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NCT04500899Possibly a fitRecruiting

Phenylephrine test to better grade mitral valve leak severity

Mitral Regurgitation

Part of Heart & circulation clinical trials.

This trial tests whether a medication called phenylephrine helps doctors measure how severe mitral regurgitation (mitral valve leak) is. If you’re already scheduled for a special ultrasound from the esophagus, this study may help improve how your valve leak is assessed.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
35 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are age 18 or older.
  • You have mitral regurgitation (mitral valve leak) seen on your first ultrasound test.
  • You are scheduled to get a TEE (an ultrasound probe placed in the esophagus) to further evaluate the leak.
  • You must be considered safe enough to have a TEE by your care team.
  • You should not have major breathing or circulation instability around the test (your team should judge this).
  • Your blood pressure and heart rhythm should be stable enough for the medication test, and you should not have certain serious heart and brain risks.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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