Clinical trials
Vaccination clinical trials
Below are recruiting vaccination clinical trials, each written for real people, not researchers. We’re tracking 600 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07648069RecruitingPhase 1
Personalized Cancer Vaccine Plus Immune Cell Therapy for Advanced Sarcoma
This study tests a personalized vaccine made from your tumor's unique mutations, combined with special immune cells grown from your blood, to treat advanced sarcoma (bone or soft tissue cancer) that did not respond to initial treatment. The goal is to help your immune system recognize and attack cancer cells.
Guangzhou, GuangdongAges 18–70 - NCT07655180RecruitingPhase 3
Testing a new COVID-19 vaccine with or without another vaccine
This trial tests a new COVID-19 vaccine called VYD2311, alone or with another COVID-19 vaccine, in healthy adults. The goal is to see if it is safe and helps your body fight the virus.
Overland Park, KansasAges 18–49 - NCT07164144Enrolling by invitation
School Ambassadors for Vaccine Education
This trial tests whether training students as vaccine ambassadors can improve vaccine education in schools. It may help increase vaccine knowledge and uptake among students.
Rochester, New YorkAges 5–21 - NCT07005726Enrolling by invitationPhase 4
BCG revaccination with DTP3 to reduce infant deaths in Africa
This study tests whether giving another BCG vaccine (the one for tuberculosis) at the same time as the third DTP shot can help reduce serious infections and deaths in babies in Africa. If your baby is healthy and getting their routine DTP3, this could be an option to possibly boost their overall protection.
BissauAges 3 months–6 months - NCT06763783Enrolling by invitationPhase 4
Shingles vaccine study for people with rheumatic diseases
This study offers the Shingrix shingles vaccine for free to adults with inflammatory rheumatic diseases. It compares how well the vaccine works in people taking immune-suppressing drugs versus those not taking them.
LundAges 18 years+ - NCT06484686Enrolling by invitationPhase 4
Long-term immunity study of chickenpox vaccine booster
This study follows up people who were in a previous phase 3 chickenpox vaccine trial. It checks how long protection from a booster dose lasts, by taking a blood sample.
Zhengzhou, HenanAges 8–16 - NCT05741242Enrolling by invitationPhase 1/Phase 2
Vaccine trial using customized immune targets for solid tumors
This trial tests a personalized cancer vaccine made from synthetic long peptide “neoantigens,” aiming to be safe and help the immune system fight certain solid tumors. It may fit people with pancreatic cancer after starting first-line chemotherapy, and some other solid tumors with limited options.
Beverly Hills, CaliforniaAges 12 years+ - NCT05095701Enrolling by invitationPhase 4
Study tracks lasting protection from a live chickenpox vaccine
This trial follows people who previously took a chickenpox (varicella) vaccine to see how long their immune protection lasts. It may help explain who stays protected over time and for how long.
Xuchang, HenanAges 1–17 - NCT05269381RecruitingPhase 1/Phase 2
Personalized cancer vaccine with pembrolizumab for advanced solid tumors
This trial tests a personalized vaccine made from your tumor's unique markers, combined with the drug pembrolizumab, to help your immune system fight cancer. It is for people with advanced solid tumors who have already tried standard treatments.
Jacksonville, FloridaAges 16 years+ - NCT07160244RecruitingPhase 3
GBS vaccine study for healthy pregnant women and their babies
This study tests a vaccine against Group B Streptococcus (GBS) during pregnancy to see if it can protect newborns from infection. Healthy pregnant women with a single baby can join.
Birmingham, AlabamaAges 1 day–49 years - NCT06218303RecruitingPhase 1
Vaccine for early breast cancer (DCIS)
This trial tests a vaccine that targets a protein (MUC1) found in early breast cancer cells. It's for women with ER+ DCIS who are planning surgery, to see if the vaccine can help prevent the cancer from coming back or getting worse.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07282665RecruitingPhase 3
Vaccine to prevent C. difficile infection in adults 65 and older
This study tests a vaccine that may help protect against a serious gut infection called C. difficile, which often happens after antibiotics or hospital stays. If you are 65 or older and have certain health conditions or recent antibiotic use, you may be able to join.
