Clinical trials
Ulcerative Colitis clinical trials
Below are recruiting ulcerative colitis clinical trials, each written for real people, not researchers. We’re tracking 280 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07532213Recruiting
Real-world outcomes of guselkumab for ulcerative colitis or Crohn's disease
This study tracks how well guselkumab (a biologic medication that blocks IL-23, a protein that drives inflammation) works for moderate-to-severe ulcerative colitis or Crohn's disease in everyday clinical practice. Researchers want to understand long-term benefits and safety in real patients.
BernAges 18 years+ - NCT07526519RecruitingPhase 1
Safety study of TL-003 for healthy adults and ulcerative colitis
This is an early-stage study testing a new drug called TL-003 to see if it's safe and how the body processes it. Researchers will first test it in healthy volunteers, then in people with ulcerative colitis (an inflammatory bowel disease) to understand if it might help reduce inflammation.
Perth, Western AustraliaAges 18–55 - NCT07529236Recruiting
How Children's Bowel Disease Responds After Switching IBD Medications
This study follows children who had to stop one type of IBD medicine (anti-TNFα) because it caused a skin condition called psoriasis, and were switched to a different medicine called ustekinumab. Researchers want to see how well their bowel disease is controlled with the new treatment.
Nice, FranceAges 6–17 - NCT06756100Recruiting
Early inflammatory bowel disease study
This trial looks at early signs of inflammatory bowel disease (IBD) in adults who have had stomach or bowel symptoms for at least 3 weeks. It aims to understand how the disease progresses.
SantiagoAges 18–100 - NCT07524244Recruiting
Ketogenic and carnivore diets for IBD and rheumatoid arthritis
This study tests whether special diets (ketogenic or carnivore/meat-based) can help reduce inflammation and symptoms in people with inflammatory bowel disease or rheumatoid arthritis. You'll follow dietary guidelines for 3 weeks, then continue in the study while researchers track how you respond.
Charlottesville, VirginiaAges 18–64 - NCT07507513RecruitingPhase 2
New drug for moderate to severe ulcerative colitis
This study tests a new medication (called 627) for people with moderate to severe ulcerative colitis who haven't responded well to or couldn't tolerate other treatments. The goal is to see if it can safely reduce inflammation and improve symptoms.
Guangzhou, GuangdongAges 18–75 - NCT07505030Enrolling by invitationPhase 1
Safety study of LYNC-101 in healthy adults
This trial tests a new medicine called LYNC-101 in healthy volunteers to see if it is safe and how the body processes it. If you are a generally healthy adult between 18 and 60, you may be able to help researchers learn about this potential treatment.
Adelaide, South AustraliaAges 3 weeks–2 months - NCT07487480Recruiting
Guselkumab for Crohn's after ustekinumab
This study looks at whether guselkumab, a different biologic medicine, can help people with Crohn's disease who have already tried ustekinumab but it didn't work well or caused side effects. It aims to see if switching to guselkumab is safe and effective.
Hangzhou, ZhejiangAges 18–75 - NCT06780683Recruiting
Testing upadacitinib for inflammatory bowel disease
This study tests a medication called upadacitinib for people with inflammatory bowel disease (ulcerative colitis or Crohn's). The goal is to see how well it works and if it's safe.
Guangzhou, GuangdongAges Any age - NCT07456566Recruiting
Self-management help for inflammatory bowel disease
This trial tests a self-management program for people with active Crohn's disease or ulcerative colitis. It aims to improve quality of life by helping you better manage your condition.
Ann Arbor, MichiganAges 18 years+ - NCT05636709Recruiting
Follow-up study for adults starting GMA for Crohn’s or colitis
This study follows adults with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) after their doctor starts a treatment called GMA. It mainly looks at safety and how patients do in real-world care, and may help doctors understand how GMA works over time.
