Treatment
Treatment as Usual clinical trials
We’re tracking 315 recruiting studies that include Treatment as Usual, each written for real people, not researchers, below.
Recruiting studies
- NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT05706376Recruiting
Family support program for Palestinian teens and parents
This study tests an evidence-based family support program that involves parents and adolescents together. It may help families improve support and wellbeing by giving structured guidance and group-based sessions.
Notre Dame, IndianaAges 12–75 - NCT05691647Recruiting
Testing timing-based treatment for a new depressive episode
This trial studies whether “chronotherapy” (carefully timing daily activities/therapies) can help people with a new moderate to severe depression episode. You may be eligible if your depression is recent and fairly severe, and if your daily schedule can support the timing plan.
TrondheimAges 18–100 - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+ - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70 - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+ - NCT05493254Recruiting
Telehealth help to quit smoking in primary care visits
This study tests a phone/video-based program to help people quit smoking through primary care. It may help you get support and track your progress remotely.
Charleston, South CarolinaAges 18 years+ - NCT05415007Recruiting
Support program for parents and teens after a new cancer diagnosis
This study tests a brief program meant to reduce anxiety and build resilience in families when a child was newly diagnosed with cancer. It involves both the parent and the child (ages 8–17) and requires consent/assent and English ability.
San Francisco, CaliforniaAges 8–18 - NCT05208190RecruitingPhase 4
Clozapine to prevent violence in schizophrenia
This trial tests whether clozapine can reduce repeat violent behavior in people with schizophrenia or schizoaffective disorder. Participants are randomly assigned to clozapine or usual care to see which approach works better for preventing violence.
Los Angeles, CaliforniaAges 18–65 - NCT05142683Recruiting
Test an integrated care plan for teens with depression
This study tests whether a structured, coordinated care pathway helps teens (and their caregivers) manage depression better than usual care. It aims to see if targeted treatment and follow-up improve depression symptoms over time.
Toronto, OntarioAges 13–18 - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT04937309Recruiting
Vagus nerve stimulation for nausea from chemo
This trial tests a non-invasive device that stimulates a nerve in your ear to help prevent nausea caused by chemotherapy. It is for people with breast cancer who are about to start a specific type of chemo (anthracycline and cyclophosphamide).
BloisAges 18 years+ - NCT04797455Recruiting
Parent program for teens in inpatient mental health care
This study tests an intervention (a structured parent-focused program) for parents of teens who are currently hospitalized for suicidal thoughts or a suicide attempt. It may help families learn ways to support their teen during and after hospitalization.
Stanford, CaliforniaAges 12–85 - NCT03769259Enrolling by invitation
Therapy for recent suicidal thoughts or attempts
This study tests a brief counseling approach based on cognitive behavioral therapy to help people who are dealing with suicidal thoughts or a recent suicide attempt. It’s offered in outpatient care and aims to see whether this shorter therapy works for improving safety and coping.
Jacksonville, North CarolinaAges 18 years+ - NCT07166120Recruiting
A tailored approach to help cancer patients quit smoking
This trial tests a personalized treatment plan to help people with cancer stop smoking. Researchers will see if matching you with the right medication (like the nicotine patch, lozenge, or varenicline) can improve your chances of quitting and living longer.
St Louis, MissouriAges 18–89 - NCT06433271Recruiting
Therapy study for adjustment disorder after trauma
This study compares a new type of talk therapy (Transdiagnostic Behavior Therapy) to standard care for veterans and active military members who are struggling with adjustment disorder after a traumatic event. The goal is to see which approach helps people feel better and adjust to life after trauma.
Charleston, South CarolinaAges 18 years+ - NCT07453758Enrolling by invitation
Suicide prevention program for Tajik women
This trial tests a program led by nurses and peers to help Tajik women who are at risk for suicide. If you have had recent suicidal thoughts or a recent suicide attempt, this program may offer support.
DushanbeAges 18–59 - NCT06939192Recruiting
Digital support for families of preterm babies
This study tests an e-health program to help families of babies born between 28 and 34 weeks. The program provides online tools and guidance, aiming to improve health and development.
Tübingen, Baden-WurttembergAges 6 months–8 months - NCT06702670RecruitingPhase 2/Phase 3
Anticholinergics for cervical edema in labor
This trial tests if a medication (diphenhydramine) can help reduce swelling in the cervix during labor for first-time mothers. It may make labor progress more smoothly.
Houston, TexasAges 18 years+ - NCT05673148RecruitingPhase 2
Adding targeted tumor treatment to standard therapy for limited metastatic colorectal cancer
This trial tests whether adding a precise, targeted treatment to destroy remaining cancer spots (called total ablative therapy) after initial chemotherapy can improve outcomes for people with limited metastatic colorectal cancer. It aims to see if this extra treatment is safe and effective.
Kingman, ArizonaAges 18 years+ - NCT04301076RecruitingPhase 1
Testing lenalidomide with EPOCH for adult T-cell leukemia-lymphoma
This trial tests whether adding lenalidomide to a standard chemotherapy regimen (EPOCH) helps people with adult T-cell leukemia-lymphoma (ATLL). It aims to improve how well the treatment works.
Atlanta, GeorgiaAges 18 years+ - NCT07161661Recruiting
Osteopathic treatment for chronic low back pain in veterans
This trial tests whether adding osteopathic manipulative treatment (OMT) to standard VA care helps reduce chronic low back pain. OMT involves a healthcare provider using their hands to move and stretch muscles and joints.
Hines, IllinoisAges 18 years+ - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+
Common questions
- Are there clinical trials studying Treatment as Usual?
- Yes. Clin2 currently lists 315 recruiting studies that include Treatment as Usual, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Treatment as Usual trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Treatment as Usual an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Treatment as Usual or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.