Ramipril for walking pain from blocked leg arteries
Treatments studied
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation clinical trials.
This study tests whether ramipril (a blood-pressure medicine) can improve leg muscle problems linked to poor blood flow in people with chronic claudication—pain that limits walking. It’s mainly looking at changes related to oxidative stress and muscle scarring (fibrosis).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a history of long-lasting claudication (walking pain from poor leg blood flow).
- Your leg pain limits walking, and a doctor confirms it during a treadmill/walking test.
- You have blocked leg arteries, shown by a circulation test like an ankle-brachial index and/or imaging.
- Your blood pressure, cholesterol, and diabetes medicines (if you have diabetes) and risk-factor control have been stable for at least 6 weeks.
- You are not already taking ACE-inhibitor blood-pressure medicines, including ramipril or similar drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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