Brain stimulation trial for depression that hasn’t improved
Part of Mental health clinical trials.
This trial tests a targeted deep brain stimulation procedure to reduce symptoms in people with long-lasting, treatment-resistant depression. It may help by improving mood symptoms using stimulation guided by detailed brain imaging.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 21 to 70, and you must not be pregnant
- Have major depression diagnosed in adulthood that has lasted a long time (or keeps coming back)
- Have tried at least four different depression treatments without enough improvement
- Have significant symptoms right now and measurable severity scores before surgery
- Have a normal recent brain MRI (within 3 months) and be able to get MRIs
- Be healthy enough for brain surgery and avoid certain implants or bleeding risks
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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