Clinical trials
Type 1 diabetes clinical trials
An autoimmune condition where the body makes little or no insulin. We’re tracking 862 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06324604RecruitingPhase 1
Safety study of MTX-101 in healthy adults
This trial tests a new drug called MTX-101 in healthy volunteers to see if it is safe and how the body processes it. It helps determine the right dose before testing in patients with certain conditions.
Heidelberg, VictoriaAges 18–65 - NCT03228732RecruitingEarly Phase 1
Fluoxetine and/or DHEA in people with type 1 diabetes
This early-stage study tests whether the medicines fluoxetine and/or DHEA can improve health in adults with type 1 diabetes. It’s mainly looking for people without major diabetes complications or major medical problems to safely study the effects.
Baltimore, MarylandAges 18–50 - NCT05899439Recruiting
Blood test study of immune changes in type 1 diabetes
This study looks at how your immune system changes over time and how that relates to developing type 1 diabetes. You may be able to join if you can have blood drawn, since the study focuses on blood samples.
Gainesville, FloridaAges birth–100 years - NCT05823142Recruiting
Sleep-focused coaching for adults with type 1 diabetes
This trial tests a health behavior program designed to improve sleep health in adults living with type 1 diabetes. It may help you if your sleep patterns are affecting your health and you meet their specific diabetes control and eligibility rules.
Atlanta, GeorgiaAges 18–40 - NCT05756829Recruiting
Virtual education program for adults with type 1 diabetes
This study tests a 6-month online education and support program to help adults manage type 1 diabetes using insulin pump therapy or multiple daily insulin shots. It may help you improve understanding, day-to-day decision-making, and diabetes self-care with ongoing check-ins.
Kitchener, OntarioAges 18 years+ - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05498116RecruitingPhase 4
Montelukast to improve kidney and blood vessel function in type 1 diabetes
This trial tests whether montelukast, a medicine commonly used for allergies, can improve kidney health and blood vessel function in adults with long-term type 1 diabetes. You may join a treatment group and have kidney and circulation measurements taken over the study period.
Aurora, ColoradoAges 18–80 - NCT05258292Recruiting
Track blood sugar changes with your period in type 1 diabetes
This study monitors how your blood sugar (glucose) changes across your menstrual cycle using a continuous glucose monitor. It may help researchers understand patterns that could improve diabetes care around monthly hormonal changes.
Montreal, QuebecAges 18–50 - NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT05054361Recruiting
Study gut immunity changes in children with type 1 diabetes
This study looks at how a type of immune cell (MAIT cells) and the gut (microbiota and gut lining) change around the time type 1 diabetes starts in children. It may help researchers understand why type 1 diabetes begins and how the gut and immune system are connected.
AntonyAges 1–15 - NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Tucson, ArizonaAges 18 years+ - NCT03528226Recruiting
Exercise program to improve blood vessel function in type 1 diabetes
This trial studies whether an exercise training program can improve how well your blood vessels work in people with type 1 diabetes. It may help assess benefits beyond blood sugar control.
LilleAges 18–50 - NCT01999361Recruiting
Prevent new immune reaction after islet transplant failure
This study looks at ways to prevent the body from developing a new harmful immune reaction after an islet transplant no longer works. It may help people who have already lost a transplanted islet graft from getting harder-to-treat immune responses later.
Miami, FloridaAges 18–70 - NCT01999374Recruiting
Long-term follow-up for people with transplanted islet cells
This study checks how well transplanted islet cells are working over time and monitors long-term safety. If you previously received an islet transplant and are still using medicine to prevent rejection, you may be followed again.
Miami, FloridaAges 18–65 - NCT02000687Recruiting
Long-term follow-up after islet transplant graft failure
This study follows people over the long term after their islet transplant fully stops working. It aims to learn what happens after complete graft loss and monitor health outcomes over time.
Miami, FloridaAges 18–75 - NCT07835360Recruiting
Body changes after starting GLP-1 medications for weight or diabetes
This study looks at how your body composition (muscle and fat) changes after you start a GLP-1 medication for obesity or type 2 diabetes. You will be followed for a year with body scans to see the effects.
Mexico City, Mexico CityAges 18 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07574333Recruiting
Breathing Training to Help Type 2 Diabetes Management
This study tests whether special breathing exercises that alternate between low and high oxygen levels can help people with type 2 diabetes manage their condition better. Researchers want to see if short or longer courses of this training improve blood sugar control and overall health.
MoscowAges 50–74 - NCT01984762Recruiting
Weight-loss surgery for type 2 diabetes
This study tests whether two weight-loss operations (sleeve gastrectomy or Roux-en-Y gastric bypass) can improve type 2 diabetes. It may help people with higher body weight and diabetes control, but it also requires meeting safety and health criteria.
GothenburgAges 18–60 - NCT03987308Recruiting
Test shot medicine versus insulin pump for new type 2 diabetes
This study compares a continuous “under the skin” diabetes medicine (called beinaglutide) with an insulin pump (CSII) in people who were recently diagnosed with type 2 diabetes. It aims to see which approach works better and is safer for controlling blood sugar.
Beijing, Beijing MunicipalityAges 18–70 - NCT07120334Recruiting
Mobile health app for stroke survivors with prediabetes or diabetes
This trial tests a mobile app that helps people recovering from a stroke who also have prediabetes or type 2 diabetes improve their diet and health. You will use the app for about 12 weeks, and it may help you manage your blood sugar and prevent future strokes.
Honolulu, HawaiiAges 30–65 - NCT05593549RecruitingEarly Phase 1
Studying blood vessel damage in type 2 diabetes
This early study looks at how “autophagy” (your body’s cell recycling process) relates to small blood-vessel problems in people with type 2 diabetes. It may help researchers understand mechanisms and possible future treatments, mainly for people who meet specific health and medication criteria.
Milwaukee, WisconsinAges 18–80 - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70
Hear when a new Type 1 diabetes trial opens
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Common questions
- Are there clinical trials for type 1 diabetes?
- Yes. Clin2 currently lists 862 recruiting type 1 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 1 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.