Clinical trials
Tonsillectomy clinical trials
Below are recruiting tonsillectomy clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04767048RecruitingPhase 2
Robot or laser tongue scraping plus tonsil removal to assess lymph nodes
This trial looks at whether a more precise procedure—removing a small area of tongue lining using a robot or laser, along with tonsil removal—can find the likely source of stubborn swollen neck lymph nodes. It’s designed for people with signs of head-and-neck cancer in lymph nodes, but no clear primary tumor found yet.
CaenAges 18 years+ - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT03420638RecruitingPhase 4
Pain relief after tonsillectomy
This study tests a long-lasting numbing medicine (bupivacaine) injected during tonsillectomy to see if it helps reduce pain after surgery. It may offer better pain control than standard care.
Ann Arbor, MichiganAges 18 years+ - NCT07780760Recruiting
Numbing throat spray to ease pain after tonsil removal in children
This study tests whether a numbing mist sprayed into the throat before surgery can reduce sore throat pain children feel after having their tonsils removed. It compares two numbing medicines to see if one works better than the other.
Al FayyumAges 3–15 - NCT07724938Recruiting
Combination tonsil removal and nerve implant for sleep apnea
This study tests if removing the tonsils together with implanting a nerve stimulator (Hypoglossal Nerve Stimulation) can better treat sleep apnea in people whose throat sides collapse during sleep.
Boston, MassachusettsAges 18 years+ - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07489742Recruiting
Ondansetron lozenge vs IV for shivering prevention in tonsillectomy
This trial tests whether an ondansetron lozenge works as well as IV ondansetron to prevent shivering after tonsillectomy in children. It could offer a needle-free way to reduce side effects during recovery.
Tanta, El-GharbiaAges 4–15 - NCT07375342Recruiting
Melatonin for calming children after tonsil removal
This trial tests whether giving melatonin before surgery can help children be less agitated and confused when waking up from anesthesia after tonsil removal. If it works, it could make the recovery smoother for both children and parents.
BanhāAges 4–10 - NCT07118579RecruitingPhase 4
Comparing two anesthesia drugs for kids' tonsil surgery
This study compares two newer sedation drugs (remimazolam and ciprofol) to see which one better prevents breathing or airway problems during and after tonsil surgery in children.
Wuhan, HubeiAges 2–12 - NCT07074951Recruiting
Tonsillectomy and immune therapy for high-risk IgA kidney disease
This trial tests whether removing the tonsils (tonsillectomy) plus immune-suppressing therapy can help people with a high-risk form of IgA nephropathy, a kidney disease. It aims to slow down kidney damage and delay the need for dialysis.
Saint PetersburgAges 18–75 - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT07635719Recruiting
Comparing surgical tools for tonsil and adenoid removal
This study compares different surgical tools used during tonsil and adenoid removal surgery in children. The goal is to see which tool works best and is safest for this common pediatric surgery.
The Bronx, New YorkAges 1–18 - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
San Francisco, CaliforniaAges 3–17 - NCT07574476Enrolling by invitation
Fasting Time and Pain After Tonsil Surgery
This study looks at whether the length of time patients fast (don't eat or drink) before tonsil removal surgery affects how much pain they experience afterward. Researchers hope to find the best fasting approach to reduce post-surgery discomfort.
Columbus, OhioAges Up to 18 years - NCT07494370Recruiting
Adenoid surgery study in children
This study looks at children getting adenoid surgery (adenoidectomy) to see how different factors and surgical methods affect whether any adenoid tissue is left behind. It aims to help improve surgical outcomes.
Pavia, LombardyAges birth–18 years - NCT06767696Recruiting
Neck position and breathing tube pressure in children
This study checks if tilting a child's head back during surgery changes the pressure in the breathing tube. It helps doctors make sure children's airways stay safe during tonsil or adenoid removal.
Ankara, KeçiörenAges 2–18 - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT07188779RecruitingPhase 2
Impact of a special gel on tonsillectomy recovery in children
This trial tests whether applying a special gel called RADA16 to the surgical site after tonsillectomy (removal of tonsils) can help children heal better and with less pain. It may offer a new way to improve recovery after this common surgery.
Livingston, New JerseyAges 3–17 - NCT07176533Recruiting
Nerve block for pain after tonsil surgery in kids
This study tests a nerve block (a numbing injection near the cheekbone) to reduce pain after tonsil surgery in children with sleep apnea. It might help them have less pain and recover more comfortably.
London, OntarioAges 3–9 - NCT07060495RecruitingPhase 3
RADA16 gel for pain after adult tonsillectomy
This trial tests a new gel (RADA16) placed on the tonsil area after surgery to see if it helps reduce pain and speed healing. It is for adults having a standard tonsillectomy.
Livingston, New JerseyAges 18 years+ - NCT06580509RecruitingEarly Phase 1
Spray medicine for bleeding after tonsil removal in children
This study tests if a sprayed form of the medicine tranexamic acid (which helps blood clot) can stop bleeding after tonsillectomy in children. It is for children ages 2 to 17 who come to the emergency room with bleeding that starts more than a day after surgery.
San Antonio, TexasAges 2–17 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17
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Common questions
- Are there clinical trials for tonsillectomy?
- Yes. Clin2 currently lists 26 recruiting tonsillectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tonsillectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tonsillectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.