Clinical trials
Testicular Cancer clinical trials
Below are recruiting testicular cancer clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05588700Recruiting
Exercise program to reduce long-term cancer fatigue
This trial studies whether a structured physical activity program can reduce ongoing (long-term) fatigue in men with metastatic testicular cancer. It likely helps by improving fitness and energy during and after first-line chemotherapy.
AngersAges 18 years+ - NCT07258563Recruiting
Can a special diet prevent taste changes from chemo?
This study looks at whether a special diet can help prevent taste changes during chemotherapy. It is for people with certain cancers who are about to start treatment.
AmsterdamAges 18–70 - NCT02872532Recruiting
Freezing testicle tissue in children before cancer treatment
This trial studies how doctors collect and freeze a small piece of testicle tissue from boys to protect future fertility before treatments like chemotherapy or radiation. It may help families preserve options for having children later if testicular function is permanently affected.
Rochester, MinnesotaAges birth–17 years - NCT07407582RecruitingPhase 1/Phase 2
Sodium thiosulfate to protect hearing during cisplatin chemo
This trial tests whether a medicine called sodium thiosulfate can protect your hearing from the side effects of cisplatin chemotherapy. It is for people with newly diagnosed cancer who are about to receive cisplatin for the first time.
Tucson, ArizonaAges 18 years+ - NCT06063551Recruiting
Freezing testicular tissue to protect fertility in boys with cancer
This study freezes a small piece of testicular tissue from boys with cancer before they start treatment that could cause permanent infertility. The tissue is stored so that, in the future, it might help them have biological children.
Edinburgh, LothianAges 1 day–18 years - NCT05840575Recruiting
Study of thinking changes in young people during cancer treatment
This study looks at how thinking and memory may change in children and young adults after a new cancer diagnosis, especially around chemotherapy. It may help doctors better understand and track brain-related side effects early.
CopenhagenAges 7–29 - NCT02229916Recruiting
Follow-up study for testicular cancer after recent treatment
This study looks at how people with testicular cancer are doing after finishing treatment. It mainly focuses on follow-up visits (surveillance) and whether you are in remission, which can help doctors understand and improve post-treatment care.
Sankt GallenAges 18 years+ - NCT06932458RecruitingPhase 2
Surgery for seminoma that has spread to lymph nodes
This trial tests if removing the involved lymph nodes in the abdomen (retroperitoneal lymph node dissection) is a good treatment for seminoma that has spread to a small number of lymph nodes. It may help patients avoid more chemotherapy or radiation.
London, OntarioAges 18 years+ - NCT02972801Recruiting
Freezing testicle tissue to protect future fertility
This study helps collect and freeze testicle tissue for people who must have surgery, chemotherapy, medicines, or radiation that could permanently harm fertility. You may join if you’re newly diagnosed or need planned treatment that threatens testicular function, and you agree to long-term follow-up.
Pittsburgh, PennsylvaniaAges Any age - NCT05414045Recruiting
Transplanting your own frozen testicle tissue for future fertility
This trial studies transplanting frozen testicular tissue back into the body to help restore fertility later. It is meant for people who preserved testicular tissue as children before cancer or a blood disorder treatment.
BrusselsAges 18–50 - NCT06620016Recruiting
MicroRNA study for small testicular or post-chemo masses
This study looks at tiny molecules called microRNAs in the blood of people with either small testicular tumors (less than 2 cm) or leftover lymph node masses after chemotherapy for testicular cancer. The goal is to see if these microRNAs can help guide treatment decisions.
BolognaAges 18 years+ - NCT06276491RecruitingPhase 1
Safety study of an investigational drug for advanced cancer with the CLDN6 marker
This trial tests an investigational drug for people with advanced solid tumors, especially ovarian, fallopian tube, peritoneal, endometrial, or germ cell cancers that have a specific marker called CLDN6. The goal is to see if the drug is safe and tolerable.
