Treatment
Comparator clinical trials
We’re tracking 1,757 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06538038Recruiting
Osimertinib plus chemo vs. osimertinib alone for EGFR-mutated NSCLC
This study compares two standard treatments for advanced lung cancer with an EGFR mutation: osimertinib alone versus osimertinib plus chemotherapy. It aims to see which approach works better and is not a trial of a new drug, so you can receive usual care while contributing data.
Birmingham, AlabamaAges 18 years+ - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65 - NCT06547073Recruiting
Virtual reality vs traditional exercise for frozen shoulder
This study compares virtual reality training to standard exercise therapy for people with frozen shoulder. It aims to see if VR can be more effective in reducing pain and improving movement, offering a potentially more engaging treatment option.
GhentAges 18–70 - NCT06553443RecruitingPhase 3
Comparing coated and plain balloons for dialysis access narrowing
This trial tests whether a drug-coated balloon works better than a plain balloon to open up narrowed spots in your dialysis access. If you have a failing AVF with a narrowing that can be treated, this study may help improve your dialysis.
SingaporeAges 21 years+ - NCT06558708RecruitingPhase 2
Comparing two once-daily insulins for type 2 diabetes
This trial compares two once-daily insulin injections to see which works better and is safer for people with type 2 diabetes. Both are new types of insulin designed to help control blood sugar with fewer side effects.
TianjinAges 18–75 - NCT06559826RecruitingPhase 2
Ketamine therapy with or without talk for depression
This study compares ketamine alone to ketamine combined with psychotherapy for treating depression. It may help if you have moderate to severe depression and want to see if adding talk therapy improves results.
New York, New YorkAges 18–90 - NCT06560671Recruiting
App vs. paper for colonoscopy prep education
This study compares a new smartphone app to standard paper instructions for helping patients get their bowel ready for colonoscopy. It aims to see which method is easier to understand and leads to a better exam.
HsinchuAges 18 years+ - NCT06561360RecruitingPhase 2
Comparing two treatments for hairy cell leukemia
This study tests whether a combination of targeted drugs (vemurafenib and obinutuzumab) works better than a standard chemo-immunotherapy combination (cladribine and rituximab) for people newly diagnosed with hairy cell leukemia. If you have the BRAF V600E mutation and meet blood count criteria, you may be eligible to join.
Boston, MassachusettsAges 18 years+ - NCT06561854RecruitingPhase 3
Comparing multiple myeloma treatment with and without dexamethasone
This trial tests whether adding dexamethasone to an antibody-based combination therapy works better for multiple myeloma that has come back after previous treatments. If you have had 1 to 3 prior therapies and are eligible for one of two standard drug regimens, this study may help find the best approach for you.
ParisAges 18 years+ - NCT06562842Recruiting
Exercise, Gut Health, and Type 2 Diabetes Study
This study looks at how exercise affects gut bacteria in people with type 2 diabetes. It may help explain why physical activity improves diabetes control.
TrikalaAges 45–65 - NCT06564324RecruitingPhase 3
Comparing taletrectinib to standard therapy for ROS1-positive lung cancer
This study compares a new targeted therapy pill (taletrectinib) to standard treatments for people with advanced ROS1-positive lung cancer. The goal is to see if taletrectinib works better at shrinking tumors and delaying cancer growth.
Hefei, AnhuiAges 18 years+ - NCT06566170Recruiting
Donanemab for early Alzheimer's: a real-world study
This study compares donanemab plus usual care to usual care alone for people with early Alzheimer's symptoms, to see how well donanemab works in everyday life. You may be able to join if you have early memory or thinking problems and have a brain scan or blood test showing Alzheimer's-related changes.
Huntsville, AlabamaAges 60 years+ - NCT06567522RecruitingPhase 4
Nerve block vs. no block for hip surgery pain
This trial compares a lumbar erector spinae plane block (L-ESPB), a type of nerve numbing injection, to not using any block for managing pain after hip surgery. The goal is to see which approach works better and is safer.
Vigo, PontevedraAges 18 years+ - NCT06570980Recruiting
Comparing two diabetes drugs taken with metformin
This study looks at two common diabetes pills (sulfonylureas and DPP4 inhibitors) when used together with metformin. It aims to find out which combination is more cost-effective for treating type 2 diabetes.
DhakaAges 18 years+ - NCT06573008RecruitingPhase 3
Testing GP681 Tablets for Flu in High-Risk Patients
This study tests an oral tablet called GP681 for people with flu who are at higher risk of serious complications. It compares the new drug to a placebo to see if it helps reduce symptoms faster.
ChizhouAges 12 years+ - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT06580327Recruiting
Epidural Drip vs. Intermittent Doses for Women in Labor
This study compares two ways of giving epidural pain medicine during labor—continuous drip versus intermittent doses. It is for women who have given birth before and are in early labor with a single, head-down baby.
NazarethAges Any age - NCT06582706RecruitingPhase 1/Phase 2
Vitamin B3 (niacin) for Alzheimer's disease
This study tests if nicotinic acid (a form of vitamin B3) can help people with mild to moderate Alzheimer's disease. It involves taking a daily pill, having a lumbar puncture, and regular check-ups to see if the vitamin improves thinking and memory.
Indianapolis, IndianaAges 60–85 - NCT06584409Recruiting
Laser Acupuncture vs Standard for Migraine – Blood Test Study
This trial tests whether laser acupuncture can help migraines by checking two substances in your blood (MMP2 and CGRP). You may be able to join if you have migraines and are not pregnant.
Taichung, TaichangAges 18 years+ - NCT06590714Recruiting
Polmacoxib for pain after rotator cuff surgery
This trial tests if Polmacoxib, an anti-inflammatory drug, can reduce the need for stronger painkillers after rotator cuff surgery. It may help manage pain with fewer side effects.
Uijeongbu-si, Gyeonggi-doAges 18 years+ - NCT06592833RecruitingPhase 2
Psilocybin with or without pimavanserin for depression
This study tests whether combining psilocybin (a psychedelic substance) with pimavanserin (a medication that may help reduce side effects) works better than psilocybin alone for treating major depressive disorder. It may help people who have not responded well to other treatments.
New York, New YorkAges 21–80 - NCT06593184Recruiting
Magnetic stimulation for mobility after stroke
This trial tests a non-invasive treatment called trans-spinal magnetic stimulation to help improve walking and movement in people who have had a stroke. It is for those with trouble walking and are at least 6 months past their stroke.
João Pessoa, ParaíbaAges 18–75 - NCT06595836Recruiting
Comparing a new synthetic condom to a standard latex condom
This trial tests if a new type of condom made from synthetic polyisoprene works as well as a natural rubber latex condom. You and your partner will use both types during vaginal intercourse and share your feedback.
Berkeley, CaliforniaAges 18–45 - NCT06596772RecruitingPhase 3
Comparing a biosimilar to Enbrel for rheumatoid arthritis
This trial tests if a new biosimilar called MB04 works as well as the standard drug Enbrel for people with moderate to severe rheumatoid arthritis. Participants will keep taking methotrexate while being assigned to one of the two drugs to see how they compare.
HaskovoAges 18–75
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,757 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.