) to see which works better for people who need a new valve placed inside a previously implanted surgical valve. It aims to help patients with a failing biological aortic valve who are already scheduled for this procedure.
AlessandriaAges 18 years+ - NCT06197503Recruiting
Comparing two types of heart pacing after TAVI
This trial compares two ways to pace the heart after a TAVI procedure for people who need a pacemaker. It aims to find which pacing method works better for preserving heart function.
BarcelonaAges 18 years+ - NCT06215378RecruitingPhase 3
Protamine Sulfate to Reverse Heparin After TAVI
This trial tests whether giving protamine sulfate after a TAVI procedure (aortic valve replacement through the leg) to reverse the blood thinner heparin is safe and effective. It may help reduce bleeding risk for patients.
Paris, Île-de-France RegionAges 18 years+ - NCT06481137Recruiting
Can heart electrical problems after TAVI get better?
This study looks at whether electrical problems in the heart that appear after a TAVI valve replacement can go away on their own. It will help doctors decide which patients might need a pacemaker and which might get better without one.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT06508866Recruiting
Studying heart rhythm changes after TAVI procedure
This trial looks at how the heart's electrical system may change after TAVI, a procedure to replace a narrowed aortic valve. It aims to better understand these changes to improve care for future patients.
Rozzano, MilanoAges 18 years+ - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT06713889Recruiting
Study of heart valve disease and events
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
LyonAges 18 years+ - NCT06756282Recruiting
Pacemaker use one year after TAVR
This study looks at people who need a permanent pacemaker after having a TAVR procedure (a type of heart valve replacement). It aims to see how many people still need the pacemaker one year later.
MontpellierAges Any age - NCT06816485Recruiting
New balloon safety in TAVI for severe aortic stenosis
This trial studies a new balloon used during a TAVI procedure to replace your aortic valve without open-heart surgery. It aims to see if the balloon is safe and works well for people with severe aortic stenosis.
BarcelonaAges 18 years+ - NCT06818435Recruiting
Registry study of the Myval heart valve for severe aortic stenosis
This study is tracking how well the Myval valve works in people with severe aortic stenosis who get it through a minimally invasive procedure called TAVI. It helps doctors learn more about the valve's safety and performance in real-world use.
CarnaxideAges 18 years+ - NCT06962371Recruiting
A study testing a new device during TAVR heart valve replacement
This trial is testing a new device called POINT-GUARD that is used during TAVR (a procedure to replace a heart valve). It aims to see if the device can safely catch any debris or particles that might travel to the brain during the procedure.
Clayton, VictoriaAges 18 years+
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Common questions
- Are there clinical trials for tavi?
- Yes. Clin2 currently lists 65 recruiting tavi studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tavi trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tavi trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.