Clinical trials
Temporomandibular Disorder clinical trials
Below are recruiting temporomandibular disorder clinical trials, each written for real people, not researchers. We’re tracking 75 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06582134Recruiting
Mindfulness for jaw pain in university students
This trial tests whether brief mindfulness exercises can help reduce jaw pain in university students. If you have had jaw pain for at least 3 months, you may be able to join.
Kuala Lumpur, Kuala LumpurAges 18–30 - NCT05907239Recruiting
Shock wave therapy for jaw muscle pain
This trial tests whether focused shock wave treatment can reduce chronic jaw pain caused by jaw muscle problems. You might qualify if you have moderate to severe temporomandibular (jaw) pain for at least 3 months.
São Paulo, São PauloAges 18 years+ - NCT06977100Recruiting
Journaling study for jaw pain with other chronic pain conditions
This study tests if a journaling program can help people with jaw pain and at least one other chronic pain condition (like fibromyalgia, IBS, or migraines). You will write about your thoughts and feelings to see if it reduces pain and improves well-being.
Gainesville, FloridaAges 18–80 - NCT06721104Recruiting
Balance and jaw health in autism
This study looks at balance, jaw joint function, and social skills in people with autism. It aims to understand how these areas are connected and could help improve care.
KirikkaleAges 4–21 - NCT07373184Recruiting
Virtual planning for jaw joint replacement
This study looks back at past jaw joint (TMJ) replacement surgeries to see how virtual planning helped. If you already had this surgery at a specific hospital between 2010 and 2025, you might be included.
LundAges Any age - NCT07486609Enrolling by invitation
Comparing tests for jaw joint pain diagnosis
This study compares two different ways to diagnose jaw joint (TMJ) problems: a jaw-motion analyzer and an MRI. It aims to see which method is more accurate for people with ongoing face or jaw pain.
CairoAges 18–50 - NCT06627855Recruiting
Fascial stretch method for jaw pain relief
This study tests a hands-on technique called the fascial distortion model to see if it works better than a sham treatment for reducing jaw, face, or neck pain. It may help if you have had a jaw disorder for at least 3 months.
Merkez, Karabük ProvinceAges 18–64 - NCT06553950Recruiting
Splint vs botox for jaw and neck pain
This trial compares a custom jaw splint with botox injections to see which better reduces neck muscle tension in people with jaw joint problems. It's for patients who have a displaced jaw disc that still clicks or pops and also have neck muscle spasms.
CairoAges 18–40 - NCT06365151Recruiting
Jaw pain treatment in fibromyalgia
This study tests a gentle hands-on treatment (osteopathic manual therapy) for jaw pain or problems in people with fibromyalgia. The goal is to see if this approach can help ease jaw discomfort and improve function.
Cornellà de Llobregat, BarcelonaAges 18–75 - NCT06782165Recruiting
Long-term follow-up of jaw joint surgery
This study follows up on patients who had jaw joint (TMJ) surgery. It looks at how the joint is doing after 6 months to predict long-term results. It may help understand if earlier checkups can guide care.
HuddingeAges 18 years+ - NCT04831346Recruiting
Laser treatment to improve jaw opening in young women
This study tests whether low-level laser therapy can improve how far you can open your jaw and changes in jaw muscle activity in people with one-sided jaw muscle temporomandibular disorder (TMD). It may help reduce jaw movement limits related to that condition.
GizaAges 18–30 - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+ - NCT06694532RecruitingPhase 1/Phase 2
Arthrocentesis with hyaluronic acid for TMJ disorders
This trial tests two types of hyaluronic acid (high vs low molecular weight) given during a jaw joint procedure (arthrocentesis) to see which better relieves pain and improves jaw function in people with TMJ disorders.
AsyutAges 18–100 - NCT07129096Enrolling by invitation
Digital relaxation training for jaw pain
This study tests if a digital relaxation program can help reduce jaw pain caused by temporomandibular disorders (TMD). It may be a good option if you have jaw muscle or joint pain and want to try a non-drug approach.
