Clinical trials
Trauma clinical trials
Below are recruiting trauma clinical trials, each written for real people, not researchers. We’re tracking 379 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06070350RecruitingPhase 3
Massive transfusion for life-threatening bleeding in children
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Tucson, ArizonaAges Up to 17 years - NCT06069154Enrolling by invitation
Freezing nerves for rib fracture pain
This study tests a procedure called cryoneurolysis, which uses cold to temporarily freeze nerves near broken ribs to relieve pain. It is for adults who have 1 to 6 recently broken ribs with at least moderate pain and are already getting a nerve block injection.
La Jolla, CaliforniaAges 18 years+ - NCT06046859RecruitingPhase 4
Can fluoxetine help recovery after serious injuries?
This study tests whether giving the antidepressant fluoxetine (Prozac) right after a traumatic injury can help improve mental and physical recovery. It is for people who have broken bones or internal injuries from an accident and may be feeling down.
Gainesville, FloridaAges 18–85 - NCT06049784Recruiting
Visual biofeedback before labor using a self-operated ultrasound device
This trial tests whether using a self-operated ultrasound device to provide visual biofeedback before labor can help with the birthing process. It is for low-risk pregnancies planning a vaginal delivery.
Petah TikvaAges 18 years+ - NCT06033027Recruiting
Testing a soft robotic glove for hand help
This trial tests a soft robotic glove that helps you grip and hold objects if your hand is weak due to a nerve problem or injury. It's meant for people who have trouble with daily tasks like eating or dressing.
Enschede, OverijsselAges 18–90 - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT06015451Recruiting
Exercise for concussion symptoms and headache
This trial tests whether a carefully supervised exercise program can help people who still have headaches or other symptoms weeks after a mild head injury. If you get symptoms when you try to be active, this study may offer a structured way to help you recover.
TrondheimAges 18–65 - NCT05987735Enrolling by invitation
Blame-Less program for trauma-related shame and guilt
This study tests a 7-week psychoeducation program called BLAME-LESS to help people who feel guilt or shame after a traumatic event. It aims to reduce these feelings by providing clear information on trauma responses.
Almelo, OverijsselAges 12–18 - NCT05976347RecruitingPhase 4
Treatment for depression after certain bone fractures
This trial tries to find and treat depression in people who have recently had surgery for an arm, leg, or pelvis fracture. It may help by screening for depression soon after surgery and offering a new depression treatment approach if you qualify.
Winston-Salem, North CarolinaAges 18 years+ - NCT05964140RecruitingPhase 3
Testing antibiotics after jaw fracture surgery
This trial studies whether giving (or how giving) antibiotics affects outcomes after surgery for a broken lower jaw (mandible). It may help reduce infection risk and antibiotic-related side effects if the right approach is chosen for the right patients.
Blackburn, LancashireAges 18 years+ - NCT05972265Recruiting
Exercise for memory and thinking after childhood trauma
This study tests if exercise can help improve memory, attention, and thinking in adults aged 40–60 who experienced child abuse or neglect and have concerns about their cognitive function. You'll need to be a native English speaker, generally healthy, and not currently very active.
Austin, TexasAges 40–60 - NCT05958342RecruitingPhase 2
Calcium and vasopressin for bleeding shock after major injury
This trial tests whether giving calcium and vasopressin early can improve outcomes in people with major injury who are at risk for life-threatening bleeding shock. It mainly includes patients who need rapid blood transfusion and likely major surgery to stop bleeding.
Chandler, ArizonaAges 18–90 - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05856370Recruiting
Study for follow-up of Medtronic spine or skull devices
This study checks how well certain Medtronic devices for the skull or spine are working in real-world care. If you’re getting one of these devices, you may be asked to do scheduled follow-up visits and assessments to confirm safety and performance.
Tucson, ArizonaAges 18 years+ - NCT05816083Recruiting
Virtual reality tool for teens and young adults after trauma
This study tests a virtual reality program to help young people who have been through serious violence or sexual assault (“ITE”). It’s also open to certain healthcare workers who support these young people.
Charleston, South CarolinaAges 15–30 - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65 - NCT05700201Recruiting
Study of heart health in adults with trauma symptoms
This study looks at how trauma-related symptoms (like PTSD symptoms) may affect heart health. You may be asked to do light activity—so your study team can see how your body responds.
Fort Lauderdale, FloridaAges 18 years+ - NCT05699174RecruitingPhase 3
Compare two antibiotic routes for infected broken bones after surgery
This Phase 3 trial tests whether giving antibiotics by mouth (PO) works as well as giving antibiotics through a vein (IV) for an infected fracture that has not healed after prior surgery. It may help you understand which approach is safer and more effective for getting the bone to heal.
Indianapolis, IndianaAges 18 years+ - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05558527Recruiting
Study of how relationships affect noticing threat cues
This study looks at how being in a stable romantic relationship changes how you notice and react to threat-related cues. It may help researchers understand factors that shape fear and alertness, which could guide future mental health treatments.
Reno, NevadaAges 18–65 - NCT04713722Recruiting
Study of early stress and depression using brain imaging
This study looks at how early life stress may be linked to depression, using brain scans. You’ll be asked about your history and asked to do brain imaging to help researchers understand these brain and mood changes.
Belmont, MassachusettsAges 20–32 - NCT05500066Enrolling by invitation
Shoulder implant study for people needing shoulder replacement
This trial studies a specific shoulder replacement implant system. It may help people with damaged shoulder joints by testing how well the implant works and how it affects recovery and function.
Denver, ColoradoAges 18 years+ - NCT05497115Recruiting
Care model to improve access to mental health after trauma
This trial tests a practical care plan to help people get mental health support after a traumatic injury, especially if screening suggests risk for PTSD or depression. It may help you connect faster to the right kind of treatment after your injury.
Washington, VirginiaAges 16 years+
Hear when a new Trauma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for trauma?
- Yes. Clin2 currently lists 379 recruiting trauma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a trauma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a trauma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.