Clinical trials
Tonsillectomy clinical trials
Below are recruiting tonsillectomy clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04767048RecruitingPhase 2
Robot or laser tongue scraping plus tonsil removal to assess lymph nodes
This trial looks at whether a more precise procedure—removing a small area of tongue lining using a robot or laser, along with tonsil removal—can find the likely source of stubborn swollen neck lymph nodes. It’s designed for people with signs of head-and-neck cancer in lymph nodes, but no clear primary tumor found yet.
CaenAges 18 years+ - NCT04853173Recruiting
Testing pain-relief methods for adult tonsillectomy
This trial looks at how best to control pain for adults having tonsil removal (tonsillectomy) on an outpatient basis. It may help find a pain plan that works well and is safe for people like you.
BesançonAges 18 years+ - NCT07489742Recruiting
Ondansetron lozenge vs IV for shivering prevention in tonsillectomy
This trial tests whether an ondansetron lozenge works as well as IV ondansetron to prevent shivering after tonsillectomy in children. It could offer a needle-free way to reduce side effects during recovery.
Tanta, El-GharbiaAges 4–15 - NCT07370129Enrolling by invitation
Numbing injection for pain after tonsil surgery
This study tests a numbing injection near a nerve in your nose to see if it can reduce pain and help you recover faster after tonsillectomy. It is a non-drug approach that may offer an alternative to strong pain medicines.
Ankara, AnkaraAges 12 years+ - NCT07118579RecruitingPhase 4
Comparing two anesthesia drugs for kids' tonsil surgery
This study compares two newer sedation drugs (remimazolam and ciprofol) to see which one better prevents breathing or airway problems during and after tonsil surgery in children.
Wuhan, HubeiAges 2–12 - NCT06606262Recruiting
Tonsil removal surgery: total vs partial for recurrent tonsillitis
This study compares two different surgeries for treating frequent tonsillitis (sore throats that come back often): removing the entire tonsils versus removing only part of them. It aims to see which approach works better and has fewer side effects.
AalborgAges 15 years+ - NCT07375342Recruiting
Melatonin for calming children after tonsil removal
This trial tests whether giving melatonin before surgery can help children be less agitated and confused when waking up from anesthesia after tonsil removal. If it works, it could make the recovery smoother for both children and parents.
BanhāAges 4–10 - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT07074951Recruiting
Tonsillectomy and immune therapy for high-risk IgA kidney disease
This trial tests whether removing the tonsils (tonsillectomy) plus immune-suppressing therapy can help people with a high-risk form of IgA nephropathy, a kidney disease. It aims to slow down kidney damage and delay the need for dialysis.
Saint PetersburgAges 18–75 - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT05460689Recruiting
Phone app support for families before pediatric ear-nose-throat surgery
This trial tests whether a mobile phone app can better support caregivers of children going into tonsil and/or adenoid surgery (sometimes with ear tube placement) around the time of the operation. It may help families feel more informed and prepared before and after surgery.
TriesteAges 2–10 - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT06580509RecruitingEarly Phase 1
Spray medicine for bleeding after tonsil removal in children
This study tests if a sprayed form of the medicine tranexamic acid (which helps blood clot) can stop bleeding after tonsillectomy in children. It is for children ages 2 to 17 who come to the emergency room with bleeding that starts more than a day after surgery.
San Antonio, TexasAges 2–17 - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT06767696Recruiting
Neck position and breathing tube pressure in children
This study checks if tilting a child's head back during surgery changes the pressure in the breathing tube. It helps doctors make sure children's airways stay safe during tonsil or adenoid removal.
Ankara, KeçiörenAges 2–18 - NCT07635719Recruiting
Comparing surgical tools for tonsil and adenoid removal
This study compares different surgical tools used during tonsil and adenoid removal surgery in children. The goal is to see which tool works best and is safest for this common pediatric surgery.
The Bronx, New YorkAges 1–18 - NCT07494370Recruiting
Adenoid surgery study in children
This study looks at children getting adenoid surgery (adenoidectomy) to see how different factors and surgical methods affect whether any adenoid tissue is left behind. It aims to help improve surgical outcomes.
Pavia, LombardyAges birth–18 years - NCT06543823Recruiting
New bandage for throat surgery pain relief
This trial tests a special wound dressing (SUPRATHEL 250) placed inside the throat after tonsil removal. It aims to see if it helps throat wounds heal faster with less pain.
Stuttgart, Baden-WurttembergAges 18 years+ - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT07188779RecruitingPhase 2
Impact of a special gel on tonsillectomy recovery in children
This trial tests whether applying a special gel called RADA16 to the surgical site after tonsillectomy (removal of tonsils) can help children heal better and with less pain. It may offer a new way to improve recovery after this common surgery.
Livingston, New JerseyAges 3–17 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT06579937RecruitingPhase 4
Esketamine for behavior after tonsil surgery in children
This study tests whether a medicine called esketamine can help reduce negative behavior changes in children after tonsillectomy or adenoidectomy surgery. Esketamine is given during anesthesia to see if it helps children recover with fewer emotional or behavioral issues.
Fuzhou, FujianAges 3–7
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Common questions
- Are there clinical trials for tonsillectomy?
- Yes. Clin2 currently lists 27 recruiting tonsillectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tonsillectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tonsillectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.