Clinical trials
Vaccination clinical trials
Below are recruiting vaccination clinical trials, each written for real people, not researchers. We’re tracking 602 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05242965RecruitingPhase 2
STEMVAC vaccine with pembrolizumab for advanced lung cancer
This trial tests a cancer vaccine called STEMVAC for people with advanced non-small cell lung cancer. The vaccine is given along with ongoing maintenance immunotherapy (pembrolizumab) to see if it can help keep the cancer from growing.
Omaha, NebraskaAges 18 years+ - NCT06316297RecruitingPhase 1/Phase 2
Testing a new mRNA vaccine for moderate to severe acne
This study tests an experimental mRNA vaccine designed to help the immune system fight acne-causing bacteria. It's for adults with moderate or severe facial acne who are otherwise healthy, and it may offer a new way to treat acne beyond typical creams or pills.
Scottsdale, ArizonaAges 18–45 - NCT04948619RecruitingPhase 2
Vaccine response after cancer therapy in kids
This study is checking how well the immune system works and responds to vaccines in children and young adults who have recently finished cancer treatment. It may help doctors understand if vaccines are safe and effective after therapy.
Charlotte, North CarolinaAges 2–21 - NCT07675785RecruitingPhase 2
Malaria Vaccine Study for Women Who Could Become Pregnant in Mali
This study tests an experimental malaria vaccine called PfSPZ-LARC2. Researchers want to learn if it is safe and effective for women who could become pregnant, especially in Mali where malaria is common. You would receive several doses of the vaccine and be followed for a few months.
BamakoAges 18–38 - NCT05098210RecruitingPhase 1
Personalized vaccine made from your tumor’s new immune targets
This Phase 1 study tests a customized vaccine made from “neo-antigens,” which are new targets found in your tumor. It aims to help your immune system fight certain advanced cancers that have not responded well to prior treatment.
Seattle, WashingtonAges 18 years+ - NCT04348747RecruitingPhase 2
Vaccine plus pembrolizumab for breast cancer in the brain
This trial studies whether a personalized immune-cell vaccine (dendritic cell vaccine) combined with pembrolizumab can help control brain metastases from certain types of breast cancer. It may help your immune system better recognize and attack cancer cells in the brain.
Tampa, FloridaAges 18 years+ - NCT07414524Enrolling by invitation
Pregnancy safety study of the VLA1553 vaccine
This study follows pregnant women who received the VLA1553 vaccine (for chikungunya) to see how it affects them and their babies. It compares them to pregnant women who received a different vaccine approved during pregnancy.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06529822RecruitingPhase 1
Personalized cancer vaccine for solid tumors with MRD
This trial tests a personalized cancer vaccine for people with certain cancers (bladder, stomach/esophagus, melanoma, or lung) who have no visible cancer after surgery but still have tiny bits of cancer DNA in their blood (called MRD). The vaccine is designed to train your immune system to attack any remaining cancer cells.
Orlando, FloridaAges 18 years+ - NCT06891950RecruitingPhase 3
Dengue vaccine study for healthy older adults
This trial tests a new dengue vaccine in adults aged 40 to 79 to see if it can protect them from dengue fever. If you are generally healthy and willing to follow the study schedule, you may be able to join.
Curitiba, ParanáAges 40–79 - NCT05799144RecruitingPhase 2
Pembrolizumab plus investigational HPV drugs for throat cancer
This Phase 2 trial studies pembrolizumab (an immune therapy) combined with investigational treatment(s) pBI-11 and TA-HPV for advanced or recurrent oropharyngeal cancer that is HPV-positive and has certain immune marker levels (PD-L1 CPS ≥ 1). It may help your immune system better attack cancer.
Birmingham, AlabamaAges 18 years+ - NCT03132311RecruitingPhase 4
Yellow fever vaccine study for certain people with HIV
This trial checks whether a yellow fever vaccine is safe and works well in adults with HIV who have relatively healthy immune function. It may help doctors understand the best way to protect people with HIV who have never had this vaccine.
Rio de JaneiroAges 18–59 - NCT03606967RecruitingPhase 2
Individualized vaccine added to standard treatment for metastatic triple-negative breast cancer
This Phase 2 trial tests whether adding a personalized cancer vaccine to durvalumab (an immunotherapy), tremelimumab (another immunotherapy), and chemotherapy can improve outcomes for people with metastatic triple-negative breast cancer. It may help your immune system recognize your specific tumor features.