Duarte, CaliforniaAges 15 years+ - NCT06866964RecruitingPhase 2
Aspirin to prevent blood clots in advanced germ cell cancer chemotherapy
This trial tests if daily aspirin can prevent dangerous blood clots in people receiving chemotherapy for advanced testicular or germ cell cancer. It is for those at high risk of clots and aims to improve safety during treatment.
Charlotte, North CarolinaAges 18–70 - NCT06828185Recruiting
Comparing two surgery methods for testicular cancer
This trial compares two ways of doing surgery (radical orchiectomy) for testicular cancer. One method is the standard approach and the other spares a layer of muscle tissue. The study looks at patient experiences and recovery.
Loma Linda, CaliforniaAges 18 years+ - NCT06593665RecruitingPhase 3
Morphine in spine vs. IV methadone for testicular cancer surgery pain
This trial compares two ways to manage pain after surgery for testicular cancer: a single injection of morphine into the spine (intrathecal morphine) vs. methadone given through an IV during surgery. The goal is to see which provides better pain relief and fewer side effects.
Indianapolis, IndianaAges 18–80 - NCT06133543Recruiting
Robotic sentinel node biopsy for testicular cancer
This trial uses a robot and a special dye (ICG) to find and remove the first lymph node that might contain cancer cells in men with testicular cancer. It aims to reduce unnecessary lymph node removal while still detecting spread.
DüsseldorfAges 18–99 - NCT06309745Recruiting
Lowering treatment for Stage II testicular cancer
This trial tests lowering the intensity of treatment (de-escalation) for Stage II seminoma, a type of testicular cancer. You may receive either a surgery to remove lymph nodes or a single round of chemotherapy (carboplatin), instead of more aggressive standard treatments, to see if it's safe and effective.
LondonAges 16 years+ - NCT07463508Recruiting
Bile acids as markers for testicular germ cell tumors
This study looks at whether levels of bile acids (substances made by your liver) can help doctors understand how testicular germ cell tumors grow and how they respond to treatment. It may help improve future care for people with this type of cancer.
Clermont-FerrandAges 18 years+ - NCT05264337Recruiting
Study for swelling after prostate or other urinary surgery
This study looks at swelling caused by lymph fluid buildup after urinary (urologic) surgery that removes lymph nodes. If you’re scheduled for or recently had this type of surgery, this trial may help researchers understand how to prevent or treat this swelling.
GothenburgAges 18 years+ - NCT04452305Recruiting
Frozen testicle tissue transplant to restore fertility
This study tests using previously frozen (cryopreserved) testicle cells or tissue to regrow testicular tissue. If you’ve had cancer treatment that can harm fertility, this may help restore natural fertility potential using your own tissue.
Pittsburgh, PennsylvaniaAges Any age - NCT06041503RecruitingPhase 2
Treating rare bladder and testicular cancers with targeted therapy
This trial tests a combination of two drugs (enfortumab vedotin and pembrolizumab) for people with certain rare cancers of the urinary tract or testicles. The goal is to see if these treatments can shrink tumors or stop them from growing.
Bethesda, MarylandAges 18–120 - NCT06587477Recruiting
Fertility in Men Who Had Cancer as Children
This study examines testicular function and semen quality in men who were treated for cancer before age 18 and are now in remission. It aims to understand how childhood cancer treatments affect long-term fertility.
Hong KongAges 18–50 - NCT04202094Enrolling by invitation
Fertility options for young men after childhood cancer treatment
This study looks at fertility outcomes in young men who had cancer or blood disorders as children and then received high-risk treatment that can affect future fertility. It also compares people who did or did not store testicular tissue through a biopsy when they were younger.
BrusselsAges 18 years+ - NCT02099734Recruiting
DNA registry for germ cell and testicular tumors
This study collects DNA and medical information to better understand germ cell and testicular tumors and possible inherited genetic causes. It may help researchers sort out how genetic changes relate to these cancers, even if you’re not receiving a new drug.
Basking Ridge, New JerseyAges 18 years+
Hear when a new Testicular Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for testicular cancer?
- Yes. Clin2 currently lists 50 recruiting testicular cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a testicular cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a testicular cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.