Treatment
COVID-19 vaccine clinical trials
We’re tracking 68 recruiting studies that include COVID-19 vaccine, each written for real people, not researchers, below.
Recruiting studies
- NCT07651761Enrolling by invitation
Vaccine Talk Training for Primary Care Doctors
This study tests whether special training helps primary care doctors have better conversations with patients about flu and COVID-19 vaccines. You may be eligible if you're a patient who visits a participating clinic during the 2026–2027 vaccine season.
Worcester, MassachusettsAges 18 years+ - NCT06590324RecruitingPhase 2/Phase 3
Study of Apabetalone for long COVID
This trial tests an experimental drug called Apabetalone for people with long COVID. You may be eligible if you have type 2 diabetes, take or are willing to take dapagliflozin, and have had long COVID symptoms for at least 2 months after your COVID infection.
AmmanAges 18 years+ - NCT07197164RecruitingPhase 2
Remdesivir for kidney transplant patients with mild COVID-19
This trial tests whether giving remdesivir to kidney transplant patients who test positive for COVID-19 can prevent them from getting severely ill. It is for people who have already had at least three COVID-19 vaccine doses and are scheduled to receive a kidney transplant soon.
Badalona, BarcelonaAges 18 years+ - NCT05796505Recruiting
Community outreach to improve vaccine acceptance in prisons
This study tests community engagement approaches to help people in prison feel more comfortable accepting vaccines. It will focus on people in regular housing areas, and it may help increase vaccine willingness through trusted local outreach.
Schwenksville, PennsylvaniaAges 18 years+ - NCT07085611Recruiting
Studying vaccine and antibody protection in adults
This trial checks how well antibodies from COVID-19 or monkeypox vaccines or treatments work in adults. It helps researchers understand your protection level.
OrléansAges 18 years+ - NCT06810934RecruitingPhase 1/Phase 2
New COVID-19 vaccine study for those with prior mRNA vaccines
This study tests a new type of COVID-19 vaccine that is designed to train your immune system to make stronger, longer-lasting protection. You may be able to join if you are 40–64, have already had at least two doses of a mRNA COVID-19 vaccine (Pfizer or Moderna) more than 4 months ago, and are generally healthy.
Los Angeles, CaliforniaAges 40–64 - NCT04611243Recruiting
Follow-up study after hospital recovery from COVID-19
This study checks how well your lungs work and how much exercise you can do after you’ve been discharged from the hospital for COVID-19. It also measures blood (serology) results to understand recovery and possible immune response changes over time.
Hong KongAges 18 years+ - NCT05973084Recruiting
COVID spread study in Malawi households and vaccine recipients
This study tracks how COVID-19 spreads and causes illness in real households in Blantyre, Malawi, and compares groups after infection or vaccination. If you qualify, you’ll do follow-up testing and visits for several months.
Boston, MassachusettsAges 5–75 - NCT01306084Recruiting
Study of viral infections in healthy and immune-compromised people
This trial studies how viruses affect the body, and how the immune system responds, in both healthy people and people with weakened immunity. It may include people who currently have a suspected or recent viral infection, close contacts, people around the time of a viral vaccine, and healthy adults used for comparison.
Bethesda, MarylandAges 6 months–120 years - NCT07397455RecruitingPhase 1
COVID-19 Omicron Human Challenge Study
This study is a 'human challenge' trial where healthy volunteers who have been vaccinated and have low antibody levels are deliberately exposed to a newer Omicron variant of COVID-19. The goal is to learn how the virus spreads and how to test treatments or vaccines.
LondonAges 18–50 - NCT04815096RecruitingPhase 2
PET scan study of immune activity after COVID-19
This Phase 2 study uses a special PET scan to look at how active your immune system is after a recent COVID-19 infection. The goal is to understand what the immune response looks like and whether this imaging approach could help guide care.
San Francisco, CaliforniaAges 18 years+ - NCT05141058RecruitingPhase 1
T cell therapy to help prevent COVID-19 after transplant
This Phase 1 trial tests a donated immune-cell treatment (T cells) to help immunocompromised people fight or resist COVID-19 after they recently received a bone marrow or stem cell transplant. It aims to see if the treatment is safe and if it helps the body respond better to the virus.
Washington D.C., District of ColumbiaAges 2–80 - NCT05384509Recruiting
Tracking antibody levels in cancer patients during COVID vaccines
This study measures COVID “neutralizing” antibodies over time in people with cancer who are on different kinds of cancer treatments. It aims to understand how vaccination and treatment type affect immune protection in cancer patients.
New Taipei CityAges 20 years+ - NCT05534009Recruiting
Study of healthcare workers’ COVID infection and vaccine history
This study gathers information about healthcare workers (adults) and tracks your past COVID-19 infection and vaccination history. It may help researchers understand how COVID affects healthcare workers and how vaccines relate to infection outcomes.
DüsseldorfAges 18 years+ - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT05858502Recruiting
Study immune response to COVID-19 and improve testing
This study looks at how the immune system in the body responds to different COVID-19 virus variants. It may help improve how COVID-19 is diagnosed by comparing people who are currently infected and those who are not.
ParisAges 18–65 - NCT06008860RecruitingPhase 4
Astepro nasal spray for early COVID-19
This trial tests whether Astepro nasal spray can help people with mild or no COVID-19 symptoms recover faster. If you have tested positive and are vaccinated, you may qualify.
Chicago, IllinoisAges 18 years+ - NCT06667063Recruiting
Immune response study for COVID-19 and flu
This study looks at how your immune system responds to COVID-19 or the flu. It may help researchers understand these infections better, whether you are currently sick or healthy.
Wuhan, HubeiAges 18 years+ - NCT06848309Recruiting
Immune response study for influenza or COVID-19
This study looks at how your immune system fights off flu or COVID-19. If you have a current or recent infection, or if you've been vaccinated in the past year, you may be able to join.
St Louis, MissouriAges 18–60 - NCT05787418Enrolling by invitationPhase 3
Nasal spray to prevent COVID-19 after a close exposure
This Phase 3 trial tests whether a medicated nasal spray can stop COVID-19 from starting after you’ve been exposed to someone who recently tested positive. You must start very soon after the person became symptomatic, and you’ll be checked for eligibility based on timing and your health history.
BeijingAges 12–85
Common questions
- Are there clinical trials studying COVID-19 vaccine?
- Yes. Clin2 currently lists 68 recruiting studies that include COVID-19 vaccine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a COVID-19 vaccine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is COVID-19 vaccine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether COVID-19 vaccine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.