Treatment
S-1 clinical trials
We’re tracking 801 recruiting studies that include S-1, each written for real people, not researchers, below.
Recruiting studies
- NCT06574360RecruitingPhase 2
Study of a dual-target drug for hard-to-treat schizophrenia
This trial tests an experimental combination treatment that targets two different brain receptors (sigma-1 and NMDA) to see if it can improve symptoms in people with schizophrenia that hasn't responded well to standard antipsychotics.
TaichungAges 18–65 - NCT06582875RecruitingPhase 2
GLP-1 drug for polycystic kidney disease and weight
This study tests a GLP-1 receptor agonist (a type of medicine that helps with weight and metabolism) in people with polycystic kidney disease who are overweight. It aims to see if this drug can help slow kidney disease progression.
Aurora, ColoradoAges 18–65 - NCT06587802RecruitingPhase 2
PD-1 antibody and radiation for advanced adrenal cancer
This trial tests a combination of an immunotherapy drug (PD-1 antibody) and radiation therapy for people with adrenal cortical carcinoma that has come back or spread and can't be removed with surgery. The goal is to see if this combination can help shrink or control the cancer when other treatments have stopped working.
Guangzhou, GuangdongAges 18 years+ - NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Chandler, ArizonaAges 18 years+ - NCT06607120Recruiting
Trial for advanced liver cancer with TACE and immunotherapy
This trial is for people with advanced liver cancer (HCC) that has spread outside the liver or into major blood vessels. It tests combining a procedure called TACE with immunotherapy (PD-1/PD-L1 inhibitors) and targeted drugs to see how well they work together.
Nanjing, JiangsuAges 18 years+ - NCT06613165Recruiting
Short vs long treatment for stage II-III rectal cancer with dMMR
This trial tests how long you need a PD-1 immunotherapy before surgery for a specific type of rectal cancer (dMMR/MSI-H). It looks at whether a shorter or longer course works best. This could mean fewer side effects and a quicker path to surgery.
Xi'an, ShaanxiAges 18–80 - NCT06634849RecruitingPhase 1/Phase 2
Study of a new drug (PTT-4256) for advanced solid tumors
This trial tests a new drug called PTT-4256 for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find the best dose and see if it helps shrink or control the cancer.
Blacktown, New South WalesAges 18 years+ - NCT06634979Recruiting
Selective lymph node removal for small lung cancers
This trial compares removing fewer lymph nodes during surgery for early-stage non-small cell lung cancer. It is for people with a small tumor (2 cm or less) that has both solid and ground-glass parts.
ShanghaiAges 18–80 - NCT06666049Recruiting
Ultrasound test on the stomach before surgery in patients taking GLP-1 drugs
This trial uses a stomach ultrasound (called gastric POCUS) to check if your stomach is empty before surgery. It is for patients taking GLP-1 medications (like Ozempic, Wegovy, or similar) to help make sure it is safe to proceed with anesthesia.
Madrid, MadridAges 18–90 - NCT06670248Recruiting
Study of blood vessel health during burn surgery
This trial looks at how a protective layer inside your blood vessels (called the glycocalyx) responds during surgery to remove burned skin. The goal is to improve care for people with major burns.
Barcelona, SpainAges 18 years+ - NCT06675214RecruitingPhase 3
Immunotherapy with modified radiation for advanced NPC
This trial tests a new way to give radiation therapy after immunotherapy and chemotherapy for people with advanced nasopharyngeal cancer (NPC) that has partially shrunk. It aims to see if a different radiation schedule works better and has fewer side effects.
Zhuhai, GuangdongAges 18–65 - NCT06681688RecruitingPhase 1/Phase 2
Comparing two approaches to prevent cataract surgery complications
This study compares two ways to prevent complications after cataract surgery. One group gets a special combination of eye drops and a steroid injection before surgery, and the other group gets standard care. The goal is to see which approach leads to fewer problems after surgery.
Venice, FloridaAges 18 years+ - NCT06691321Recruiting
Caspofungin for Pneumocystis Pneumonia in HIV patients
This trial tests caspofungin, a medicine, for treating Pneumocystis pneumonia (PCP) in people living with HIV. It aims to see if it works better than standard treatments.
