Medication and defibrillators for non-ischemic cardiomyopathy
Part of Heart & circulation clinical trials.
This study compares modern heart failure medications and implantable cardioverter-defibrillators (ICDs) to reduce the risk of sudden cardiac death in people with a specific type of heart muscle disease (non-ischemic cardiomyopathy) that is not caused by blocked arteries. It may help guide treatment decisions for those with a weakened heart and certain scarring on heart MRI.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a heart muscle disease not caused by blocked arteries (non-ischemic cardiomyopathy).
- Your heart's pumping strength is reduced to 35% or less (measured by an ejection fraction test).
- You have a specific type of scarring in the heart muscle visible on an MRI (called late gadolinium enhancement).
- You have mild to moderate heart failure symptoms (NYHA class I to III) – not severe symptoms at rest.
- You have been on optimal heart failure medications for at least 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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