Treatment
Bupivacaine clinical trials
We’re tracking 206 recruiting studies that include Bupivacaine, each written for real people, not researchers, below.
Recruiting studies
- NCT07324499Recruiting
Dexamethasone with nerve block for shoulder surgery
This trial tests if adding dexamethasone to a standard numbing medicine (bupivacaine) affects how much of the medicine stays in your blood. It may help improve pain relief after shoulder surgery.
SantiagoAges 18–90 - NCT06972680Enrolling by invitation
Finding the best dose for a shoulder block before surgery
This trial tests different volumes of a long-lasting numbing medicine (Exparel) injected around the shoulder nerves before arthroscopic surgery. The goal is to find the dose that provides the best pain relief.
Jiaxing, ZhejiangAges 18 years+ - NCT03906617RecruitingPhase 4
Pain-relief shots for lung surgery: three drug options compared
This study compares different pain-relief medications given during lung surgery to see which one controls pain better. It may help people have less post-surgery pain after robotic wedge resection or lobectomy.
Camden, New JerseyAges 18–90 - NCT07139522Recruiting
Dexamethasone or magnesium for pain relief after C-section
This trial tests adding dexamethasone or magnesium sulfate to the numbing medicine given as a back injection (erector spinae plane block) to see if it provides better pain relief after a planned C-section. The goal is to reduce pain and the need for extra painkillers after surgery.
CairoAges 18–35 - NCT05425979Enrolling by invitationPhase 4
Compare numbing medicines for ankle blocks in foot surgery
This study tests which numbing medicine works faster for an ultrasound-guided ankle nerve block during foot surgery: mepivacaine or bupivacaine. It may help improve comfort by reducing how long it takes for the numbness to start.
Rochester, MinnesotaAges 18 years+ - NCT07386327Recruiting
Comparing diluted bupivacaine for arm surgery nerve block
This trial tests whether mixing the numbing medicine bupivacaine with sugar water (dextrose) or salt water (saline) affects how well a nerve block works for upper arm surgery. The goal is to find which mixture provides better pain relief with fewer side effects.
SakaryaAges 18–65 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT07108465RecruitingEarly Phase 1
Anesthetic comparison for wisdom tooth removal
This trial compares two numbing medicines, bupivacaine and ropivacaine, to see which works better for removing impacted lower wisdom teeth during general anesthesia. It may help determine which option provides better pain relief after surgery.
Porto Alegre, Rio Grande do SulAges 18–60 - NCT07013955Enrolling by invitationPhase 3
Comparing nasal packing drugs for better sinus surgery view
This trial is testing whether packing the nose with one of three medications (dexmedetomidine, midazolam, or bupivacaine) during functional endoscopic sinus surgery (FESS) can improve the surgeon's view during the procedure. It may help patients by reducing bleeding and making the surgery smoother.
MinyaAges 16–60 - NCT05824338RecruitingEarly Phase 1
Testing ropivacaine spinal anesthesia for lower back surgery
This early study tests whether using ropivacaine (a local numbing medicine) in spinal anesthesia is safe and workable for certain lower back operations. If you qualify, it may help doctors refine anesthesia choices for your type of surgery.
New Westminster, British ColumbiaAges 19–80 - NCT05830630Recruiting
Methylene blue given during leg amputation surgery
This trial studies whether infusing methylene blue during above- or below-knee leg amputation can improve outcomes for people with poor blood flow to the legs. It targets patients having surgery under general anesthesia, while excluding those with certain allergies or blood clotting problems.
Tanta, Gharbia GovernorateAges 18 years+ - NCT06633068RecruitingPhase 2
Pain relief study: nalbuphine added to numbing medicine for thyroid surgery
This study tests if adding nalbuphine to the numbing medicine (bupivacaine) given as a nerve block before thyroid surgery provides better pain relief. It is for adults having planned thyroid surgery.
Giza, الجيزةAges 18–60 - NCT06590402RecruitingPhase 4
Nerve blocks for pain relief after kids' knee surgery
This study compares two types of nerve blocks to manage pain after knee surgery in children and teens. It is for patients aged 8 to 18 having a first-time ACL or MPFL reconstruction.
New York, New YorkAges 8–18 - NCT06344091RecruitingPhase 4
Study of a long-lasting numbing medicine for children having orthopedic surgery
This trial tests a long-lasting numbing medicine (bupivacaine liposome injection) given during surgery to help control pain in children. It may reduce the need for other painkillers after orthopedic surgery.
Guangzhou, GuangdongAges 6–17 - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT04577690RecruitingPhase 4
PECS pain study for children getting a chest device implanted
This trial tests a pain-control method (PECS) during surgery for children who are having a small chest device implanted. It may help reduce discomfort during and after the operation.
Toronto, OntarioAges 3–18 - NCT04928352RecruitingPhase 3
Breathing numbing medicine during cleft palate surgery
This trial tests whether a breathing treatment (nebulized numbing medicine) can reduce pain during cleft palate repair in young children. It may help comfort your child after surgery when they are under general anesthesia.
Asyut, AssuitAges 1–7 - NCT04930887RecruitingPhase 2
Numbing injection in the face to ease craniofacial pain
This trial tests whether an injection of a numbing medicine (bupivacaine) guided by an endoscope can reduce craniofacial pain. It may help people with certain headache or facial pain conditions by targeting the pain area more precisely.
Stanford, CaliforniaAges 18–80 - NCT05543694RecruitingPhase 4
Testing epidural pain relief for labor
This study is testing how well a combination of two medicines (bupivacaine and lidocaine) works for epidural pain relief during early labor. The goal is to find the best dose to help manage labor pain.
Boston, MassachusettsAges 18–50 - NCT06146842RecruitingPhase 4
Pain relief study for labor epidurals
This study tests two different epidural techniques to find the best dose of pain medicine for labor. It aims to improve comfort during childbirth.
Boston, MassachusettsAges Any age - NCT05224089RecruitingPhase 4
Numbing shot comparison for pain control in laparoscopic colon surgery
This study compares two types of numbing injections (a longer-acting option versus standard numbing) placed near nerves to help control pain during laparoscopic colon surgery. It looks to see which method works better and is safe for patients having planned surgery.
Hartford, ConnecticutAges 18 years+ - NCT05750992Recruiting
Ultrasound vs surgery guidance for numbing during C-section
This trial compares two ways of placing numbing medicine (with bupivacaine) during a planned C-section: an ultrasound-guided approach versus a surgical approach. It aims to find which method provides better pain control and comfort with fewer problems.
CairoAges 21–35 - NCT05862792Recruiting
Liposomal bupivacaine during robotic throat surgery
This study gives a pain-relief medicine (bupivacaine in a slow-release form) during transoral robotic throat surgery. It aims to see if it improves comfort and pain control around the time of surgery.
Danville, PennsylvaniaAges 18 years+
Common questions
- Are there clinical trials studying Bupivacaine?
- Yes. Clin2 currently lists 206 recruiting studies that include Bupivacaine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Bupivacaine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Bupivacaine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Bupivacaine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.