Clinical trials
Ulcerative Colitis clinical trials
Below are recruiting ulcerative colitis clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07752446Recruiting
Mediterranean diet and time-restricted eating for ulcerative colitis
This study tests whether following a Mediterranean diet and limiting eating to a certain time window each day can help maintain remission in people with ulcerative colitis. It aims to see if this lifestyle change can keep the condition from flaring up.
Santiago, Santiago MetropolitanAges 18–60 - NCT05786404RecruitingPhase 1
Fecal transplant study for people with active ulcerative colitis
This trial tests whether transplanting stool bacteria (called fecal microbiota transplantation, or FMT) can improve symptoms in people with active ulcerative colitis. You may be able to help test a new approach for restoring gut bacteria, while receiving standard ulcerative colitis care from your doctor.
Houston, TexasAges 18 years+ - NCT06979336RecruitingPhase 2
New drug for moderate to severe UC
This study tests an experimental drug called RO7837195 for people with moderate to severe ulcerative colitis (UC) who haven't gotten enough help from other treatments. It aims to see if this new drug can reduce inflammation and improve symptoms.
Lancaster, CaliforniaAges 18 years+ - NCT04908644Recruiting
Oral MS-20 for moderate to severe ulcerative colitis
This trial studies whether an oral treatment called MS-20 can improve ulcerative colitis (UC) in adults with moderate to severe disease. You may be asked to provide stool samples from home and avoid certain foods and medicines before screening and during the study.
TaipeiAges 20–65 - NCT05739864RecruitingPhase 1/Phase 2
Test of donor gut bacteria for ulcerative colitis
This early-stage study tests whether a one-time transfer of “donor gut bacteria” can improve ulcerative colitis. It’s designed for people with mild to moderate ulcerative colitis who are stable on maintenance treatment.
Rome, LazioAges 18–75 - NCT05679622Recruiting
Stool transplant study for children with mild to moderate ulcerative colitis
This trial studies whether transferring healthy stool bacteria into the gut (fecal microbiota transplantation, or FMT) can improve symptoms in children with ulcerative colitis. It may help by changing gut bacteria, especially for children who are newly diagnosed or who didn’t respond to standard treatments.
WuhanAges 2–16 - NCT06420375RecruitingPhase 2
New treatment for active ulcerative colitis
This trial tests a new treatment for people with ulcerative colitis (UC) whose disease is active despite taking only mesalamine or sulfasalazine. It aims to find a therapy that can reduce inflammation and improve symptoms.
Chestnut Hill, MassachusettsAges 18–75 - NCT06784323Recruiting
Anti-inflammatory diet for Americans with ulcerative colitis
This trial tests whether a tailored anti-inflammatory diet based on American foods can help people with mild to moderately active ulcerative colitis. You'll follow a special meal plan with foods like soup, smoothies, salmon, and avocado, and researchers will track your symptoms and inflammation.
Miami, FloridaAges 16–75 - NCT06838845Recruiting
A study on upadacitinib for Chinese adults with moderate to severe ulcerative colitis
This study is looking at how well the drug upadacitinib works and how safe it is for Chinese adults with moderate to severe ulcerative colitis. It is not a treatment trial, but will observe patients who are already taking upadacitinib as decided by their doctor.
Guangzhou, GuangdongAges 18 years+ - NCT07265570RecruitingPhase 2
ISM5411 for active ulcerative colitis
This trial tests an experimental drug (ISM5411) for people with active ulcerative colitis. The goal is to see if the drug can reduce inflammation and improve symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07269223Recruiting
Oral vitamin D3 for inflammation in ulcerative colitis
This study tests whether taking vitamin D3 by mouth can reduce inflammation in people with moderate ulcerative colitis and low vitamin D levels. It may help if you have a confirmed diagnosis and are between 20–40 years old.
Lahore, Punjab ProvinceAges 20–40 - NCT02421705Recruiting
Brain-gut sensitivity study in IBS and inflammatory bowel disease
This study checks how sensitive your gut is to normal stimuli in people with IBS, ulcerative colitis, Crohn’s disease, and in healthy volunteers. Results may help researchers understand why some people feel more abdominal discomfort and how that connects to inflammatory bowel conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT07401680RecruitingPhase 1
Stool transplant for active ulcerative colitis
This trial tests whether a stool transplant (fecal microbiota transplantation) can help manage active ulcerative colitis. You would receive a transplant from a healthy donor to see if it improves your symptoms.