Mexico City, TlalpanAges 18–60 - NCT06698003RecruitingPhase 2
Mogamulizumab to Prevent Leukemia in HTLV-1 Carriers
This trial tests whether a drug called mogamulizumab can prevent adult T-cell leukemia/lymphoma in people who carry the HTLV-1 virus and have a high viral load. It is for patients who have not yet developed the blood cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT07687875RecruitingPhase 1
Virus therapy plus immunotherapy before surgery for rectal cancer
This trial tests a combination of a cancer-killing virus (oncolytic virotherapy) and an immunotherapy drug (pembrolizumab) given before surgery for a certain type of rectal cancer. It aims to see if this approach helps shrink the tumor and improve outcomes for patients whose tumors have a normal DNA repair system (pMMR).
Copenhagen, Captial RegionAges 18 years+ - NCT07307235RecruitingPhase 4
Comparing a new diabetes combination to standard care for type 2 diabetes
This trial tests if a once-daily injectable combination (iGlarLixi) helps control blood sugar better than usual care for people with type 2 diabetes who are already taking diabetes pills. It aims to find a more effective treatment option.
Hefei, AnhuiAges 18 years+ - NCT07686575Recruiting
Ivonescimab with chemo for advanced mouth or throat cancer
This trial tests a new drug, ivonescimab, combined with chemotherapy for people with advanced mouth or throat cancer that can be removed with surgery. The goal is to see if the combination helps shrink tumors before surgery.
Guangzhou, GuangdongAges 18–80 - NCT07625345RecruitingPhase 1
Brain Imaging Study of PDE4B Using a Radioactive Tracer
This research study uses a special radioactive tracer and imaging machines (PET and MRI scans) to take pictures of a specific protein in your brain called PDE4B. This is an early-stage study to see if this imaging method works safely and can help us understand brain chemistry in the future.
Bethesda, MarylandAges 18–101 - NCT07403136RecruitingPhase 2
Testing Becotatug Vedotin ± Immunotherapy for advanced esophageal cancer
This trial tests a new targeted drug (Becotatug Vedotin) given either alone or with an immunotherapy drug for people with advanced esophageal squamous cell cancer that has EGFR protein on their tumor cells. The goal is to see if this combination can help when standard treatments have stopped working.
ShanghaiAges 18 years+ - NCT07687589Enrolling by invitation
Testing a gut hormone for nausea in healthy adults
This study tests whether a natural gut hormone called GIP can reduce nausea by increasing blood flow to the gut. Researchers want to see how this works in healthy people.
HellerupAges 18–60 - NCT06780085RecruitingPhase 2
Study of new drugs for advanced lung cancer
This trial tests new treatments for people with stage IV nonsquamous non-small cell lung cancer that has gotten worse after prior immunotherapy and chemotherapy. It aims to find better options for those whose cancer has specific genetic features.
Lexington, KentuckyAges 18 years+ - NCT06714253RecruitingPhase 1/Phase 2
Circular RNA treatment for dry mouth after radiation
This trial tests a new type of treatment called circular RNA to see if it can help people with long-term dry mouth after radiation for head and neck cancer. It's for patients whose dry mouth hasn't gone away with other treatments.
Iowa City, IowaAges 18 years+ - NCT06718257Recruiting
Chemo with immunotherapy and targeted drugs for bile duct cancer
This trial tests whether adding immunotherapy and targeted therapy to standard chemotherapy can help treat intrahepatic cholangiocarcinoma (a type of bile duct cancer). It is for patients who are starting treatment with one of two specific chemo regimens, possibly combined with the new drugs.
Hangzhou, ZhejiangAges 18 years+ - NCT06725693Recruiting
PET scan using GLP-1 receptor tracer for cancers
This trial uses a special PET scan (a 3D imaging test) to look for cancer cells that have GLP-1 receptors, a protein on some tumors. It aims to see if this scan can help find or monitor cancer.
Tianjin, Tianjin MunicipalityAges 18–80
Common questions
- Are there clinical trials studying S-1?
- Yes. Clin2 currently lists 801 recruiting studies that include S-1, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a S-1 trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is S-1 an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether S-1 or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.