Clinical trials
Tobacco clinical trials
Below are recruiting tobacco clinical trials, each written for real people, not researchers. We’re tracking 176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07455526Recruiting
Help to quit smoking for veterans with mental illness
This program helps veterans who have a serious mental illness and use tobacco to get more support for quitting, such as connecting them with treatment options during their mental health visits.
Baltimore, MarylandAges Any age - NCT07812753Recruiting
Brain stimulation for smoking cessation
This study looks at how a non-invasive brain stimulation technique called TMS (which uses magnetic pulses to stimulate the brain) might affect the brain's reward system in people who smoke. The goal is to understand how to help people quit smoking more effectively.
Newark, New JerseyAges 18–60 - NCT07721883Recruiting
Social media and tobacco use in teens
This study looks at how social media affects teens' interest in tobacco products like e-cigarettes and vapes. Researchers want to talk with high school students to understand these influences and help prevent tobacco use.
Los Angeles, CaliforniaAges 14–17 - NCT07710820Recruiting
Can a heated tobacco product help you stop smoking?
This study tests whether having access to a heated tobacco product (a device that heats tobacco, not burns it) helps current cigarette smokers quit smoking. You'll try four different flavors over a week and then continue using one you like.
Brandon, FloridaAges 21–65 - NCT07688304Recruiting
Study on IQOS heated tobacco for adult smokers
This study looks at how adults who smoke cigarettes react to IQOS, a heated tobacco product. It aims to understand if it could be less addictive than smoking.
Columbus, OhioAges 21–65 - NCT06405074Recruiting
Ultrasound for Smoking Cessation in Veterans
This study tests if a gentle ultrasound aimed at a specific part of the brain (the insula) can help veterans who smoke tobacco reduce or quit smoking. The research is for veterans who smoke heavily and are motivated to think about quitting but are not currently in treatment.
Washington D.C., District of ColumbiaAges 18–75 - NCT05859451Recruiting
Heated tobacco product study for surgically treated leg fractures
This study looks at whether a tobacco heating system (instead of cigarettes) affects how well a surgically repaired tibia or femur fracture heals. It mainly targets smokers with a certain smoking history who do not want to join free smoking-cessation seminars.
Tübingen, Baden-WurttembergAges 18 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT07489443Recruiting
Helping pregnant women reduce tobacco and cannabis use
This study is testing a program to help pregnant women and new mothers cut back on or quit using tobacco and cannabis. It’s designed to see if the program is easy to use and helps improve health for both mom and baby.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07398443Recruiting
Study of marijuana and tobacco use in young adults
This study looks at how young adults use both marijuana and tobacco, and aims to understand their behaviors. It involves tasks and questionnaires, and may help develop better support for people who use both substances.
Providence, Rhode IslandAges 18–25 - NCT06170437Recruiting
Smoke-free Home Study in Subsidized Housing
This study looks at ways to help people who live in subsidized housing make their homes smoke-free. You may be able to join if you are a current smoker and smoke inside your home.
San Francisco, CaliforniaAges 18 years+ - NCT06913166Recruiting
Online Quiz on Smoking for Primary School Students
This trial tests if an online quiz game can teach kids about the harms of smoking and improve their attitudes and behaviors towards tobacco. It is for primary 5 and 6 students who can read Chinese and have a device at home.
Hong KongAges 9–13 - NCT07162935Recruiting
Cigarillo use study for young adults
This study looks at how young adults use cigarillos. You will smoke research cigarillos in a lab and answer questions. The goal is to understand cigarillo use to help with future regulation.
Oklahoma City, OklahomaAges 18–24 - NCT07132814Recruiting
Testing abuse potential of five oral nicotine products
This study tests how much people might want to use five different types of modern oral nicotine products (like pouches or lozenges) compared to smoking their usual cigarette. It helps researchers understand if these products could be less addictive than cigarettes.
Overland Park, KansasAges 21–60 - NCT07129590Recruiting
Trauma-informed care to help pregnant people quit smoking
This study tests whether a trauma-informed care approach can help pregnant people who have experienced trauma to quit smoking. The study involves clinicians and patients working together to improve smoking cessation support.
San Francisco, CaliforniaAges 18 years+ - NCT07107139Recruiting
Lab study on smokeless tobacco for daily smokers
This study tests how people who smoke daily react to a new type of smokeless tobacco product (like snus or dip) after trying it in a lab. You must have already taken part in our earlier auction study and be open to using a non-combusted tobacco product.
Buffalo, New YorkAges 21 years+ - NCT07049757Recruiting
Healthy Family Project: Reducing tobacco smoke in Chinese American homes
This study helps Chinese American families reduce tobacco use and secondhand smoke exposure. Smokers, family members, and community health workers are all welcome.
San Francisco, CaliforniaAges 18 years+ - NCT06986993RecruitingPhase 4
Semaglutide for smoking and weight in people with obesity
This study tests whether the medication semaglutide (similar to Ozempic/Wegovy) can help people who smoke and have obesity cut down on cigarettes, even if they aren't ready to quit. Participants will receive the drug and be monitored for changes in smoking habits and health.
Oklahoma City, OklahomaAges 18–65 - NCT06966362RecruitingPhase 4
Help cutting back on smoking for veterans not ready to quit
This study tests a medicine called varenicline (also known as Chantix) to help veterans who aren't ready to quit smoking yet but want to cut down. The goal is to see if it helps reduce how much they smoke.
San Diego, CaliforniaAges 21 years+ - NCT06945120Recruiting
Lung Health Program for Chinese and Korean Smokers
This study is testing a program to help Chinese and Korean adults who smoke to improve their lung health. You may be able to join if you are a current smoker, speak Korean, Mandarin, or English, and live in the U.S.
Boston, MassachusettsAges 18–100 - NCT05786547RecruitingPhase 3
Varenicline plus support to help quit tobacco in HIV care
This Phase 3 trial tests a quit-smoking program using varenicline (a medicine) plus additional support, for people with HIV who currently use tobacco. It may help you stop smoking or using tobacco and stay quit with safer, guided care.
Aurora, ColoradoAges 18 years+ - NCT06873009Enrolling by invitation
Can therapy help men in prison quit smoking?
This trial tests if cognitive behavioural therapy (a type of talk therapy that changes thinking and habits) can help men in prison stop smoking. It aims to see what works best and for whom.
Paris, Île-de-France RegionAges 18 years+ - NCT06851936Recruiting
Help quitting tobacco for cancer survivors and their caregivers
This study tests a program to help people with a history of cancer and their family caregivers quit using tobacco or nicotine products. You may help researchers learn what works best for supporting quitting in this group.
Gainesville, FloridaAges 18 years+ - NCT06798324RecruitingPhase 4
Brain stimulation plus smoking cessation medication for quitting smoking
This trial tests whether combining brain stimulation (tDCS) with a smoking cessation medication (varenicline) helps people quit smoking. You would attend daily visits for two weeks.
Toronto, OntarioAges 18–85
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Common questions
- Are there clinical trials for tobacco?
- Yes. Clin2 currently lists 176 recruiting tobacco studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tobacco trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tobacco trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.