Treatment
Fecal Microbiota Transplantation clinical trials
We’re tracking 105 recruiting studies that include Fecal Microbiota Transplantation, each written for real people, not researchers, below.
Recruiting studies
- NCT05786404RecruitingPhase 1
Fecal transplant study for people with active ulcerative colitis
This trial tests whether transplanting stool bacteria (called fecal microbiota transplantation, or FMT) can improve symptoms in people with active ulcerative colitis. You may be able to help test a new approach for restoring gut bacteria, while receiving standard ulcerative colitis care from your doctor.
Houston, TexasAges 18 years+ - NCT06478823Recruiting
Healthy stool donors for fecal transplant studies
This trial is looking for healthy stool donors to provide samples for fecal microbiota transplantation, a treatment that uses healthy bacteria from stool to help people with certain gut diseases. As a donor, you would give stool samples regularly to help others.
Paris, ParisAges 18–49 - NCT03787771Recruiting
Fecal transplant registry for donors and recipients
This is a registry that collects information from adults who either receive fecal microbiota transplant (FMT) or plan to receive it, and from people who have donated—or plan to donate—stool for FMT. It helps researchers understand who participates in these gut-microbiome treatments in real life.
Hong KongAges 18 years+ - NCT04970446RecruitingPhase 1/Phase 2
Fecal transplant to restore gut microbes in Crohn’s
This Phase 1/2 study tests whether a fecal microbiome transplant (FMT) can reduce active inflammation in people with Crohn’s disease. It’s designed for people who currently have signs of active bowel inflammation and can attend regular procedure visits.
Melbourne, VictoriaAges 18–70 - NCT05251389RecruitingPhase 1/Phase 2
Fecal microbiome transplant after anti-PD-1 melanoma not working
This trial tests whether a fecal microbiome transplant (FMT) can help your body respond better to anti-PD-1 immunotherapy in advanced skin melanoma. It is for people whose melanoma has progressed despite anti-PD-1 treatment.
AmsterdamAges 18 years+ - NCT05333471RecruitingPhase 1/Phase 2
Fecal transplant for chronic bowel inflammation in CGD
This study tests whether transplanting stool microbiome (fecal microbiota transplant) can improve chronic colitis in people with chronic granulomatous disease (CGD). It aims to reduce bowel inflammation and symptoms by changing gut bacteria.
Bethesda, MarylandAges 10–60 - NCT05669846RecruitingPhase 2
FMT plus pembrolizumab for advanced lung cancer after prior treatment
This Phase 2 trial studies whether adding fecal microbiome transplant (FMT) to pembrolizumab can help people with advanced, PD-L1–positive non-small cell lung cancer that has returned or progressed after anti–PD-1/PD-L1 therapy. You may be asked to give new tumor tissue and undergo gut procedures, because the study aims to change gut bacteria to boost the immune response.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05740319Recruiting
Test stool transplant to treat irritable bowel syndrome
This trial studies fecal microbiota transplantation, which is transferring stool bacteria from a healthy donor to help rebalance gut microbes. If you have irritable bowel syndrome (IBS) that hasn’t improved after several standard treatments, this study may see whether it reduces your symptoms and is safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06311006Recruiting
Safety registry for fecal transplant for C. diff
This registry tracks people who receive a fecal microbiota transplant (FMT) for a serious or repeat C. diff infection. It helps doctors better understand how safe and effective FMT is in real-world use.
ParisAges 18 years+ - NCT05321745Recruiting
Fecal transplant for children with Crohn’s disease
This trial tests whether transferring stool microbes (called fecal microbiota transplantation, or FMT) can improve Crohn’s disease in children who have not gotten better with usual treatments. If you qualify, the study will check symptoms and colon imaging/score changes over the study follow-up.
Wuhan, HubeiAges 2–16 - NCT06388863Recruiting
Fecal transplant for constipation in Parkinson's disease
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help relieve constipation in people with Parkinson's disease. FMT uses healthy donor stool to improve gut bacteria, which may ease constipation and possibly improve Parkinson's symptoms.
