Treatment
Bupivacaine clinical trials
We’re tracking 206 recruiting studies that include Bupivacaine, each written for real people, not researchers, below.
Recruiting studies
- NCT07509866Recruiting
Comparing pain relief options for knee replacement surgery
This trial tests two different numbing medicines for knee replacement surgery. It compares a long-acting numbing medicine (liposomal bupivacaine) with a standard one (ropivacaine) mixed with other drugs to see which provides better pain control. The goal is to find a way to reduce pain and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07465185RecruitingPhase 2
Testing a drug for cesarean delivery pain relief
This study compares a standard spinal anesthetic (bupivacaine) with or without an added drug (dexmedetomidine) to see which works better for pain relief during planned cesarean delivery. It may help find a safer or more effective option for mothers.
Banhā, Elqalyoubea,Ages 20–35 - NCT07693621Recruiting
Pain relief medicine added to numbing drug for gallbladder surgery
This trial tests if adding dexmedetomidine or magnesium to a standard numbing medication (bupivacaine) injected into the belly during gallbladder surgery can improve pain control and recovery. It aims to find a better way to manage pain after surgery.
AlexandriaAges 18–60 - NCT06529432RecruitingPhase 2
Study of a long-acting painkiller for lung surgery recovery
This trial tests a long-acting pain medication (bupivacaine liposome injection) to control pain after lung surgery done through a small cut. It may help you feel more comfortable and reduce the need for other pain medicines.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06956950RecruitingPhase 2/Phase 3
Magnesium Added to Numbing Medicine for Hip Replacement Pain
This study tests whether adding magnesium sulfate to a numbing medicine (bupivacaine) can provide better pain relief after hip replacement surgery. The medicine is given as a shot in the back near the hip muscles.
Tanta, El-GharbiaAges 18 years+ - NCT06942689RecruitingPhase 4
Finding the best dose of numbing medicine for knee surgery pain
This trial tests different amounts of a long-lasting numbing medicine (liposomal bupivacaine) injected near the nerve in your thigh to see which volume works best for controlling pain after knee surgery. If you qualify, you may receive better pain relief and need fewer opioids.
Nanjing, JiangsuAges 18–85 - NCT07648784Recruiting
Pain Relief Comparison for Lower Leg Surgery
This trial tests different combinations of two numbing medicines (lidocaine and bupivacaine) given through the spine to manage pain during lower limb surgery. The goal is to find which mixture works best and lasts longest.
Karachi, SindhAges 20–60 - NCT07141589Recruiting
Comparing pain relievers added to numbing for eye surgery
This study compares two medicines (fentanyl and ketorolac) added to the numbing injection used during eye surgery. The goal is to see which one works better to reduce pain and make the surgery more comfortable.
CairoAges 18 years+ - NCT03737292RecruitingPhase 4
Numbing medicine for chest surgery pain after small lung operations
This trial tests whether a long-lasting numbing shot (liposomal bupivacaine) works better than a regular numbing shot (plain bupivacaine) for pain after minimally invasive chest surgery. It may help you have less post-surgery pain and potentially use less pain medication.
Hershey, PennsylvaniaAges 18 years+ - NCT04951804Recruiting
EUS pain block for pancreatic cancer, with or without bupivacaine
This trial tests whether a nerve-blocking procedure during an endoscopy can reduce pain from pancreatic cancer. Participants will get the procedure either with or without bupivacaine, a local numbing medicine.
Montreal, QuebecAges 18 years+ - NCT06252662RecruitingPhase 4
Comparing two numbing medicines for mastectomy nerve blocks
This study compares two types of numbing medicine given through a nerve block before a mastectomy. One is a long-acting version (liposomal bupivacaine) and the other is a standard numbing medicine combined with a sedative (bupivacaine with dexmedetomidine). The goal is to see which provides better pain relief after surgery.
Portsmouth, VirginiaAges 18 years+ - NCT06284434RecruitingPhase 3
EXPAREL for pain after cleft gum repair
This trial tests if a long-lasting numbing medicine (EXPAREL) can help control pain after surgery to repair the gum in children and adults with cleft lip or palate. It may mean less discomfort after the procedure.
Chicago, IllinoisAges 6 years+ - NCT06411795RecruitingPhase 2
Comparing two pain relief methods after Whipple surgery
This study compares two ways to manage pain after Whipple surgery: a long-lasting numbing injection near the belly muscles (rectus sheath block) versus an epidural (a tube placed in your back). The goal is to see which method provides better pain relief and recovery.
Minneapolis, MinnesotaAges 18 years+ - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT04908579RecruitingPhase 4
Preventive ketamine to reduce pain after surgery
This study tests whether giving ketamine before or during surgery can reduce pain afterward. It is designed for adults with higher body weight who also have certain health conditions like well-controlled diabetes or blood pressure.
CairoAges 21–60 - NCT06993922Recruiting
Scalp block with added sedative for brain surgery pain
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
CairoAges 18–65 - NCT07088900Recruiting
Dexmedetomidine with bupivacaine for pain relief in children's appendix surgery
This trial tests if adding dexmedetomidine to bupivacaine (a numbing medicine given near the tailbone) provides better pain relief during and after appendix surgery in children. It may help reduce the need for other pain medicines.
CairoAges 2–7 - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT07212114RecruitingPhase 3
Comparing two numbing medicines for ankle replacement
This study compares two numbing medicines given during ankle replacement surgery to see which one works better for controlling pain after the operation. It may help you have less pain and need fewer pain pills afterward.
Atlanta, GeorgiaAges 18 years+ - NCT07232108Recruiting
Pain medicine options for recovery after laparoscopic hysterectomy
This study compares two types of pain medicine given during laparoscopic hysterectomy: one is a morphine shot into the spine, the other is numbing medicine injected around the surgery cuts and into the belly. The goal is to see which helps you recover better and with less pain.
ErzurumAges 18–65 - NCT07285083Recruiting
Pain relief after abdominal surgery: comparing two numbing medicines
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
Rahim Yar Khan, Punjab ProvinceAges 21–45 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT07590752RecruitingPhase 2/Phase 3
Pain Relief Comparison for Abdominal Surgery
This trial compares two medications added to a numbing injection around your abdominal muscles during belly surgery to help manage pain after surgery. The study aims to find which combination works better and lasts longer.
Sahiwal, Punjab ProvinceAges 25–65 - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99
Common questions
- Are there clinical trials studying Bupivacaine?
- Yes. Clin2 currently lists 206 recruiting studies that include Bupivacaine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Bupivacaine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Bupivacaine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Bupivacaine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.