Treatment
Hormone Therapy clinical trials
We’re tracking 132 recruiting studies that include Hormone Therapy, each written for real people, not researchers, below.
Recruiting studies
- NCT07848438Recruiting
Sex hormones and aging study
This study looks at how sex hormones affect the body as we age. Participants may help researchers understand changes in muscles, bones, or other functions, which could lead to better treatments for aging-related conditions.
Ann Arbor, MichiganAges 50–70 - NCT06957691RecruitingPhase 2
Fezolinetant for hot flashes in men on hormone therapy
This study tests a medication called fezolinetant to see if it reduces hot flashes in men undergoing hormone therapy for prostate cancer. If you experience frequent hot flashes, this treatment might help alleviate them.
Boston, MassachusettsAges 40 years+ - NCT06497894RecruitingPhase 4
Hormone therapy for sleep in late menopause
This trial tests whether hormone replacement therapy (HRT) can improve sleep for women in late menopause who have insomnia. If you are in late menopause and struggle with poor sleep, this study may offer a treatment option.
BernAges 45–69 - NCT07112053RecruitingPhase 2
Vaccine with hormone therapy or chemo for advanced breast cancer
This trial tests a vaccine (STEMVAC) given with your standard hormone therapy or chemotherapy. It is for people with advanced hormone receptor-positive, HER2-negative breast cancer who are already on certain treatments. The goal is to see if adding the vaccine can help control the cancer better.
Seattle, WashingtonAges 18 years+ - NCT07610720RecruitingPhase 2
Dalpiciclib With Anti-HER2 and Hormone Therapy for Advanced Breast Cancer
This trial tests a combination of three drugs—dalpiciclib (a new cell-cycle inhibitor), anti-HER2 therapy, and hormone therapy—for advanced breast cancer that is positive for both hormone receptors and HER2 protein. The goal is to help patients whose cancer has responded to initial treatment stay in remission longer.
Guangdong, GUANGZHOUAges 18–75 - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT06067269RecruitingPhase 2
Hormone therapy and precise radiation for intermediate-risk prostate cancer
This trial tests whether giving a short course of hormone therapy (apalutamide) along with targeted, high-dose radiation (SBRT) is safe and effective for men with a specific type of intermediate-risk prostate cancer. You may benefit if you fit the exact risk and test criteria.
Los Angeles, CaliforniaAges 18 years+ - NCT03972345Enrolling by invitation
Study on how sticking to growth hormone affects near adult height
This study looks at whether consistently taking growth hormone (Norditropin) helps children reach a height goal by “near final height.” It focuses on children who are short due to growth hormone deficiency or born small for gestational age.
UlmAges birth–15 years - NCT04457895Recruiting
Yoga and physical therapy program for hormone therapy breast cancer pain
This trial studies whether a combined physical therapy, yoga, and patient education program can reduce pain in people with non-metastatic breast cancer who are taking hormone therapy. It may help with pain and day-to-day comfort while you continue hormone treatment.
Libourne, AquitaineAges 18–99 - NCT07137871RecruitingPhase 1
Avasopasem for advanced HR+ breast cancer after CDK 4/6 inhibitor
This trial tests a drug called avasopasem for people with hormone receptor-positive, HER2-negative breast cancer that has spread and gotten worse despite treatment with a CDK 4/6 inhibitor (ribociclib or abemaciclib) and hormonal therapy. It aims to see if adding avasopasem can help control the cancer.
San Antonio, TexasAges 18 years+ - NCT06245681Recruiting
How Hormone Therapy Affects the Heart and Liver
This study looks at how cross-sex hormone treatment affects the heart and fat in the liver. It aims to help understand the safety of hormone therapy in transgender individuals.
Vienna, State of ViennaAges 18–99 - NCT07661927RecruitingPhase 2
Skipping hormone therapy for low-risk breast cancer
This trial tests whether women with very low-risk, early-stage breast cancer can safely skip hormone therapy after surgery. It is designed for women who are 60 or older and whose cancer shows no spread to lymph nodes and has favorable biology.
AngersAges 60 years+ - NCT07395804Recruiting
How darolutamide works for advanced prostate cancer in Germany
This study looks at how well a drug called darolutamide (a type of hormone therapy) works in everyday medical practice for men with advanced prostate cancer that has spread. It is for men who are already starting this treatment with their doctor and will help doctors understand how it works in real life.
