Clinical trials
Ulcerative Colitis clinical trials
Below are recruiting ulcerative colitis clinical trials, each written for real people, not researchers. We’re tracking 293 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07155148Recruiting
Argentine registry for Crohn's and colitis patients
This study collects information from people diagnosed with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. By joining the registry, you help researchers learn more about these conditions and improve care.
Córdoba, Córdoba ProvinceAges Any age - NCT07775352Recruiting
Ultrasound-guided care for inflammatory bowel disease
This study tests whether using ultrasound to guide treatment can help manage inflammatory bowel disease. You may join if you are having an endoscopy to assess your disease.
BangkokAges 18 years+ - NCT07767370RecruitingEarly Phase 1
Two experimental drugs for chronic inflammatory diarrhea
This study tests two experimental capsules, ND-12 and H-6, given together to adults with long-term diarrhea caused by inflammation in the gut, such as active ulcerative colitis. It aims to see if the combination is safe and helps reduce diarrhea and inflammation.
Nanjing, JiangsuAges 18–75 - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Birmingham, AlabamaAges 18 years+ - NCT07686757Enrolling by invitationPhase 4
Study of mirikizumab for ulcerative colitis and Crohn's disease
This study tests a new medicine called mirikizumab for people with ulcerative colitis or Crohn's disease who have not responded well to other treatments. It aims to see if mirikizumab can help control symptoms and improve quality of life.
Sun City, ArizonaAges 21 years+ - NCT07034443Recruiting
Magnetic stimulation for leaky bowel after J-pouch surgery
This trial tests if high-intensity focused electromagnetic stimulation can improve bowel control in people who have a J-pouch after ulcerative colitis surgery. It may help if you have leakage or incontinence.
Los Angeles, CaliforniaAges 18 years+ - NCT03571373Recruiting
Study of new childhood IBD and tracking safety
This trial collects information from children who are newly diagnosed with inflammatory bowel disease (IBD) and follows them to understand safety in real life. It may help doctors improve early diagnosis and treatment planning for kids with IBD.
RotterdamAges birth–19 years - NCT05230173Recruiting
Treat to endoscopic remission in inflammatory bowel disease
This study tests whether switching to a different treatment for inflammatory bowel disease (IBD) can achieve healing of the gut lining. It is for people whose symptoms are under control but who still have significant inflammation in their bowel.
Scottsdale, ArizonaAges 18 years+ - NCT06632691Recruiting
Virtual reality headset for rectosigmoidoscopy in ulcerative colitis
This trial tests if using a virtual reality (VR) headset during a rectosigmoidoscopy (a scope exam of the lower gut) makes the procedure more comfortable and acceptable for people with ulcerative colitis. The VR headset may help distract you and reduce discomfort during the exam.
La Roche-sur-YonAges 18 years+ - NCT06642883Recruiting
A supplement for gut health in ulcerative colitis remission
This study tests a supplement called ProLife 10 FORTE to see if it affects the natural balance of gut bacteria in people with ulcerative colitis (UC) that is in remission. If you have UC that is not active and you meet other health criteria, you may be able to join.
Padua, PaduaAges 18–75 - NCT07529236Recruiting
How Children's Bowel Disease Responds After Switching IBD Medications
This study follows children who had to stop one type of IBD medicine (anti-TNFα) because it caused a skin condition called psoriasis, and were switched to a different medicine called ustekinumab. Researchers want to see how well their bowel disease is controlled with the new treatment.
Nice, FranceAges 6–17 - NCT07435779RecruitingEarly Phase 1
CAR-T cell therapy for severe ulcerative colitis
This trial tests a new treatment using your own immune cells (called CAR-T cells) to calm down the immune attack that causes ulcerative colitis. It is for people with moderate to severe colitis who have not gotten better with standard medicines.
GuangzhouAges 18–60 - NCT06576700Recruiting
Can grape extract help repair leaky gut in ulcerative colitis?
This study tests if a substance called procyanidins (found in grape seeds and apples) can help repair leaky gut in people with ulcerative colitis (UC) that is in remission. It aims to see if improving gut barrier function can prevent future flares.
Padua, PaduaAges 18–80 - NCT07229950RecruitingPhase 2
Experimental tablet for moderate to severe Ulcerative Colitis
This trial tests an experimental tablet, HRS-7085, for people with moderate to severe Ulcerative Colitis who haven't gotten enough help from standard treatments. The goal is to see if the drug can reduce inflammation and improve symptoms.
Chengdu, SichuanAges 18–75 - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+ - NCT07507513RecruitingPhase 2
New drug for moderate to severe ulcerative colitis
This study tests a new medication (called 627) for people with moderate to severe ulcerative colitis who haven't responded well to or couldn't tolerate other treatments. The goal is to see if it can safely reduce inflammation and improve symptoms.
Guangzhou, GuangdongAges 18–75 - NCT07456566Recruiting
Self-management help for inflammatory bowel disease
This trial tests a self-management program for people with active Crohn's disease or ulcerative colitis. It aims to improve quality of life by helping you better manage your condition.
Ann Arbor, MichiganAges 18 years+ - NCT07710287Recruiting
Using a protein test to measure inflammation in IBD
This study looks at a protein called claudin 2 in tissue samples from people with inflammatory bowel disease (IBD). The goal is to see if it can help doctors tell whether inflammation is active or inactive. This could lead to a more accurate way to check disease activity.
San Donato Milanese, MiAges 18 years+ - NCT07224113Recruiting
Reducing ultra-processed foods in teens with IBD
This study looks at whether a simple educational program can help teens with IBD eat less ultra-processed foods (like fast food and sugary snacks). Participants will learn about healthier food choices during their regular infusion visits.
Hartford, ConnecticutAges 10–21 - NCT03589183Recruiting
Gut microbiome study for ulcerative colitis and Crohn disease
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
SeoulAges Any age - NCT03809728Recruiting
Finding blood tests linked to outcomes in Crohn’s and colitis
This study looks for “biomarkers” (lab markers, like substances in blood or tissue) that may predict how Crohn’s disease or ulcerative colitis will go and how patients may respond. It may help doctors choose better monitoring or treatments in the future.
Vandœuvre-lès-NancyAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Birmingham, AlabamaAges 18 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age
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Common questions
- Are there clinical trials for ulcerative colitis?
- Yes. Clin2 currently lists 293 recruiting ulcerative colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ulcerative colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ulcerative colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.