Shanghai, Shanghai MunicipalityAges 40–75 - NCT06403111RecruitingPhase 2
FMT with immunotherapy and chemotherapy for advanced lung cancer
This trial tests a combination of fecal microbiota transplantation (FMT), immunotherapy, and chemotherapy as a first treatment for advanced non-small cell lung cancer that does not have a driver gene mutation. The goal is to see if adding FMT can help the immune system fight the cancer better.
ChangzhouAges 18–80 - NCT06405113RecruitingPhase 2
Fecal transplant, chemo, and immunotherapy for advanced stomach cancer
This trial tests a combination of fecal microbiota transplant (FMT), chemotherapy (SOX), and an immunotherapy drug (Sintilimab) as a first treatment for advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors and improve outcomes.
ChangzhouAges 18–80 - NCT06451588RecruitingPhase 2
Fecal transplant for axial spondyloarthritis
This trial tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria from a donor into your gut) can help reduce inflammation and improve symptoms of axial spondyloarthritis. It may be an option if your disease is active despite current treatments.
TromsøAges 18–65 - NCT06623461RecruitingPhase 2
Fecal transplant with immunotherapy for advanced melanoma
This trial tests if giving a special capsule of donated bacteria (fecal transplant) alongside standard immunotherapy helps shrink tumors in people with advanced melanoma. It aims to see if adding the bacteria can make the immune therapy work better.
Abbotsford British Columbia, British ColumbiaAges 18 years+ - NCT07106580RecruitingPhase 1/Phase 2
Fecal transplant capsules for clearing drug-resistant bacteria from the gut
This trial tests whether taking capsules containing processed healthy donor stool (fecal microbiota transplant) can safely remove certain drug-resistant bacteria (like CRE, ESBL-E, and VRE) from your intestines. It may be an option for people who have these bacteria in their stool but are not currently being treated with antibiotics.
RijekaAges 18 years+ - NCT07153809Recruiting
Fecal transplant for severe acute pancreatitis recovery
This trial tests whether a fecal transplant (transferring healthy gut bacteria from a donor) can help people with severe acute pancreatitis. It is for adults who are about 2 weeks past the onset of the disease and have started to recover but still have fluid buildup in the pancreas.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07374094Recruiting
Understanding C. difficile infection and treatment effects
This study is tracking patients with a confirmed C. difficile infection to understand how the body responds and how treatments work. You may be asked to do follow-up visits for up to 5 years.
UmeåAges 18 years+ - NCT07381374Recruiting
Fecal transplant for children with autism
This trial tests whether fecal microbiota transplantation can help children with moderate-to-severe autism. It involves giving healthy donor bacteria to improve gut health and possibly autism symptoms.
Shenzhen, GuangdongAges 3–16 - NCT01793831Recruiting
Fecal transplant study for people with Crohn’s disease
This study tests whether a standardized stool-based treatment (fecal microbiota transplantation) can help people with Crohn’s disease. You may qualify if your Crohn’s diagnosis has been stable and you’re willing to receive the fecal transplant.
Huai'an, JiangsuAges Any age - NCT07464392Recruiting
Fecal transplant to prevent infections in severe pancreatitis
This trial tests whether a fecal microbiota transplant (FMT) can help prevent infections in people with moderately severe or severe acute pancreatitis. You may qualify if you are between 18 and 75, have had pancreatitis for 15 to 21 days, and already have a feeding tube in place.
Fuzhou, FujianAges 18–75 - NCT06692361Recruiting
Gut bacteria transplant for depression not helped by escitalopram
This trial tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with depression that does not respond well to the antidepressant escitalopram. You will first take escitalopram for 2 weeks, and if it doesn't help enough, you may receive either the real transplant or a placebo capsule.
Wuhu, AnhuiAges 18–65 - NCT06058520RecruitingEarly Phase 1
Capsule microbiome transplant for hidradenitis suppurativa
This trial tests whether taking capsules containing healthy gut bacteria (fecal microbiota transplant) can help treat hidradenitis suppurativa. You may qualify if you have HS and haven't taken antibiotics in the last 30 days.
Minneapolis, MinnesotaAges 18 years+
Common questions
- Are there clinical trials studying Fecal Microbiota Transplantation?
- Yes. Clin2 currently lists 105 recruiting studies that include Fecal Microbiota Transplantation, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Fecal Microbiota Transplantation trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Fecal Microbiota Transplantation an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Fecal Microbiota Transplantation or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.