OuluAges Any age - NCT07075276Recruiting
Comparing a new growth factor treatment to standard care for jaw joint pain
This study tests a new treatment for a common jaw joint problem called disc displacement. It compares a concentrated growth factor from your own blood to standard care to see which helps more with pain and jaw movement.
Damietta, New DamiettaAges 18–45 - NCT07576582Recruiting
Mud therapy for jaw joint pain
This trial tests whether a special mud treatment (peloid therapy) can reduce jaw joint pain and improve function in people with temporomandibular joint disorder. It is a non-drug approach that may help those who have had jaw pain for at least 4 weeks.
Uşak, MerkezAges 18–65 - NCT04214561Enrolling by invitation
Studies how sleep measures relate to teeth grinding
This study looks at sleep testing results to understand what relates to sleep bruxism, which is teeth grinding or clenching during sleep. It may help researchers better understand the causes and patterns behind this condition.
WroclawAges 18–70 - NCT05317390Recruiting
Tests an AI tool to diagnose isolated dystonia
This trial checks whether an AI (software) called DystoniaNet can accurately identify isolated dystonia using information from your evaluation, and compares its results to standard diagnosis. If you have focal, segmental, or generalized dystonia, this study may help improve faster and more accurate diagnosis in the future.
Boston, MassachusettsAges Any age - NCT06222736Recruiting
Cervical core exercises for jaw joint pain relief
This study tests whether exercises for the neck and upper back can reduce pain and improve function in women with jaw joint problems caused by muscle pain. It could help if you have jaw pain related to tense or sore muscles.
Istanbul, AvcılarAges 18 years+ - NCT03083405Enrolling by invitation
Study of tooth grinding during sleep
This study is for adults who have been diagnosed with sleep bruxism (tooth grinding during sleep). Researchers want to understand it better using sleep testing, and it may help refine how this condition is evaluated.
WroclawAges 18–70 - NCT05902026Enrolling by invitation
Questionnaire study for jaw-related headache and pain impact
This study tests a biopsychosocial questionnaire (a survey about thoughts, daily life, and pain) for people with jaw-related headaches from temporomandibular disorder (TMD). It may help researchers better understand what influences headache severity and how to support treatment planning.
Gaziantep, Hasan Kalyoncu UniversityAges 18–60 - NCT06782178Recruiting
Comparing two jaw joint procedures for limited mouth opening
This study compares two minimally invasive procedures (arthroscopy using a tiny camera vs. arthrocentesis using a needle to flush the joint) to see which works better for people with a displaced jaw disc that limits mouth opening. It might help you if simple treatments haven't worked.
HuddingeAges 18 years+ - NCT06782191Recruiting
Arthroscopic treatments for jaw joint disc displacement
This trial tests two types of jaw joint surgery for people with a displaced disc that still moves. It compares a simpler procedure (flushing the joint) with a more involved one (surgical repair) to see which helps more with pain and jaw function.
HuddingeAges 18 years+ - NCT06763419Recruiting
Light therapy for jaw joint pain
This trial tests if a non-invasive light therapy (photobiomodulation) can reduce pain and clicking in the jaw joint. It may help people with jaw pain caused by muscle tension or joint issues.
AlexandriaAges 20–40
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Common questions
- Are there clinical trials for temporomandibular disorder?
- Yes. Clin2 currently lists 75 recruiting temporomandibular disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a temporomandibular disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a temporomandibular disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Temporomandibular Disorders (TMD)
- Temporomandibular Joint Disorders
- Temporomandibular Disorders (TMDs)
- Temporomandibular Joint Dysfunction
- Temporomandibular Joint Dysfunction Syndrome
- Temporomandibular Dysfunction (TMD)
- Temporomandibular Joint Disc Displacement, Without Reduction
- Temporomandibular Joint and Muscle Disorder
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.