Athens, AlabamaAges 65 years+ - NCT07763301RecruitingPhase 1
Vaccine for advanced liver, bile duct, or pancreatic cancer
This trial is testing an investigational vaccine (YMN-136) for people with advanced liver, bile duct, or pancreatic cancer that has not responded to standard treatments or is not tolerated. The vaccine aims to help your immune system fight the cancer. It may be an option if standard treatments have failed.
Chengdu, SichuanAges 18–75 - NCT07573462RecruitingPhase 3
Safety study of a new pneumococcal vaccine for infants
This study tests whether a new pneumococcal vaccine (which protects against a serious bacterial infection) is safe in healthy 2-month-old infants. Researchers will watch for side effects and help protect future babies from pneumococcal disease.
Estero, FloridaAges 1 month–3 months - NCT06831929Recruiting
HPV vaccine encouragement for preteens
This study looks at ways to make it easier for preteens aged 10 to 12 to get the HPV vaccine, which protects against certain cancers. It aims to see if simple reminders or education can increase vaccination rates.
Sacramento, CaliforniaAges 10–12 - NCT05264974RecruitingPhase 1
Personal tumor vaccine for melanoma and soft tissue sarcoma
This trial tests a personalized vaccine made from your own tumor tissue. The goal is to help your immune system fight cancer and to improve the response to PD-1 inhibitor therapy.
Gainesville, FloridaAges 18–99 - NCT02471378Recruiting
Testing a malaria vaccine in pregnant people with malaria
This study looks at lab tests for malaria vaccine candidates in pregnant women who currently have malaria. It may help researchers understand which vaccine approaches are safest and most promising for pregnancy.
BamakoAges 15–25 - NCT07749911Recruiting
Vaccine effectiveness study for malaria in young children
This study looks at how well the R21/Matrix-M malaria vaccine works in real-life settings for children under 5. If your child is eligible for the vaccine and has a fever, they may be able to join and help us understand the vaccine's impact.
Boromo, Boucle MouhounAges 5 months–5 years - NCT07572864RecruitingPhase 2
Immunotherapy and vaccine before surgery for head and neck cancer
This trial tests a new combination of immunotherapy (a drug that helps your immune system fight cancer) and a mitochondrial vaccine given before surgery for head and neck squamous cell carcinoma. The goal is to help reduce cancer recurrence and improve survival after surgery.
Chengdu, SichuanAges 18 years+ - NCT06195384RecruitingPhase 1
Personalized mRNA vaccine for advanced solid tumors
This trial tests a personalized mRNA vaccine made from your tumor's unique markers (neoantigens) to train your immune system to fight cancer. It is for people with advanced solid tumors who have not had gene therapy and are healthy enough for the vaccine.
Guangzhou, GuangdongAges 18–75 - NCT07495124RecruitingPhase 2
IGFBP-2 vaccine to prevent ovarian cancer return
This trial tests a vaccine that targets a protein called IGFBP-2 to prevent ovarian cancer from coming back. It is for people whose CA-125 blood test shows the cancer might be returning, but who don't yet have tumors visible on scans.
Seattle, WashingtonAges 18 years+ - NCT05916248RecruitingEarly Phase 1
mRNA vaccine plus pembrolizumab for advanced solid tumors
This trial tests whether a personalized mRNA vaccine, given with pembrolizumab, can help people with advanced solid tumors by training the immune system to recognize cancer. It is mainly for patients whose tumor tissue matches specific genetic and immune patterns, and who meet key safety and infection requirements.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04871932Recruiting
Study of immune response to a COVID-19 vaccine
This trial studies how your immune system responds after a COVID-19 vaccine. It uses detailed blood tests to understand what changes happen in your immune cells and may help researchers improve future vaccines.
ShanghaiAges 18–50 - NCT07104240Recruiting
Improving HPV vaccination for preteens ages 9-12
This study tests a program designed to help primary care practices increase HPV vaccination rates among adolescents aged 9 to 12 who haven't yet been vaccinated. It aims to find out if providing practices with resources and support can lead to more kids getting the HPV vaccine.
Atlanta, GeorgiaAges 9 years+
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Common questions
- Are there clinical trials for vaccination?
- Yes. Clin2 currently lists 600 recruiting vaccination studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaccination trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaccination trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.