Treatment clinical trials

A study of VSJ-110 for dry eye disease

This trial tests a new eye drop called VSJ-110 to see if it is safe and effective for treating dry eye, compared to a placebo (inactive drops). It lasts 8 weeks and may help if you have dry eye symptoms.

Focused ultrasound for glioblastoma during standard chemo

This trial tests whether focused ultrasound can safely open the blood-brain barrier to help your chemotherapy work better. It is for people with glioblastoma who have already completed standard surgery and chemo-radiation and are now on maintenance chemo.

Long-term effects of HIFU for rectal endometriosis

This study checks how well High-Intensity Focused Ultrasound (HIFU) treatment works over time for people with rectal endometriosis. It's for those who already had HIFU in one of the earlier studies and want to help researchers understand long-term results.

Sacituzumab Tirumotecan and Tagitanlimab for aggressive prostate cancer

This trial tests a combination of two drugs for men with aggressive or neuroendocrine prostate cancer that has worsened after previous hormone therapy. The goal is to see if the combination can shrink tumors or slow the disease.

Better cervical cancer screening for women with HIV in Cameroon

This study tests a mobile team approach to screen for cervical cancer using HPV testing in women living with HIV. It aims to make screening easier to access and more effective.

Testing lower doses of linvoseltamab for multiple myeloma

This trial tests if a lower dose of linvoseltamab can still work well for people with multiple myeloma that has come back or not responded to treatment. It aims to reduce side effects while keeping the cancer under control.

Brain stimulation device for Parkinson's motor symptoms

This trial tests a wearable brain stimulation device (tES) that delivers gentle electrical currents to your head to help improve Parkinson's motor symptoms like tremor, stiffness, or slowness. The treatment is done at home with remote video monitoring, and may offer a non-medication option to help with movement.

Short radiation plus chemotheapy and immunotherapy before surgery for junction cancer

This trial tests a combination of shortened radiation therapy, immunotherapy, and chemotherapy given before surgery for cancer at the junction of the esophagus and stomach. The goal is to see if this approach is safe and improves outcomes.

Study of SKB264 plus Inetetamab for advanced HER2+ breast cancer after T-DXd

This trial is testing a combination of two targeted therapies, SKB264 and Inetetamab, for people with advanced HER2-positive breast cancer that has kept growing after treatment with T-DXd and other HER2-targeted therapies. The goal is to see if this new combination can shrink tumors or slow the cancer's growth.

New drug combo vs standard for EGFR-mutated lung cancer

This trial tests whether adding a new targeted drug (SHR-A2009) to the standard pill aumolertinib works better than aumolertinib alone for people with advanced lung cancer that has an EGFR mutation. It's for those who haven't had treatment yet.

Clot-busting drug through artery for medium-vessel stroke

This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.

Testing natural killer cells for leftover lung nodules

This trial is testing a new treatment using your own immune cells (called NK cells) to fight leftover high-risk lung nodules that cannot be surgically removed. It is for people who have already had some cancerous nodules removed and are looking for another option.

Sound treatment for chronic tinnitus

This study tests whether a special sound-based treatment can help people with chronic tinnitus (ringing in the ears). If your tinnitus has lasted more than six months and you don't have other ear or brain problems, you may be able to join.

New PTSD therapy for children ages 6-14

This study tests a new therapy for children with PTSD. It aims to help children aged 6-14 reduce trauma symptoms by teaching them skills to manage distressing memories and feelings.

Device to treat gum shrinkage and black triangles between teeth

This trial tests a medical device (RDM36) to see if it safely and effectively treats gum shrinkage and black triangles between the front teeth, which can affect your smile.

Testing 626 for lupus: a phase 1/2 study

This trial tests a new drug called 626 for people with systemic lupus erythematosus (SLE). It aims to see if the drug is safe and effective at reducing disease activity.

Ketorolac Use and Fresh Embryo Transfer Outcomes

Study of a long-acting cariprazine shot for mood and schizophrenia

This trial tests a monthly injection of cariprazine (a medication for mental health conditions) in people who could benefit from it. It aims to see if the shot is safe, tolerable, and effective compared to taking pills every day.

Testing HSK21542 for pain after hip replacement surgery

This trial tests a new pain medicine called HSK21542 for people who have hip replacement surgery under general anesthesia. It aims to see if the drug can safely reduce moderate to severe pain after surgery.

Radiofrequency skin tightening study for loose skin and wrinkles

This study tests a radiofrequency device called Thermage® FLX to see how well it tightens skin and reduces wrinkles on the neck, face, belly, or upper arms. It may be a good option if you have mild to moderate skin looseness or lines and haven't had recent cosmetic procedures.

Acupuncture for shoulder pain after a car accident

This study tests if a special acupuncture technique can help relieve shoulder pain and improve movement after a car accident. It is for adults hospitalized with recent shoulder pain.

Skin cell transplant for vitiligo treatment

This trial tests a surgery that uses your own skin cells to treat stable vitiligo patches. It may help when creams or light therapy haven't worked.

Study of pucotenlimab with lenvatinib and chemo for relapsed hepatoblastoma in children

This trial tests a combination of an immunotherapy (pucotenlimab), a targeted therapy (lenvatinib), and chemotherapy for children with advanced or relapsed hepatoblastoma that hasn't responded to prior treatment. The goal is to see if this combination can help shrink or control the tumor.

Treating newly diagnosed central malignant germ cell tumors with teniposide and cisplatin

This trial tests a combination of two chemotherapy drugs—teniposide and cisplatin—for people who have just been diagnosed with a malignant germ cell tumor in the brain. The goal is to see if this treatment is safe and effective.