Clinical trials
Trauma clinical trials
Below are recruiting trauma clinical trials, each written for real people, not researchers. We’re tracking 379 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06451523Recruiting
Alliance180 Program for well-being in veterans and first responders
This study looks at how the Alliance180 Program helps improve well-being in adults who have been exposed to trauma. It is for veterans, first responders, or frontline healthcare workers who are currently experiencing trauma-related symptoms.
Saratoga Springs, New YorkAges 18–99 - NCT06426303RecruitingPhase 4
Alcohol Use Disorder Treatment in Veterans: Brain and Inflammation
This study is for veterans with alcohol use disorder who have been sober for 5 days to 3 weeks. It looks at how trauma, inflammation, and brain function relate to alcohol problems and how well treatment works. You will be in a group that gets medication or a placebo.
Portland, OregonAges 18–60 - NCT04137237Recruiting
Study of carbon hand and wrist implants after surgery
This trial follows people who receive a special hand or wrist implant made of pyrocarbon (a strong, durable material). It aims to measure outcomes over time to see how well the implant works and how patients do functionally.
LyonAges 18 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06367556Recruiting
Emotion and stress support for caregivers of children with cancer
This trial offers a program called EASE (Emotion and Symptom-Focused Engagement) to help family caregivers of children with cancer manage their emotions and stress. It aims to see if providing support to caregivers improves their well-being.
Toronto, OntarioAges 18 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06340633RecruitingPhase 2
Testing SPI-1005 with cochlear implant surgery
This trial tests an oral medication, SPI-1005, given to adults receiving a cochlear implant to see if it improves hearing outcomes. It may help people with moderate to profound hearing loss who are scheduled for implant surgery.
Iowa City, IowaAges 18 years+ - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Scottsdale, ArizonaAges 18 years+ - NCT06330467Recruiting
Study of dissociative identity disorder in adults with childhood trauma
This study looks at how common dissociative identity disorder (a condition where a person may have two or more distinct identities) is in adults who experienced trauma as children. Participants will undergo a psychological evaluation to help researchers understand the link between childhood trauma and dissociative symptoms.
NancyAges 18 years+ - NCT06337292RecruitingPhase 3
Wound vacuum therapy for high-risk leg fractures
This trial tests if a special wound vacuum (negative pressure therapy) applied after surgery can lower the risk of infections and other complications in people with severe leg fractures. If you have a high-risk tibia or ankle fracture, this treatment may help you heal better.
Baltimore, MarylandAges 18 years+ - NCT06332209Recruiting
Telehealth vs. in-person therapy for trauma in Puerto Rican youth
This trial compares two ways of giving a type of therapy called Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) to children and teens in Puerto Rico who have been through a traumatic event and have post-traumatic stress symptoms. One group receives therapy in person at a clinic, and the other group receives therapy through video calls (telehealth), to see which works better.
Charleston, South CarolinaAges 7–18 - NCT06278922Recruiting
A therapy toolkit for Deaf people with alcohol and trauma issues
This study tests a therapy toolkit designed for Deaf or hard-of-hearing people who struggle with alcohol use and have experienced trauma. The therapy is provided in ASL via video sessions, and the goal is to see if it helps reduce drinking and PTSD symptoms.
Worcester, MassachusettsAges 18 years+ - NCT06293469Recruiting
Speeding up flap surgery for severe leg injuries
This trial tests whether performing flap surgery sooner after a severe leg injury below the knee leads to better outcomes. If you have an open fracture or dislocation that needs a flap, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT06285708Recruiting
Making PTSD therapy safer for people with suicidal thoughts
This study tests whether a type of therapy called Prolonged Exposure can be more effective and safe for people who have both PTSD and suicidal thoughts. The goal is to help reduce trauma symptoms while addressing suicide risk.
Columbus, OhioAges 18 years+ - NCT06262178Recruiting
Parenting support for mothers in military families
This study tests a parenting program designed to help mothers in military families cope with past trauma and improve their relationship with their child. The program aims to reduce PTSD and depression symptoms while increasing parenting confidence.
El Paso, TexasAges 18 years+ - NCT06220448Recruiting
Blunt adrenal injury study for trauma patients
This study looks at how adrenal gland injuries from blunt force trauma (like a car crash or fall) affect people. You may qualify if you had a blunt injury to your chest or belly area.
Miano, LombardyAges 16–99 - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06216600Recruiting
Women's strength and resilience program for HIV and substance use
This study tests a program for women living with HIV who also struggle with substance use or heavy drinking. It combines exercise and support to help build strength and resilience. You may qualify if you've missed some HIV medications, have a detectable viral load, and have experienced violence.
San Diego, CaliforniaAges 18 years+ - NCT06201676RecruitingPhase 4
Low-dose short-term ketorolac to cut opioid use after bone surgery
This study tests whether giving a low dose of a non-steroidal anti-inflammatory drug (NSAID) called ketorolac for a short time after orthopedic surgery can reduce the need for strong painkillers like opioids. It is for people who have broken bones that need surgery with metal plates, screws, or rods.
Boston, MassachusettsAges 18–70 - NCT06142435Recruiting
Eye scan to detect and monitor mild brain injury
This study uses a retinal scanner to see if it can detect and track brain injury after a mild head trauma (concussion). If you are between 18 and 45 years old and had a head injury within the past two weeks, this test might help doctors learn more about your injury without invasive procedures.
Boston, MassachusettsAges 18–45 - NCT04839497RecruitingPhase 2
Safety and benefit of injecting fibroblast cells in leg amputees’ skin
This Phase 2 study tests whether injecting a patient’s own (autologous) fibroblast cells into the end of a transtibial (below-knee) amputation is safe and may improve outcomes. You may qualify if you have a certain type of prosthesis timing and healthy skin on the stump, and you can follow frequent visit and wound-care instructions.
Baltimore, MarylandAges 18–75 - NCT06113211RecruitingPhase 4
Non-opioid pain control after fracture surgery
This trial tests a combination of non-opioid medications to manage pain after surgery for a broken bone, aiming to reduce or avoid the use of opioids. It may help you control pain without the risks of strong painkillers.
Detroit, MichiganAges 18–80 - NCT04585685Recruiting
Healthy recovery program for PTSD after sexual trauma
This study looks at how to help people recover from PTSD symptoms after sexual trauma, including feeling mentally “contaminated.” You may be eligible if you currently meet criteria for PTSD and report these contamination feelings, and you can avoid starting other trauma treatments during the study.
Lexington, KentuckyAges 18 years+ - NCT02880163Recruiting
Test foam used to stop dangerous internal abdominal bleeding
This trial tests whether an expandable foam can quickly help slow or control life-threatening bleeding inside the belly. It is designed for emergency situations where surgery to stop the bleeding will happen soon.
Birmingham, AlabamaAges 15 years+
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Common questions
- Are there clinical trials for trauma?
- Yes. Clin2 currently lists 379 recruiting trauma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a trauma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a trauma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.