Albacete, AlbaceteAges 18 years+ - NCT06802887Recruiting
Long-term study of ustekinumab for Crohn's and colitis
This study follows patients with Crohn's disease or ulcerative colitis who started taking ustekinumab between February 2019 and March 2021, to see how well it works over time.
Bologna, BolognaAges 18 years+ - NCT07435779RecruitingEarly Phase 1
CAR-T cell therapy for severe ulcerative colitis
This trial tests a new treatment using your own immune cells (called CAR-T cells) to calm down the immune attack that causes ulcerative colitis. It is for people with moderate to severe colitis who have not gotten better with standard medicines.
GuangzhouAges 18–60 - NCT07436910Enrolling by invitation
Quality of life in inflammatory bowel disease
This study asks people with inflammatory bowel disease to fill out questionnaires about their quality of life. It aims to learn how the condition affects daily living and well-being.
CairoAges 18 years+ - NCT07433946Recruiting
Liquid nutrition to prevent weight loss in IBD
This study tests whether adding a special liquid nutrition drink (partial enteral nutrition) to your regular diet can help prevent weight loss and muscle loss in people with Crohn's disease or ulcerative colitis who are at risk of malnutrition.
Rozzano, MilanoAges 18–65 - NCT07431983Recruiting
IBUS vs colonoscopy and enterography for UC and CD
This study compares a newer, possibly greener imaging method (IBUS) with standard colonoscopy and enterography for people with ulcerative colitis (UC) or Crohn's disease (CD). The goal is to see if IBUS is as helpful and produces less waste or carbon emissions.
Hyderabad, TelanganaAges 18–80 - NCT07389161Recruiting
Nutrition and lifestyle triggers in IBD
This study looks at how diet and lifestyle may affect flare-ups in people with moderate inflammatory bowel disease (IBD). It aims to identify factors that can trigger symptoms.
MalmöAges 18–35 - NCT07385131Recruiting
Steroid before infliximab for inflammatory bowel disease
This study tests whether giving a steroid (dexamethasone) before an infliximab infusion can prevent allergic reactions in people with moderate-to-severe Crohn's disease or ulcerative colitis. If you qualify, you will receive either the steroid or a placebo before your infliximab treatment.
Hangzhou, ZhejiangAges 14–80 - NCT07383844Recruiting
Physical activity for teens with IBD
This study looks at what helps or stops teenagers with inflammatory bowel disease (Crohn's disease or ulcerative colitis) from being physically active. It involves completing questionnaires and an interview to understand your experience.
NiceAges 10–17 - NCT07377188Recruiting
Pregnancy and Inflammatory Bowel Disease Study
This trial looks at how pregnancy affects and is affected by inflammatory bowel disease. It aims to learn more to help women with IBD who are or want to become pregnant.
AmiensAges 18–50 - NCT07352995Enrolling by invitation
Gut temperature study during colonoscopy
This study uses a special probe to measure temperature inside the colon during a routine colonoscopy. It may help researchers understand conditions like IBD, Crohn's disease, and ulcerative colitis.
Boston, MassachusettsAges 18 years+ - NCT06758024Recruiting
Optimizing infliximab for inflammatory bowel disease
This trial tests whether closely monitoring and adjusting infliximab (a biologic medicine) can help people hospitalized with a moderate-to-severe flare of Crohn's disease, ulcerative colitis, or unclassified inflammatory bowel disease who haven't gotten better with IV steroids. The goal is to improve treatment response and outcomes.
SantiagoAges 18–75 - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT05574387RecruitingPhase 2
Metformin added to treatment for ulcerative colitis
This Phase 2 study tests whether adding metformin to usual care can help people with mild to moderate ulcerative colitis. The goal is to see if it improves symptoms and disease control compared with standard therapy alone.
Al MansurahAges 18–75
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Common questions
- Are there clinical trials for ulcerative colitis?
- Yes. Clin2 currently lists 280 recruiting ulcerative colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ulcerative colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ulcerative colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.