LocationsAges 18 years+ - NCT04740697Recruiting
Complementary therapies to help people stay on tamoxifen
This study looks at whether adding alternative or complementary supports can improve how well people stick with tamoxifen treatment for early hormone-related breast cancer. If it helps adherence, it may help people benefit more reliably from their prescribed therapy.
ToulouseAges 1.5 years+ - NCT07751133RecruitingPhase 3
Hormone therapy dosing study for metastatic prostate cancer
This study tests different ways of giving hormone therapy to find the right dose for men with prostate cancer that has spread. It aims to help manage the disease while limiting side effects.
ManchesterAges 18 years+ - NCT05304962RecruitingPhase 1
Test drug RGT-419B for advanced ER+ HER2- breast cancer
This Phase 1 study tests a new drug (RGT-419B), given alone or with hormone (endocrine) therapy, in people with advanced ER-positive, HER2-negative breast cancer that has progressed after standard treatments. It looks mainly at safety and early signs of how well the treatment may work.
La Jolla, CaliforniaAges 18 years+ - NCT06931340RecruitingPhase 3
Adding chemo to hormone therapy for advanced prostate cancer
This trial is for men with metastatic prostate cancer that has already spread beyond the pelvis. It tests whether adding a chemotherapy drug (docetaxel) to the usual hormone therapy plus apalutamide can help control the cancer better than hormone therapy alone.
Tucson, ArizonaAges 18 years+ - NCT07407920RecruitingPhase 2
Optimizing treatment for early HER2+ and triple-negative breast cancer
This trial aims to see if patients who had a complete response to chemo before surgery can safely stop or reduce their targeted therapy afterward. It includes people with early-stage HER2-positive or triple-negative breast cancer who had no cancer cells left in the tissue removed at surgery (a pathological complete response).
Houston, TexasAges 18 years+ - NCT04666961RecruitingPhase 2
Hormone therapy before surgery for extensive DCIS
This Phase 2 study tests whether taking hormone medicine before surgery can change the surgical plan and outcomes for people with extensive ductal carcinoma in situ (DCIS). It is for estrogen-receptor positive DCIS and aims to see how this “neoadjuvant” approach affects treatment decisions.
AngersAges 40 years+ - NCT05586724RecruitingPhase 3
Progesterone vs another hormone added to estrogen for menopause symptoms
This Phase 3 study compares two types of progesterone—micronized progesterone versus norethisterone acetate—both used with estrogen to treat menopause symptoms that affect daily life. It aims to see which combination works better and is tolerated over time for women with an intact uterus.
StockholmAges 45–60 - NCT05720260RecruitingPhase 2
Test immunotherapy plus hormone therapy and an AKT blocker
This trial tests whether combining immunotherapy, hormone therapy, and an AKT-blocking drug can control ER-positive advanced breast cancer in women whose cancer is resistant to hormone treatment. It may help shrink tumors and slow disease by targeting several pathways at once.
TaipeiAges 20 years+ - NCT06792201Recruiting
Sarcopenia study in women at different life stages
This trial looks at muscle loss (sarcopenia) in women who are pre-menopause or post-menopause, and whether hormone replacement therapy affects it. It aims to understand how muscle health changes over a woman's life.
BolognaAges 18–65 - NCT07400419Recruiting
Resistance exercise for transgender individuals starting estrogen therapy
This study looks at whether doing resistance training (like lifting weights) can help people who are starting estrogen-based hormone therapy as part of their gender transition. It focuses on how exercise might affect body strength and health during this time.
Boston, MassachusettsAges 18 years+ - NCT07310485Enrolling by invitation
Soy supplements for premenstrual syndrome in women approaching menopause
This study tests whether taking phytoestrogens (plant-based compounds that act like estrogen) can reduce premenstrual syndrome symptoms and affect gene expression in healthy women in their 40s and 50s. It may help women who are still having regular periods but are approaching menopause.
Amman, Amman GovernorateAges 40–55
Common questions
- Are there clinical trials studying Hormone Therapy?
- Yes. Clin2 currently lists 132 recruiting studies that include Hormone Therapy, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Hormone Therapy trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Hormone Therapy an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Hormone Therapy or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.