Treatment
COVID-19 vaccine clinical trials
We’re tracking 62 recruiting studies that include COVID-19 vaccine, each written for real people, not researchers, below.
Recruiting studies
- NCT07861542RecruitingPhase 4
COVID-19 booster vaccine for older adults and high-risk people
This trial tests an updated COVID-19 booster vaccine designed to improve protection for people who are older or have health conditions that increase their risk of severe COVID-19. If you qualify, you would receive one dose of the study vaccine and be monitored for safety and immune response.
Fair Oaks, CaliforniaAges 12 years+ - NCT07838038Recruiting
COVID-19 vaccine reminder messages for Kaiser Permanente members
This study tests whether different email messages can encourage people to get the updated COVID-19 vaccine. If you join, you'll be part of a Kaiser Permanente program that sends you reminders to help you stay protected.
Pasadena, CaliforniaAges 18 years+ - NCT04834869Recruiting
Track safety after COVID-19 vaccination in adults
This study follows adults who have already received a COVID-19 vaccine to monitor side effects and safety over time. Your participation helps researchers understand how the vaccine affects different people who are at higher risk due to their work.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06168032Recruiting
COVID-19 vaccine for lung cancer patients
This trial is testing how well the COVID-19 vaccine works for people with lung cancer to prevent another infection. It also looks at certain biomarkers in your blood that might help predict your body's immune response.
BeijingAges 18 years+ - NCT04706390Recruiting
Study compares immune response after COVID infection vs vaccination
This study looks at how your immune system responds after natural COVID-19 infection compared with after COVID vaccination. It may help researchers understand how well different experiences train the body’s defenses.
BergenAges 20–100 - NCT07798648RecruitingPhase 3
COVID-19 vaccine study for children and adults
This study tests a COVID-19 vaccine in children and adults. It may help protect against COVID-19.
Homestead, FloridaAges 5 years+ - NCT05218356RecruitingPhase 2
Codivir trial for hospitalized moderate COVID-19
This trial tests whether Codivir can help people hospitalized with moderate COVID-19 recover better than a placebo (inactive pill). It will compare outcomes while participants receive standard hospital care.
Paulo Prata, Barretos/SP/BRAAges 18–75 - NCT07730450RecruitingPhase 4
COVID-19 vaccine study for healthy adults aged 18 to 64
This trial tests a COVID-19 vaccine in healthy adults to see how well it works. It may be an option if you are not at higher risk for severe COVID-19 and have not had COVID-19 in the past 6 months.
Walnut Creek, CaliforniaAges 18–64 - NCT06441955RecruitingPhase 4
Long Covid prevention and health support trial
This trial tests a care program designed to help people who continue to have symptoms after recovering from COVID-19. It aims to prevent long-term health problems and improve well-being.
Bethesda, MarylandAges 18–65 - NCT07464314RecruitingPhase 1
Testing a combined flu and COVID-19 mRNA vaccine in older adults
This trial is testing whether a new mRNA vaccine that targets both seasonal flu and COVID-19 is safe and creates a strong immune response. It may offer an easier way to protect against two illnesses with one shot.
Anniston, AlabamaAges 65–85 - NCT07445971RecruitingPhase 1
Study of MDX2301 for healthy adults and those at higher risk for severe COVID-19
This trial tests an investigational drug called MDX2301 to see if it's safe in healthy adults and in adults who are at higher risk for severe COVID-19. Higher risk means you have conditions like asthma, diabetes, heart disease, or other listed health issues.
Las Vegas, NevadaAges 18–64 - NCT05553743Recruiting
Study of donated breast milk and how it affects child health
This study looks at breast milk donated for research and how it may relate to infant and child health. If you’re an adult who is breastfeeding and can donate extra milk, you may be able to participate.
San Diego, CaliforniaAges 18 years+ - NCT07400848Recruiting
Symptoms and recovery after COVID-19 vaccine
This study looks at people who developed new, long-lasting symptoms after a COVID-19 vaccine. It aims to understand their symptoms, do lab tests, and see how they recover over time.
BernAges 18 years+ - NCT06255626RecruitingPhase 1/Phase 2
New COVID-19 booster vaccine study
This trial tests a new type of COVID-19 booster vaccine that targets a protein to help your immune system. It's for people who already had a primary vaccine series and at least one mRNA booster, with the last booster at least 6 months ago.
CréteilAges 18–84 - NCT06960928RecruitingPhase 3
Low dose sirolimus for long COVID
This trial tests if a low dose of sirolimus, a medicine that calms the immune system, can help people with long COVID. If you have had long COVID symptoms for at least 6 months, like severe fatigue, brain fog, or chest pain, you may be able to join.
New York, New YorkAges 18 years+ - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100 - NCT06599658RecruitingPhase 2
COVID-19 booster and flu vaccine timing for people with weak immune systems
This study tests the best timing for a COVID-19 booster and flu shot in people with weakened immune systems, such as organ transplant recipients, people living with HIV, or those with certain autoimmune conditions. It aims to help patients get better protection from both vaccines.
Montreal, QuebecAges 18 years+ - NCT06469788Recruiting
COVID-19 vaccine navigation for rheumatology patients
This study looks at helping Black and Latinx adults with autoimmune rheumatic diseases get the updated COVID-19 vaccine. It offers information and support (like testimonials and navigation help) to see what works best.
Birmingham, AlabamaAges 18 years+ - NCT06355232RecruitingPhase 1
Oral vaccine for COVID-19 and flu
This study tests an experimental oral vaccine that may protect against both COVID-19 and the flu. Researchers want to see if it's safe and how the body responds.
Adelaide, South AustraliaAges 18 years+ - NCT06381739RecruitingPhase 2
New inhaled COVID-19 booster vaccine trial
This trial tests a next-generation COVID-19 vaccine given as an inhaled mist. It is for adults who have already had at least 3 doses of an mRNA COVID vaccine and are looking for a potentially stronger or longer-lasting immune response.
Halifax, Nova ScotiaAges 18–65 - NCT06128928Recruiting
Boosting COVID-19 vaccines in Latino communities
This study tests whether connecting with friends and health workers can help more Latino people in Maryland get vaccinated or boosted against COVID-19. It aims to reach both those who are already vaccinated and those who are hesitant.
Baltimore, MarylandAges 18 years+ - NCT05571735Recruiting
COVID vaccine immune response study in people with tuberculosis
This study measures how strongly your immune system responds to COVID-19 vaccines. It includes people with newly diagnosed tuberculosis and a healthier comparison group, aiming to understand vaccine immune effects and safety.
Mae Ramat, Changwat TakAges 18 years+ - NCT05415267RecruitingPhase 3
Boosting COVID protection during long-term immune suppression
This study looks at how well a COVID-19 booster works in adults who need long-term medicines that lower immune response. It aims to see whether immunosuppressed people benefit from booster vaccination safely.
Blacktown, New South WalesAges 18 years+ - NCT05212792Recruiting
Study genes after COVID vaccine side effects
This study looks at genetic information to better understand why some people develop serious side effects after a COVID-19 vaccine, such as GBS, blood clotting with low platelets (VITT/TTS), or heart inflammation (myocarditis/pericarditis). Your information may help researchers learn who is at higher risk and improve future safety.
Vancouver, British ColumbiaAges 5–99
What COVID-19 vaccine is being studied for
Conditions with recruiting COVID-19 vaccine studies.
Common questions
- Are there clinical trials studying COVID-19 vaccine?
- Yes. Clin2 currently lists 62 recruiting studies that include COVID-19 vaccine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a COVID-19 vaccine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is COVID-19 vaccine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether COVID-19 vaccine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.