Clinical trials
Type 1 diabetes clinical trials
An autoimmune condition where the body makes little or no insulin. We’re tracking 874 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03528226Recruiting
Exercise program to improve blood vessel function in type 1 diabetes
This trial studies whether an exercise training program can improve how well your blood vessels work in people with type 1 diabetes. It may help assess benefits beyond blood sugar control.
LilleAges 18–50 - NCT03710928Recruiting
Very low carbohydrate diet versus standard diet for type 1 diabetes
This study compares a very low carbohydrate diet to a regular diet to see how well blood sugar control works for adults with type 1 diabetes. It may help you understand which eating pattern is easier and safer for managing daily glucose with modern diabetes technology.
Boston, MassachusettsAges 18–40 - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Tucson, ArizonaAges 18 years+ - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT05145374Recruiting
Testing an insulin pump system for exercise and stress swings
This study tests a smarter (automated) insulin pump approach to help prevent blood sugar problems when you do physical activity or when you’re under sudden stress. It may help people with type 1 diabetes use insulin more safely during real-life changes.
Chicago, IllinoisAges 20–60 - NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05767450Recruiting
Test for early type 1 diabetes in children
This study looks at children who have just started insulin for new-onset type 1 diabetes. It aims to test an intervention early in the course of the disease, which may help change how the immune system and diabetes progress.
Milan, MilanAges 7–17 - NCT05790785Recruiting
Tests blood vessel changes in kids soon after type 1 diabetes
This study looks at how blood vessels and blood pressure change in children soon after being diagnosed with type 1 diabetes. It may help doctors better understand early vascular risk and how to monitor it.
Vancouver, British ColumbiaAges 8–18 - NCT05899439Recruiting
Blood test study of immune changes in type 1 diabetes
This study looks at how your immune system changes over time and how that relates to developing type 1 diabetes. You may be able to join if you can have blood drawn, since the study focuses on blood samples.
Gainesville, FloridaAges birth–100 years - NCT05973799Recruiting
Fasting test in people with type 1 diabetes
This study looks at how your body responds to low blood sugar during a controlled period of fasting. It may help doctors understand the natural defenses your body uses to prevent dangerous lows in type 1 diabetes.
Cincinnati, OhioAges 18–45 - NCT06171412Recruiting
Peer mentoring to help Black and Latinx people with type 1 diabetes use CGM more
This study tests whether support from a peer mentor can help Black and Latinx adults with type 1 diabetes who currently use a continuous glucose monitor (CGM) less than half the time to use it more regularly. You'll join remote video sessions with a mentor who has experience with diabetes.
New Haven, ConnecticutAges 13–21 - NCT06272136Recruiting
Non-invasive continuous glucose monitor study for diabetes
This trial tests a new non-invasive continuous glucose monitor that you wear on your wrist like a watch, without needing finger sticks. It is designed for people with type 1 or type 2 diabetes who use insulin or certain diabetes pills.
Neuss, Nordrhein-WestfallenAges 18–65 - NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65 - NCT06338553RecruitingEarly Phase 1
GLP-1 drug for early type 1 diabetes
This study tests whether a GLP-1 receptor agonist (a type of medicine that helps control blood sugar and appetite) can improve metabolic health in people with early type 1 diabetes. It may be an option if you have already taken teplizumab to delay the disease or were recently diagnosed with type 1 diabetes.
Nashville, TennesseeAges 12–50 - NCT06363916Recruiting
Testing a new automated insulin delivery system for type 1 diabetes
This study tests a new hybrid closed-loop system (an automated insulin pump) in people with type 1 diabetes whose blood sugar is not well controlled. It aims to see if the system is safe and helps improve glucose levels.
AngersAges 7–75 - NCT06445361Recruiting
Liver fat study in type 1 diabetes
This trial looks at how common fatty liver disease is in people with type 1 diabetes. Doctors will check your liver with tests to learn more and find out if you might be at risk.
Genk, LimburgAges 18 years+ - NCT06455319RecruitingPhase 2
Personalized ATG with or without verapamil for new type 1 diabetes
This trial tests a new way to give a medicine called anti-thymocyte globulin (ATG) with or without verapamil, a blood pressure drug. It aims to slow down the loss of insulin-making cells in people newly diagnosed with type 1 diabetes.
Aurora, ColoradoAges 6–35 - NCT06458088Recruiting
Sugar-related substances and blood vessel problems in type 1 diabetes
This study looks at how certain sugar-related substances in the blood (called advanced glycation products) are linked to blood vessel problems in people with type 1 diabetes. It follows up with participants from an earlier study at Reims Hospital.
ReimsAges 18 years+ - NCT06470295RecruitingEarly Phase 1
C-peptide's effect on low blood sugar response
This study tests whether C-peptide (a substance made by the pancreas) can help your body respond better to low blood sugar (hypoglycemia). It's a very early trial for people without certain health conditions.
Cincinnati, OhioAges 18–40 - NCT06474598RecruitingPhase 2
Test of MTX228 for type 1 diabetes with some insulin
This study tests a new medication, MTX228, to see if it can help people with type 1 diabetes who still make some insulin. It may slow the loss of your own insulin production and improve blood sugar control.
Edmonton, AlbertaAges 18–65 - NCT06496412Recruiting
Fecal transplant for brain health in type 1 diabetes
This trial tests whether transplanting healthy bacteria into your gut can improve memory and thinking skills in people with long-term type 1 diabetes. If you have had type 1 diabetes for 10 years or more, this study may help find a new way to protect your brain.
Changsha, HunanAges 18–60 - NCT06575790Recruiting
Comparing simplified meal boluses to carb counting for teens with automated insulin pumps
This study tests if a simpler way of calculating meal insulin works as well as counting carbohydrates for teens using hybrid closed loop (automated insulin) systems. If you're a teen with type 1 diabetes and use an automated pump, this trial could help find an easier mealtime routine.
Aurora, ColoradoAges 14–26 - NCT07592000RecruitingPhase 1/Phase 2
New Treatment for Type 1 Diabetes With Kidney Disease
This study tests a new experimental medication for people with type 1 diabetes who experience dangerous low blood sugar episodes and have early-stage kidney disease. The trial aims to help improve blood sugar control and reduce these risky episodes.
Chicago, IllinoisAges 18–70
Hear when a new Type 1 diabetes trial opens
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Common questions
- Are there clinical trials for type 1 diabetes?
- Yes. Clin2 currently lists 874 recruiting type 1 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 1 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.