Clinical trials
REM Sleep Behavior Disorder clinical trials
Below are recruiting rem sleep behavior disorder clinical trials, each written for real people, not researchers. We’re tracking 33 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06996652RecruitingPhase 2
Study of adalimumab to delay Parkinson's symptoms in sleep disorder
This trial tests whether adalimumab, an immune system drug, helps people with REM sleep behavior disorder (a condition that may warn of Parkinson's disease) stay healthy longer. Participants will receive injections of the drug or a placebo to see if it prevents Parkinson's-related brain problems.
Los Angeles, CaliforniaAges 50–80 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT05262543Recruiting
Study predicts risk of RBD turning into Parkinson’s
This study looks at people diagnosed with idiopathic REM sleep behavior disorder (a sleep problem where you act out dreams) and tries to predict who may later develop another condition related to Parkinson’s. If you qualify and consent, you may be followed to understand risk factors and improve early identification.
Oggebbio, VerbaniaAges 18 years+ - NCT05321355Recruiting
Sleep disorder patient registry for narcolepsy and other conditions
This is a research registry that collects information from people with narcolepsy and other neurological sleep disorders. It may help doctors better understand sleep problems and improve future care.
Mainz, Rhineland-PalatinateAges 18–120 - NCT05471960Recruiting
Brain training study in people with REM sleep behavior disorder
This study looks at how the brain changes (“neuroplasticity”) in people diagnosed with isolated REM sleep behavior disorder (iRBD) using brain stimulation and other testing. Results may help researchers understand brain differences in iRBD and guide future treatments.
Minneapolis, MinnesotaAges 21–75 - NCT05721911Recruiting
Study using brain-cell tests to better understand Parkinson’s risk
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
Milan, ItalyAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06270290Recruiting
Concussions and contact sports in RBD patients versus controls
This trial looks at whether people with REM sleep behavior disorder (RBD) have more concussions or contact sports history than people without RBD, to see if head injuries might be linked to the condition.
London, LondonAges 50 years+ - NCT06329453Recruiting
Gut immunity and brain health study
This study looks at how your gut's immune system relates to brain and nerve diseases. Researchers will collect samples during a colonoscopy to better understand connections between gut health and neurologic conditions like multiple sclerosis or Parkinson's disease.
North Haven, ConnecticutAges 18–99 - NCT06441864Recruiting
Behavioral treatment for nightmares in REM sleep behavior disorder
This study tests a behavioral therapy (non-drug treatment) for nightmares in people with REM sleep behavior disorder (RBD). It's designed for you and a family member who lives with you.
Salt Lake City, UtahAges 18 years+ - NCT06582121Recruiting
Sleep disorders in early and advanced Parkinson's disease
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
Clermont-FerrandAges 18 years+ - NCT06629207Recruiting
AI predicts Parkinson's risk in sleep behavior disorder
This study uses artificial intelligence to analyze brain scans and predict whether people with REM sleep behavior disorder are at risk of developing Parkinson's disease. It aims to find early signs before symptoms appear.
BernAges 18 years+ - NCT06797284Recruiting
Light, electrical, and magnetic therapy for sleep issues
This study tests if light, electrical, or magnetic treatments can help people with insomnia, narcolepsy, or REM sleep behavior disorder improve their sleep-wake problems. It compares these gentle brain stimulation methods to understand which works best.
Suzhou, JiangsuAges 8–75 - NCT06975709Recruiting
Link between jaw pain and sleep problems
This study looks at how jaw joint disorders (TMJ) are related to sleep issues like insomnia, sleep apnea, or restless legs. If you have a sleep disorder, you may help researchers understand the connection.
Milan, ItalyAges 18 years+ - NCT07217054Recruiting
Parkinson's and RBD diagnosis via colon biopsy
This trial uses a small piece of colon tissue, taken during a routine colonoscopy, to look for a protein linked to Parkinson's disease and REM sleep behavior disorder (RBD). It aims to improve diagnosis for these conditions.
Branford, ConnecticutAges 40–99 - NCT07355842Recruiting
Can slow brain waves slow Parkinson's?
This study tests whether playing soft sounds during deep sleep can slow down brain changes in people with REM sleep behavior disorder (a condition linked to Parkinson's disease). It is for people who have this sleep disorder or were recently diagnosed with Parkinson's, and are not yet on Parkinson's medications.
Zurich, Canton of ZurichAges Any age - NCT07361315Recruiting
Online course for people with parasomnias
This study tests an online course for adults who have parasomnias (disruptive sleep behaviors like sleepwalking or night terrors). The goal is to see if the course helps manage symptoms. You may be a good fit if your doctor referred you and you have had parasomnia for at least 6 months.
Winnipeg, ManitobaAges 18 years+ - NCT07365566Recruiting
Pain and sleep behavior disorder study
This study looks at pain in people with a sleep condition called idiopathic REM sleep behavior disorder (iRBD), where people act out their dreams. It also includes a group of people with narcolepsy who have similar sleep issues. The goal is to understand how pain relates to these conditions.
ToulouseAges 18 years+ - NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Boston, MassachusettsAges 18 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07498452Recruiting
Sleep behavior study for patients and their partners
This study looks at the needs of people with isolated REM sleep behavior disorder (iRBD) and the people close to them. It aims to understand how this condition affects daily life and relationships.
Bologna, Emilia-RomagnaAges Any age - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100
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REM Sleep Behavior Disorder trials by city
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REM Sleep Behavior Disorder trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for rem sleep behavior disorder?
- Yes. Clin2 currently lists 33 recruiting rem sleep behavior disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rem sleep behavior disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rem sleep behavior disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.