Defibrillator device vs medicines for a rare heart spasm after arrest
Treatments studied
Part of Heart & circulation, Pain clinical trials.
This trial compares an implantable defibrillator device plus best care versus best medicines alone in people who survived a cardiac arrest caused by a specific abnormal heart rhythm. It focuses on variant angina, where a heart-spasm problem can trigger dangerous rhythm events, to see which approach prevents future events.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older.
- You survived (were successfully resuscitated from) a cardiac arrest caused by ventricular fibrillation or sustained fast ventricular tachycardia.
- Your doctors diagnosed variant angina from evidence of a coronary (heart blood vessel) spasm on tests.
- You do NOT have major (more than 50%) blockage in the heart arteries on angiogram testing.
- You have not previously had a pacemaker or an implantable defibrillator, and you have not had prior catheter ablation for a dangerous rhythm.
- You do not have certain heart muscle/electrical conditions, severe heart failure symptoms (NYHA class III/IV), or a limited life expectancy (less than 2 years).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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