Calgary, AlbertaAges 18 years+ - NCT07428629Recruiting
Insomnia treatment trial for people with ulcerative colitis
This trial tests whether a sleep-focused therapy can help people with active ulcerative colitis who also have trouble sleeping. It aims to improve both sleep and UC symptoms.
Lebanon, New HampshireAges 18 years+ - NCT07662902Enrolling by invitation
Gut Barrier Study in Ulcerative Colitis Remission
This study looks at gut barrier function in people with ulcerative colitis who are in remission. It uses a non-invasive liver test to check for subtle changes in the body.
ZagrebAges 18–70 - NCT07095634Enrolling by invitation
Heart risk study for Crohn's and colitis patients
This study looks at heart health in people with Crohn's disease or ulcerative colitis. It aims to understand the risk of heart problems over 2 years.
San Donato Milanese, MilanAges 16 years+ - NCT04373473RecruitingPhase 2
Oral stool treatment to prevent ulcerative colitis flare-ups
This study tests whether taking freeze-dried (lyophilized) donor stool material by mouth can help prevent ulcerative colitis from coming back or causing intestinal inflammation. Participants are in remission and stay on their usual treatment while receiving the study product.
Houston, TexasAges 18 years+ - NCT07606339Recruiting
Guselkumab for moderate-to-severe Crohn's or ulcerative colitis
This study tests guselkumab, a medication that reduces inflammation in the gut, for people with moderate-to-severe Crohn's disease or ulcerative colitis who haven't previously tried certain similar biologic drugs. The goal is to see how well it works and is tolerated in real-world use.
ViennaAges 18 years+ - NCT04183608RecruitingPhase 4
Telemonitoring and education to guide treatment for ulcerative colitis
This trial tests whether “treat-to-target” care—guided by regular symptom checks, telemonitoring, and patient education—works better than standard follow-up when starting adalimumab for ulcerative colitis. It aims to help control inflammation more effectively and reduce flare-ups.
Cholet, Maine Et LoireAges 18–75 - NCT04372108Recruiting
Long-term safety study for ustekinumab vs other biologics
This study follows adults with Crohn’s disease or ulcerative colitis to compare the long-term safety of ustekinumab against other biologic medicines. It may help show how safe these treatments are over time, using medical records.
Portsmouth, VirginiaAges 18 years+ - NCT06495658Recruiting
Prebiotics for ulcerative colitis symptoms
This trial tests whether a prebiotic supplement can improve symptoms of ulcerative colitis. It may be a good option for people with active symptoms who are already on stable medications.
Los Angeles, CaliforniaAges 18–85 - NCT07546097RecruitingPhase 4
Upadacitinib vs Steroids for Severe Ulcerative Colitis
This study compares a newer medication called upadacitinib to traditional steroids for treating acute severe ulcerative colitis (sudden worsening of UC with bloody diarrhea and urgent symptoms). The goal is to see which approach works better as a first treatment.
Ankang, ShaanxiAges 18–85 - NCT07550673RecruitingPhase 4
Upadacitinib vs. Infliximab for Severe Ulcerative Colitis
This study compares two medications—upadacitinib and infliximab—as second-line treatments for acute severe ulcerative colitis (a serious flare of inflammatory bowel disease). The trial will help doctors understand which treatment works better when standard first-line therapy hasn't controlled the inflammation.
Ankang, ShaanxiAges 18–85 - NCT05953402Recruiting
Testing ozanimod use in pregnant people with ulcerative colitis
This trial studies how ozanimod affects pregnant people with ulcerative colitis and their babies. It may help doctors understand safety and outcomes when this medicine is used during pregnancy and after birth.
Wilmington, North CarolinaAges Any age
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Common questions
- Are there clinical trials for ulcerative colitis?
- Yes. Clin2 currently lists 293 recruiting ulcerative colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ulcerative colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ulcerative colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.