Orange, CaliforniaAges 18 years+ - NCT03609398RecruitingPhase 2
Phase 2 study of a Rift Valley fever vaccine for safety
This study tests how safe a Rift Valley fever (RVF) vaccine is and how strongly it triggers the body’s immune response. You may be eligible if you are at risk of RVF exposure and your blood test shows you don’t already have strong protection.
Fort Deterick, MarylandAges 18–65 - NCT03888924RecruitingPhase 2
BCG vaccine for people with radiologically isolated syndrome
This trial tests whether a BCG vaccine can help people who have radiologically isolated syndrome (RIS), a condition where MRI scans show signs of possible multiple sclerosis before symptoms develop. The study aims to see if vaccination is safe and can change disease behavior over time.
RomeAges 18 years+ - NCT04144023RecruitingPhase 1
Vaccine before surgery for HER2-positive breast duct cancer in place
This Phase 1 study tests a vaccine (H2NVAC) given before surgery to help the body fight HER2-expressing ductal carcinoma in situ (DCIS) that has not been removed yet. Because it’s early-stage, the main goal is to check safety and learn how the treatment may work.
Jacksonville, FloridaAges 18 years+ - NCT04147078RecruitingPhase 1
Personalized immune vaccine after surgery for certain cancers
This Phase 1 study tests a personalized vaccine made for you to help your immune system after you’ve had surgery or ablation for certain cancers. It’s mainly done to check safety and see how well the vaccine can work at preventing cancer from coming back.
Chengdu, SichuanAges 18–100 - NCT04422366RecruitingPhase 3
9-valent HPV vaccine study for healthy Chinese women
This trial tests a 9-type HPV vaccine to see how well it works, how it helps the body build protection, and whether it’s safe. It’s for healthy Chinese women who have not had HPV vaccination before and meet specific health and timing requirements.
Liuzhou, GuangxiAges 20–45 - NCT04460235RecruitingPhase 4
Compare two pneumococcal vaccines in adults treated for lymphoma
This trial compares two vaccination plans to see which one works better for preventing pneumococcal infections after lymphoma chemotherapy. You may be randomly assigned to one of the vaccine strategies, and the study checks your immune response.
AngersAges 18 years+ - NCT04573140RecruitingPhase 1
RNA vaccine study for newly diagnosed adult and pediatric brain tumors
This Phase 1 trial studies an “RNA-lipid particle” vaccine given after surgery for certain newly diagnosed brain cancers (glioblastoma in adults, high-grade glioma in children/teens). The goal is to see whether the vaccine is safe and can train the immune system to fight the tumor.
Washington D.C., District of ColumbiaAges 4 years+ - NCT04579588Recruiting
Study flu vaccine immunity in people after COVID-19
This study looks at how well your immune system (your body’s infection-fighting system) responds to a flu vaccine after you’ve had COVID-19. It may help doctors understand why some people have different protection after vaccines.
Palo Alto, CaliforniaAges 9–64 - NCT04706390Recruiting
Study compares immune response after COVID infection vs vaccination
This study looks at how your immune system responds after natural COVID-19 infection compared with after COVID vaccination. It may help researchers understand how well different experiences train the body’s defenses.
BergenAges 20–100 - NCT04814446RecruitingPhase 3
Vaccine trial for stubborn warts on hands or feet
This Phase 3 trial tests a nonavalent HPV vaccine to treat long-lasting, hard-to-treat warts on the hands or feet. If you have tried standard treatments and the warts keep coming back or cause trouble, the vaccine may help your body clear the warts.
ParisAges 15 years+ - NCT04839757Recruiting
Testing a dengue vaccine plan for kids in the Caribbean
This trial looks at a dengue vaccine strategy in children ages 9 to 17 in Martinique and Guadeloupe. It may help protect kids from dengue, based on how the vaccine is accepted and how the study is carried out.
Fort-de-FranceAges 9–17 - NCT04843852RecruitingPhase 1
Test vaccine added to hepatitis B treatment
This early-phase study tests whether a hepatitis B vaccine (with an added ingredient to boost the immune response) can safely help people with long-term hepatitis B who are already on antiviral therapy. It is mainly looking at safety and how the immune system responds.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for vaccination?
- Yes. Clin2 currently lists 602 recruiting vaccination studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccination trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccination trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.